Murphy Lab
@_Murphy_Lab
Structural and mechanistic study of proteins, especially redox- and metalloproteins
Our elemental mapping work, combining cryo-EM and EELS to REEL analysis, is now also published on Nature Methods: nature.com/articles/s4159… For a highlight “reel”, see here 👇
Happy to announce that our efforts to establish elemental mapping for cryo-EM ❄️ by EELS 🌈 are now shared on bioRxiv: biorxiv.org/content/10.110… Congratulations to @zoliviapg and co-authors! But wait - Can we map elements in 3D? 🧵👇 1/6
Happy to share that our work on the FDX2-bound core ISC complex is now published in @NatureComms 🎉 nature.com/articles/s4146… By the way, we are now also on @bluesky! 🦋 bsky.app/profile/bjmurp…
🎉 Our latest preprint is now online 👉 biorxiv.org/content/10.110… Congrats to @RalfSteinhilper who determined #cryoEM structures of the ferredoxin 2-bound core iron-sulfur cluster assembly complex under reducing and turnover conditions at 2 Å resolution. More below! 👇 🧵 1/8
Happy to see our study on the structure of 46-kDa Streptococcus pneumoniae NOX out in @NatureSMB! Congratulations to the authors @PABLOSANSEGUND3 and @vicsnorr 🥳 Check it out here (open-access) 👉 t.ly/T0oej
Excited to share our preprint: “Structural and mechanistic insights into Streptococcus pneumoniae NADPH oxidase” in which we obtained a structure of a 46-kDa membrane protein to 2.2 Å resolution without fiducials. tinyurl.com/zycuw3p6