Joseph Watson
@_JosephWatson
Co-Founder @ Xaira Therapeutics Former Baker Lab PostDoc at @UWproteindesign. Interested in generative modelling for molecular design. Views my own.
I’m excited to share our significantly-updated preprint on de novo antibody design, where we now demonstrate the structurally accurate design of scFvs (in addition to VHHs) with RFdiffusion! biorxiv.org/content/10.110…
@CalSleeper really love travelling on your sleeper trains! Why not allow for booking 1 berth in cabins whilst keeping the option to book the full cabin? Would increase the number of people who could travel by train instead of flying! Feels quite a waste of berths atm 🤷♂️
All the big things happening to all the best Davids! Congratulations David 😍
⚛️ I got a new job ⚛️ After 5 wonderful years at @UWproteindesign and @UWMolES, I’m headed to Palo Alto for a postdoc at @StanfordUChem under Todd Martinez. SUPER excited to dive into deep learning for quantum chemistry and explore the Bay Area!!
Congratulations to all - incredibly deserved! It was a total and constant honour working with David. His passion for protein design and its applications, as well as his uncanny attention to detail continue to inspire me. And nothing we do today would be possible without AlphaFold
BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
Very exciting to see this work out! It still feels quite amazing that you can take three functional bits of protein and bring them all together with novel scaffolds, all while retaining their native function. Congratulations to @karla_mcastro for leading this super cool project!
protein design is getting weird ... and increasingly functional ! These are very weird designs ! biorxiv.org/content/10.110… fun collaboration with @karla_mcastro @_JosephWatson @jueseph @UWproteindesign
A great day for science! Congratulations to the teams at @GoogleDeepMind @IsomorphicLabs!!
Announcing AlphaFold 3: our state-of-the-art AI model for predicting the structure and interactions of all life’s molecules. 🧬 Here’s how we built it with @IsomorphicLabs and what it means for biology. 🧵 dpmd.ai/3URDiNo
I am pleased to share that I have accepted a position @Stanford to start as an assistant professor in the department of statistics, with an affiliation in @StanfordData, this fall!
Congrats to my amazing PhD supervisor Manu!!
Announcing AlphaFold 3: our state-of-the-art AI model for predicting the structure and interactions of all life’s molecules. 🧬 Here’s how we built it with @IsomorphicLabs and what it means for biology. 🧵 dpmd.ai/3URDiNo
Our review on diffusion models for protein structures and docking is out @HannesStaerk @GabriCorso Bowen Jing @BarzilayRegina Tommi Jaakkola. This summarize the advancements up to 2023. There have been lots of exciting new works since! wires.onlinelibrary.wiley.com/doi/10.1002/wc…