Yilong Zou Lab

New online! A marker for sterol-dependent metastatic tropism bit.ly/4kIhqOc

This week we publish in @NatureBiotech "High-precision cytosine base editors by evolving nucleic-acid-recognition hotspots in deaminase". In this work, we show that both nucleotide and context specificity of deaminases can be reprogrammed by hotspot-focused directed evolution 1/n

mScarlet3-H (aka mYongHong) is on the cover of Nature Methods! All plasmids are available for free from WeKwikGene wekwikgene.wllsb.edu.cn/publications/7…

Thrilled to share our new Nature Chemical Biology study online today! We’ve uncovered a “lipid clock” ⏰within yeast cells, revealing temporal oscillations in phospholipid abundance during the metabolic/cell division cycle. #Lipids #BiologicalRhythm #Cell nature.com/articles/s4158…

In the latest issue! ACSL4 and polyunsaturated lipids support metastatic extravasation and colonization dlvr.it/THp8cc

MethylTree developed by Wang and colleagues from @Westlake_Uni offers a non-invasive lineage tracing tool by using scBS-seq data. @ShouwenW @Li_Li_666 nature.com/articles/s4159…

Happy to announce my next career step - I’ve launched my independent research lab at Dana Farber! If you are a trainee interested in ambitious projects at the intersection of chemical biology and cancer biology, please reach out! gibsonlab.org

Thrilled to share that our paper nature.com/articles/s4158… is featured in a fantastic Nature News & Views piece by @ThomasTueting! 🎉 Grateful for the spotlight on our research and its impact on understanding cancer immunology. nature.com/articles/d4158… 👀👉 rdcu.be/d3cRz

🐭First Telomere-to-Telomere sequence of a mouse genome!🐭 Professor Xiaochun Yu from the School of Life Sciences at Westlake University published a groundbreaking research paper today in Science. The research team utilized long-read third-generation sequencing technology to…

Several years in the making (and aging), @Xueqian_Zhuang 's study on aging is out today @Nature. She finds, surprisingly, that aging suppresses tumorigenesis and stemness in the lung by promoting a functional iron insufficiency in the alveolar epithelium. nature.com/articles/s4158…

Our perspective in @ScienceMagazine on #Ferroptosis—#disease perils and #therapeutic promise science.org/doi/10.1126/sc… written for a general audience -- not too technical. Congrats to authors @ashleybrown015 and Tal Hirschhorn! @Columbia

We are beyond excited to share our latest work on the role of PRDX6 in #ferroptosis out today in @MolecularCell and spearheaded by two exceptional postdocs in our lab, Junya and @eikan_em ! cell.com/molecular-cell…

Thrilled to share our paper now out @Nature delineating #plasticity during #CRC #metastasis, a fantastic collaboration led by @andrewrmoorman @elliebenitez11, and @f_cambuli from the @KarunaGaneshLab and @dana_per lab! nature.com/articles/s4158… rdcu.be/dYAVK. A 🧵