Yong Xiong Lab
@Xiongosome
We study host-viral interactions so our bodies can fight #coronaviruses and #HIV @Yale. RTs are not endorsements. FYI Yong doesn’t tweet, his students do!
Check out our paper showcasing the first structure of a fully modified human tRNA bound to amino acyl-tRNA synthetase. academic.oup.com/nar/article/53…
Our in situ virus studies elucidate a new target site for the potent HIV drug lenacapavir, alongside concurrent targeting by the maturation inhibitor bevirimat! biorxiv.org/content/10.110…
We're excited to announce a tenure-track or tenured faculty position in Cellular Biophysics and Structural Biology! We are especially excited to hear from candidates who develop in situ approaches in structural cell biology. Join us in MB&B! Apply now at apply.interfolio.com/151559
Our high-resolution (2.2 Å) in situ structural work reveals details of translational landscape, with various cofactors and antitumor drug/inhibitor, all directly within human cells! biorxiv.org/cgi/content/sh…
Aerial footage of the biophysics bbq! Thank you to all that helped organize and attended!
Congratulations to the poster and speaker winners for our biophysics and structural biology symposium! Including our very own Matt Cook!
The Biophysics and Structural biology symposium had a great turnout and great science!
Science socials hosted by the Xiong Lab are always loved 🫀🫀🫀. Great job to all the lab members who made home-cooked food, and thanks for coming!
Hope everyone had a happy holiday and is excited to get back to research 😅!
How many scientists does it take to install Yong's cryo-em monitor
Excited to announce our most recent paper is now published. We demonstrate that the mechanism of host translation inhibition is conserved across beta coronaviruses. doi.org/10.1016/j.celr…
Celebrating a joint lab birthday of Yuekang and Christian! Thanks to Matt for baking a wonderful cake :)
Congratulations to our very own Shravani Balaji for receiving the MB&B’s Excellence in Teaching Award!!!🎉🎉🎉
Snacks, donuts, and refreshments as some of us attend the CSHL Retroviruses meeting virtually! Great food paired with great science.
Remember, tomorrow at 9 am is the Annual Yale Biophysics and Structural Biology Symposium. Looking forward to many great talks, posters, and happy hour!
Xiong lab's latest research progress on HIV-1 nuclear import in Nature Structural & Molecular Biology and PNAS. @YaleMBB @YaleCellBio @YaleMed @YaleMicroPath doi.org/10.1073/pnas.2… nature.com/articles/s4159…
Researchers describe building blocks of HIV’s protective shell bit.ly/33vKYYJ @Xiongosome
And this month’s @Structure_CP cover art is from our collaborator Juan Perilla @UDelaware — an illustration of the capsid-binding factor MxB to accompany @sarahsmaga’s paper #SciArt
Also out today, Ivy’s companion paper in @CellReports with more detailed information about the #HIV cofactor FEZ1! sciencedirect.com/science/articl…
Big congrats to Brady and the ~Capsid Corps~ on their @cellhostmicrobe paper, out today! Brady et al spent years perfecting soluble capsid platforms that recapitulate different interfaces of the capsid lattice - a huge resource for #HIV biochemistry! authors.elsevier.com/c/1ZZEg6t8JEYt…