UofU3i

@UofU3i

The Immunology, Inflammation and Infectious Disease (3i) Initiative at @UofUHealth #biomedicalresearch #utah #science

Salt Lake City, UT

Joined March 2018

618Following

1KFollowers

UofU3i@UofU3i · 23 h

New 3i Investigator Article Alert!! A cannabinoid receptor 1 inverse agonist induces weight loss and reduces airway hyperresponsiveness in a mouse model of obese asthma pubmed.ncbi.nlm.nih.gov/40707031/?utm_…

UofU3i's tweet card. Most people with severe asthma have obesity. Metabolic dysfunction, often associated with obesity, is particularly associated with severe asthma. Mechanisms linking metabolic dysfunction with asthma,...

UofU3i@UofU3i · 23 h

New 3i Investigator Article Alert!! Sleep in disease: inflammation and chronic rhinosinusitis pubmed.ncbi.nlm.nih.gov/40703577/?utm_…

UofU3i's tweet card. Chronic rhinosinusitis (CRS) is a common inflammatory disorder that is associated with significant quality of life (QOL) impairment, including sleep dysfunction. There are multiple factors that have...

UofU3i@UofU3i · 23 h

New 3i Investigator Article Alert!! Microbiota Transplantation Among Patients Receiving Long-Term Care: The Sentinel REACT Nonrandomized Clinical Trial pubmed.ncbi.nlm.nih.gov/40705333/?utm_…

UofU3i's tweet card. ClinicalTrials.gov Identifier: NCT05780801.

UofU3i@UofU3i · Jul 24

New 3i Investigator Article Alert!! Inflammation and Immunomodulation in Cerebral X-linked Adrenoleukodystrophy: Review of Pathology and Interventions pubmed.ncbi.nlm.nih.gov/40696909/?utm_…

UofU3i's tweet card. ObjectivesMore than half of males with X-linked adrenoleukodystrophy (ALD) develop progressive, inflammatory cerebral demyelination (cerebral adrenoleukodystrophy). Treatment for cerebral adrenoleu...

UofU3i@UofU3i · Jul 24

New 3i Investigator Article Alert!! Integrating pulmonary and systemic transcriptomes to characterize lung injury after pediatric hematopoietic stem cell transplant pubmed.ncbi.nlm.nih.gov/40694427/?utm_…

UofU3i's tweet card. Hematopoietic stem cell transplantation (HCT) is a potentially life-saving therapy but can lead to lung injury due to chemoradiation toxicity, infection, and immune dysregulation. We previously...

UofU3i@UofU3i · Jul 24

New 3i Investigator Article Alert!! Optimizing Timing for Respiratory Syncytial Virus Prevention Interventions for Infants pubmed.ncbi.nlm.nih.gov/40699573/?utm_…

UofU3i's tweet card. In this economic evaluation of RSV prevention interventions, administration of MV in the first 4 months of and throughout the viral season could be cost-effective. Across the entire RSV season,...

UofU3i@UofU3i · Jul 23

New 3i Investigator Article Alert!! Mycoplasma hominis prosthetic valve infective endocarditis and endophthalmitis in a renal transplant recipient: a case report pubmed.ncbi.nlm.nih.gov/40692859/?utm_…

UofU3i's tweet card. Mycoplasma hominis is a rare cause of infective endocarditis, typically reported in immunocompetent patients following valve replacement. We report the first case of post-renal transplant prosthetic...

UofU3i@UofU3i · Jul 23

New 3i Investigator Article Alert!! Longterm kinetics of vibriocidal antibody responses after V. cholerae infection in the Democratic Republic of Congo pubmed.ncbi.nlm.nih.gov/40692446/?utm_…

UofU3i's tweet card. Interpretation of sero-epidemiology studies of cholera relies on knowledge of antibody kinetics, which are not well known in African populations. We performed vibriocidal antibody assays on 212 serum...

UofU3i@UofU3i · Jul 22

New 3i Investigator Article Alert!! Antimicrobial efficacy of on-label vs. hand-mixed irrigation solutions against S. aureus biofilms pubmed.ncbi.nlm.nih.gov/40688759/?utm_…

UofU3i's tweet card. Wound irrigation is routinely performed as part of the DAIR procedure and for hardware infections, yet the most effective irrigation solution for reducing bacterial bioburden is unknown. Clinicians...

UofU3i@UofU3i · Jul 22

A new #COVID19 pub from @UUtah researchers! Check it out: Vaccine Effectiveness Among 5- to 17-year-old Individuals with Prior SARS-CoV-2 Infection: An EHR-Based Target Trial Emulation Study from the RECOVER Project pubmed.ncbi.nlm.nih.gov/40630514/?utm_… @UofUResearch

UofU3i's tweet card. The effectiveness of COVID-19 vaccination in children and adolescents with prior SARS-CoV-2 infection remains unclear, particularly for Omicron subvariants. We evaluated vaccine effectiveness against...

UofU3i@UofU3i · Jul 22

New 3i Investigator Article Alert!! Delayed-onset Moraxella nonliquefaciens endophthalmitis following intravitreal injection pubmed.ncbi.nlm.nih.gov/40686765/?utm_…

UofU3i's tweet card. Moraxella species have been implicated in cases of endophthalmitis associated with glaucoma filtering surgery and trauma, but this report details a delayed-onset Moraxella nonliquefaciens-associated...

UofU3i@UofU3i · Jul 20

New 3i Investigator Article Alert!! Associations of serum and bronchoalveolar immunoglobulins with lung microbiota diversity, B-cell memory phenotypes, and COPD morbidity and exacerbations pubmed.ncbi.nlm.nih.gov/40682114/?utm_…

UofU3i's tweet card. These results demonstrate an association of low serum IgG with reduced lung bacterial diversity, a feature of dysbiosis that may predispose to exacerbation. Defining the role of Ig in specific...

UofU3i@UofU3i · Jul 20

New 3i Investigator Article Alert!! Epigenetic silencing of interleukin-10 by host-derived oxidized phospholipids supports a lethal inflammatory response to infections pubmed.ncbi.nlm.nih.gov/40680750/?utm_…

UofU3i's tweet card. Phagocytes initiate immunity to invading microorganisms by detecting pathogen-associated molecular patterns via pattern recognition receptors. Pathogen encounter and consequent activation of the...

UofU3i@UofU3i · Jul 20

A new #COVID19 pub from @UUtah researchers! Check it out: Unlocking efficiency in real-world collaborative studies: a multi-site international study with one-shot lossless GLMM algorithm pubmed.ncbi.nlm.nih.gov/40681761/?utm_… @UofUResearch

UofU3i's tweet card. The widespread adoption of real-world data has given rise to numerous healthcare-distributed research networks, but multi-site analyses still face administrative burdens and data privacy challenges....

UofU3i@UofU3i · Jul 19

New 3i Investigator Article Alert!! Diagnosis and Management of Community-acquired Pneumonia. An Official American Thoracic Society Clinical Practice Guideline pubmed.ncbi.nlm.nih.gov/40679934/?utm_…

UofU3i's tweet card. The panel formulated and provided the rationale for recommendations on selected diagnostic and treatment strategies for adult patients with CAP.

UofU3i@UofU3i · Jul 19

New 3i Investigator Article Alert!! Identifying Critical Evidence Gaps in Wound Closure and Incision Management After Total Hip Arthroplasty: Delphi Panel Insights pubmed.ncbi.nlm.nih.gov/40678786/?utm_…

UofU3i's tweet card. Addressing these evidence gaps is essential to improve THA wound care methods. Future studies should compare closure techniques and new technologies to develop more efficient patient-centered...

UofU3i@UofU3i · Jul 18

New 3i Investigator Article Alert!! Advancements in understanding the role of obesity in osteoarthritis pubmed.ncbi.nlm.nih.gov/40673791/?utm_…

UofU3i's tweet card. Obesity is a major risk factor for osteoarthritis (OA), yet the precise contribution to the pathogenesis of OA is still not fully known. Although traditionally viewed as a weight-induced joint...

UofU3i@UofU3i · Jul 18

New 3i Investigator Article Alert!! The social ambivalence and disease model: Childhood trauma as an antecedent factor linking spousal ambivalence to inflammation pubmed.ncbi.nlm.nih.gov/40673997/?utm_…

UofU3i's tweet card. These results highlight the potential role of childhood trauma as an antecedent factor linking spousal ambivalence to hs-CRP. It also highlights potential pathways that might be targeted for interv...

UofU3i@UofU3i · Jul 15

New 3i Investigator Article Alert!! The Effect of Medicaid Managed Long-Term Services and Supports Spending on Nursing Home Care Quality in the United States pubmed.ncbi.nlm.nih.gov/40659054/?utm_…

UofU3i's tweet card. This study highlights how capitation rates positively influence care quality in nursing homes within the MLTSS context. The findings provide valuable insights for policymakers, health care administ...

UofU3i@UofU3i · Jul 15

New 3i Investigator Article Alert!! Increased Caregiver Interaction with the NICU Environment during Medication Administration May Contribute to Higher Infection Rates: A Pilot Observational Study pubmed.ncbi.nlm.nih.gov/40659044/?utm_…

UofU3i's tweet card. After nearly 3 years without a single central line-associated bloodstream infection (CLABSI), our neonatal intensive care unit (NICU) experienced a significant rise in CLABSI rates beginning in 2019....