TRANSLATE Trial
@TranslateTrial
RCT of TRUS vs LATP in primary diagnosis of prostate cancer. Sponsor @UniOfOxford. Funder @NIHRresearch. Trial unit @SITU_Oxford + @OCTRUctu. @NDSurgicalSci.
Trial CI @LabBryant delighted to read out #TRANSLATE_Trial results during #GameChanger session @Uroweb #EAU25 Thank you to all our investigators, recruiting sites, funders @NIHRresearch and, most importantly, our 1126 pts! thelancet.com/journals/lanon… Trial visual abstract below ⬇️


V grateful to @declangmurphy for his excellent, provocative & thoughtful "discussant" response to #TRANSLATE_Trial read-out by @LabBryant @LambAlastair @NDSurgicalSci @sashi_kommu @DrBenEddy @HideYamaUrol @Mattpingchao Watch it again in full here ⬇️ youtu.be/O4-wKmhza6Y
Finishing up #BAUS25 on the main stage our Clinical Lecturer @Connor_Urol presenting an update on two major UK prostate randomised controlled trial published this year #TRANSLATE #NEUROSAFE
Co-Chief Investigator @LabBryant outlines #TRANSLATE_TRIAL journey during @NDSurgicalSci #SurgicalGrandRounds this morning. @OCTRUctu @SITU_Oxford #SGR #Oxford_Urology




Mind meld with @TranslateTrial ⭐️ @LambAlastair @GuysUrology @QMUL @gpalapa2 @UMichUrology Nesbit #AUA25 reception. Planning the individual patient data meta-analysis for TP vs TR prostate biopsy @VickersBiostats @UrologyMSK
🚨 Just published in @TheLancetOncol! 📌 The #TRANSLATEtrial shows that LATP biopsy detects more clinically significant prostate cancer than TRUS (60.1% vs 54.4%; OR 1.32, p=0.031). 🧬 Lower infection risk 📊 Comparable complications 😖 Slightly more pain reported 🔗…
A study led by Oxford University has found a new way of performing prostate biopsies which is more effective at diagnosing prostate cancer. This work was spearheaded from NDS and conducted in @SITU_Oxford. Congratulations to the whole team👏 Read more ➡️ nds.ox.ac.uk/news/new-biops…
Consultant Urological Surgeon, Mr Hide Yamamoto (@hideyamaurol) from @MTWnhs and researchers from around the UK taking part in @TranslateTrial have found a new way of performing prostate biopsies is more effective at diagnosing prostate cancer. Read more: ow.ly/Mt2e50Vu2N5
GU Cast celebrates these two excellent clinical trials run in the @NHS supported by @NIHRresearch, both presented in plenary #EAU25, both published @TheLancetOncol @TranslateTrial @neurosafeproof 😀👏 @RenuEapen @BAUSurology
Results from the #NIHRfunded @TranslateTrial, published in the @TheLancetOncol provide new evidence regarding the two currently available common techniques for prostate biopsy, to better inform urologists and patients of the relative trade-offs between the two techniques.
Researchers from around the UK, led by Oxford University, have found that a new way of performing prostate biopsies is better at diagnosing prostate cancer, but takes longer to perform and is more painful for patients. Find out more ⬇️
Such a treat to celebrate with friends after presentation/publication of #TRANSLATE_Trial!! Well done everyone 👏 🍾🥂 #EAU25 @TranslateTrial
@TranslateTrial have published their results paper in The Lancet Oncology! Well done to all involved, and thank you to everyone who took part! 👏 Full paper: doi.org/10.1016/S1470-… News article summary: ox.ac.uk/news/2025-03-2… #ProstateCancerAwarenessMonth #OpenAccess
And here's the helpful commentary from the paper's esteemed reviewers! Also published in @TheLancetOncol today @BadarMian1 @KariTikkinen @adamkibel_uro #EAU25 thelancet.com/journals/lanon…
Congratulations to Oxford for completing the great TRANSLATE trial - long live TP biopsy! #EAU25 @TranslateTrial @LambAlastair @LabBryant
Breaking news pod - TRANSLATE trial just presented at #EAU25 with co-publication @TheLancetOncol @LabBryant @LambAlastair @TranslateTrial. Discussant @declangmurphy Deep dive on GU Cast just released youtu.be/QdWlFy2zrHU?si…
Excited to announce #TRANSLATE_Trial outcomes will read out at 10am Sun 23rd March in eURO Auditorium 1 #EAU25, Madrid Synchronous embargoed publication in @TheLancetOncol #LATPvsTRUS - we'll finally give you the answer Hope to see you there! @GUCast @LabBryant @LambAlastair

@TranslateTrial results @Uroweb EAU Madrid, 10am Sunday 23/3/25, Green Area eURO Auditorium 1. #LATP v #TRUS prostate biopsy, n=1126; 1ry outcome GGG>=2 cancer detection, 2ry = infection, other complications, cost-effectiveness; @LambAlastair @LabBryant @NDSurgicalSci @OCTRUctu
Thanks Matt! Was fun to write. Good to see it out and about. bjui-journals.onlinelibrary.wiley.com/doi/10.1111/bj… Re @LondonProstate1 comment - we wrote this before the follow-up @JAMAOnc so at that point infection was middle. @LabBryant @TranslateTrial
Just out in @bmj_latest, our "Uncertainties in Practice" article on #LATP vs #TRUS We highlight evidence so far, discordance between recommendations (@Uroweb vs @NICEComms vs @AmerUrological) & need for nuance (!) Not long now until @TranslateTrial... bmj.com/content/387/bm…👈
Last list on fellowship with @LambAlastair at @OUHospitals NHS Trust . HUGE thank you to Prof. Alastair Lamb, privilege to learn from you. TY for the invaluable masterclass in robot assisted radical prostatectomy. GRATITUDE to excellent scrub team members too! #SurgicalMentor