Theofanis Karaletsos
@Tkaraletsos
Head of AI @cziscience | http://Achira.ai | probabilistic and deep ML
Autoregressive models are too restrictive by forcing a fixed generation order, while masked diffusion is wasteful as it fits all possible orders. Can our model dynamically decide the next position to generate based on context? Learn more in our ICML paper arxiv.org/abs/2503.05979
Proud to share a big step toward building systems that help us simulate and predict the behavior of cells! GREmLN is a graph-based transformer model, designed to reason across biological data by embedding gene regulatory network architecture directly into its attention…
Fun write up by @ElliotHershberg on virtual cells
What Are Virtual Cells? centuryofbio.com/p/virtual-cell Two months ago, I started working on an essay to answer this question. The goal was to cover a few of the recent research results. Simple as that! Instead, I went down a rabbit hole exploring ideas around cellular simulation…
ICML 25 paper on variational guidance for diffusion models accepted Happy to share that our diffusion model guidance paper with @farrinsofian, @kpandey008, @felixDrRelax, and @StephanMandt on casting control for guidance as variational inference with auxiliary variables was…
🚀 News! Our recent #ICML2025 paper “Variational Control for Guidance in Diffusion Models” introduces a simple yet powerful method for guidance in diffusion models — and it doesn’t need model retraining or extra networks. 📄 Paper: arxiv.org/abs/2502.03686 💻 Code:…
Is this the greek version of Wrexham? Go @kostascrypto !
⚽️ Just backed a small football team from the birthplace of Aristotle in 🇬🇷 ... in a lower division today, but aiming for the national leagues, and hence why they do need modernization! With support from Sui, we’re bringing blockchain to the pitch: on-chain stats, NFTs,…
TranscriptFormer is a new AI model trained on millions of cells from 12 different species, spanning 1.5 billion years of evolution. It is a concise, interactive representation of this massive amount of data. Preprint: bit.ly/3YnxzjB Model: bit.ly/42AvbbS
Meet the judges & mentors for the Tahoe Deep Dive Hackathon & thanks @awscloud for offering the prize: $25K AWS credits to winner, 10K & 5K to 2nd and 3rd. Deadline to apply: Apr 4th, details in 🧵. A short DM with @ClementDelangue; and now an entire community coming together!
We're launching ACHIRA, a newco DIMENSION cofounded alongside @jchodera & @tkaraletsos. We're building foundation simulation models for the smallest, atomic-level resolution units of the universe. Assembling here: achira.ai