Talking CRISPR

Alright, admitted, I was intimidated by twitter's name change, and haven't been online before now. But since then, this happened!!! Big congrats to @SarahCamara94 #dav604 and @rafapinilla92 uncovering these unbelievable RNA based anti-#CRISPR s

Such a pleasure talking with @JacquesHughes about our findings. Big thanks to the @NaturePodcast team for having me! Tune in to the episode to hear our conversation🦠🎙️ nature.com/articles/d4158…

Dr. Evelien Adriaenssens wrote this beautiful opinion piece about our recent baby virus study. She is the chair of the bacteriophage subcommittee within the ICTV, so her opinion matters. And I'm humbled to say the least. @COPSAC_com @JPI_HDHL #phage

1/n Excited to share a story on prokaryotic Argonautes (pAgos)!! 🎉 Here, we describe a short pAgo that mediates robust antiviral protection!🛡️ But how!? 🧵👇 biorxiv.org/content/10.110…

Very excited to see our story online in @NAR_Open!🎉 We found plasmids in nature carry a fascinating diversity of CRISPR-Cas🌈🤯 We characterized their abundance, diversity, distribution & investigated their CRISPR contents to infer their function(s)!! academic.oup.com/nar/advance-ar…

The baby #phage #asthma story is on the front page of politiken.dk now

Phages in babies protect against future disease! Check out our latest paper in @NatureMedicine nature.com/articles/s4159… @COPSAC_com

MindBlow on @VsauceTwo is featuring our infant gut virome story (skip to 0:39) 🤓😃😎 youtu.be/sxi0-Y_RWsU?t=… #virome #omics #YouTube @JPI_HDHL @COPSAC_com @NatureMicrobiol @novonordiskfond

New database of 10.000 infant gut phages to map your baby reads against: copsac.com/earlyvir/f1y/f… copsac.com/earlyvir/f1y/t… copsac.com/earlyvir/f1y/a… @JPI_HDHL @COPSAC_com @novonordiskfond #omics #phage #virome

Looks like phage diversity is higher in babies than adults. Why? Check out the story behind the paper. It's a four-minute read. microbiologycommunity.nature.com/posts/infant-g… @COPSAC_com @JPI_HDHL @NatureMicrobiol #phage #CRISPR #virome @cristinalero @smoineau @stokholm_jakob @GormAnders @microUCPH

We found hundreds of viral families in baby diapers. Everything we found is online (copsac.com/earlyvir/f1y/f…). This project started all the way back in 2016. So excited that it's finally out! @COPSAC_com @JPI_HDHL #OpenScience #phage #CRISPR #virome #metagenome

@TCrispr lays out his brilliant paper on phages in childrens gut. I remember once thinking "Wow, we identified a handful of new viral families!". Shiraz and the rest of this group just found +100 new ones 🤯 Check out the brilliant online overview 👇 tiny.cc/aq76vz

The guts of healthy infants are alive with viral diversity @COPSAC_com @NatureMicrobiol nature.com/articles/s4156… #phage #CRISPR #microbiome #virus

Another defence system, guys: biorxiv.org/content/10.110… The prokaryotic argonaute recognises viruses using a guide RNA, then activates a transmembrane protein to depolarise the membrain and commit suicide. #antiviral #antiphage #archaea #CRISPR

Binning #viral / #phage genomes directly from #metagenomics data while automatically defining #viralpopulations across samples? Now you can using PHAMB - new tool to run on top of VAMB (or another binner)! Fantastic work led by @joachim from my group: biorxiv.org/content/10.110…