Suel Kee Kim
@Suelkee
Neuroscientist @YaleNeuro, Sestan Lab, Brain Development and Evolution, Human-Specific Features, Pluripotent Stem Cells, Human Variation
Conditions like autism, depression, and Alzheimer’s may begin before birth. New research shows that key genes are already active in the fetal brain—shaping development long before symptoms emerge. neurosciencenews.com/asd-genetics-n…
Could Mental Illness Begin Before You’re Born? A new study reveals that many genes associated with brain conditions—including autism, depression, schizophrenia, and Parkinson’s—are active during the earliest stages of fetal brain development. These genes begin influencing…
Linking alterations in precursor cells of #brain 🧠formation with the origin of #neuropsychiatricdiseases Joint work by @GRIB_Barcelona and @YaleNeuro, published in @NatureComms #TalentMAR #bioinformàtica @UPFBarcelona researchmar.net/news/742/linki…
Vinculen alteracions en les cèl·lules precursores de la formació del #cervell 🧠 amb l’origen de les #malaltiesneuropsiquiàtriques Treball conjunt del @GRIB_Barcelona amb @YaleNeuro, que publica @NatureComms #TalentMAR #bioinformàtica @UPFBarcelona researchmar.net/noticies/1367/…
🥳Congratulations to Xoel Mato, member of the neurogenomics group, for his first paper on @NatureComms and co-led by Gabriel Santpere and Nicola Micali! 🔗nature.com/articles/s4146… @HMar_research @the_prbb
Excited to share our latest work, Mato-Blanco et al., nature.com/articles/s4146…. Thanks to the incredible collaboration with Nicola Micali, Rakic lab, Sestan lab, Vaccarino lab @YaleNeuro, Santpere lab, @CarloColantuoni.
NEXT TUE: DDD seminar, July 8, 2025 @ 1PM Eastern US: Dr. Alessandro Vitriolo @AVitriolScience (Lab of Dr Giuseppe Testa @gtesta72) “Regulatory logic of human cortex evolution by combinatorial perturbations”. seminar info: carlocolantuoni.org/seminar [repost to spread the word]
Thrilled to present MIND! A model for how the sensorimotor–association axis of the neocortex develops. Huge thanks to the incredible multidisciplinary team who made this happen. biorxiv.org/content/10.110…
NEXT TUE: DDD seminar, June 10, 2025 @ 1PM Eastern US: Dr. Magdalena Sutcliffe (lab of Dr. @mad_lancaster) “Epigenetic restoration of differentiation competency via reversal of epiblast regionalisation”. seminar info: carlocolantuoni.org/seminar [repost to spread the word]
Excited to showcase as a co-first author our latest work "Adaptive Evolution of Gene Regulatory Networks in Mammalian Neocortical Neurons" biorxiv.org/content/10.110…
A team at @Yale used morphogen gradients to generate patterned brain #organoids! 🧫 Read the @CellStemCell article: bit.ly/4jZvPWH Listen to the analysis on our latest episode: bit.ly/4k0nXEm
Today in @Nature, we report a spatial single-cell atlas of human cortical development, revealing surprisingly early specification of human cortical layers and areas. We built an interactive browser to explore the spatial data: walshlab.org/research/corte… Paper link below👇
NEXT TUE: DDD seminar, May 6, 2025 @ 1PM Eastern US: Dr. Ron McKay “Origin and consequences of genetically distinct behaviors in human neural stem cells”. seminar info: carlocolantuoni.org/seminar [repost to spread the word]
NEXT TUE: DDD seminar, Apr. 1, 2025 @ 1PM Eastern US: Dr. Jason Stein @jsteinlab “Modeling genetics altering human cortical structure”. seminar info: carlocolantuoni.org/seminar [repost to spread the word]
NEXT TUE: DDD seminar, Mar. 11, 2025 @ 1PM Eastern US: Dr. @MartineTherrie4 (UC Davis) “Systematic interrogation of free fatty acid toxicity in neurodegenerative diseases”. seminar info: carlocolantuoni.org/seminar [repost to spread the word]
NEXT TUE: DDD seminar, Feb. 18, 2025 @ 1PM Eastern US: Dr. @kristenbrennand - “Using Stem Cells to Explore Gene x Environment Interactions Underlying Brain Disease”. seminar info: carlocolantuoni.org/seminar
Thrilled to share our latest paper from Sestan lab on the development of the claustro-amygdala complex is published in Nature nature.com/articles/s4158…. A big thank you to all our collaborators and mentors. @MarinaP63 @rkovner88 @kartikpattabir1 @DavidAndrijevic
NEXT TUE: DDD seminar, Jan. 14, 2025 @ 1PM Eastern US: Dr. @MartaP4lcantara (from @GosiaTrynka's group at the Wellcome Sanger Institute) “Linking neurodegeneration candidate genes to cellular function using pooled iPSC-derived microglia”. seminar info: carlocolantuoni.org/seminar
NEXT TUE: DDD seminar, Tue. Dec. 17, 2024 @ 1PM Eastern US: @MFWellsLab Dr. Michael Wells will speak on "Natural variation in gene expression and viral susceptibility revealed by neural progenitor cell villages": cell.com/cell-stem-cell…. seminar info: carlocolantuoni.org/seminar
How human brains got so big: our cells learned to handle the stress that comes with size nature.com/articles/d4158…