Structure

@Structure_CP

Structure is a monthly publication of @CellPressNews dedicated to research at the cutting edge of #structuralbiology. Tweets are by the Editors.

Cambridge, MA, USA

Joined August 2012

1KFollowing

7KFollowers

Structure@Structure_CP · Jul 25

Online now! Cross-species recognition of squirrel ACE2 by the receptor binding domains of SARS-CoV-2, RaTG13, PCoV-GD and PCoV-GX dlvr.it/TM6lpc

Structure_CP's tweet image. Online now! Cross-species recognition of squirrel ACE2 by the receptor binding domains of SARS-CoV-2, RaTG13, PCoV-GD and PCoV-GX dlvr.it/TM6lpc

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Structure@Structure_CP · Jul 25

Online now! Automated identification of small molecules in cryoelectron microscopy data with density- and energy-guided evaluation dlvr.it/TM6fxv

Structure_CP's tweet image. Online now! Automated identification of small molecules in cryoelectron microscopy data with density- and energy-guided evaluation dlvr.it/TM6fxv

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Structure@Structure_CP · Jul 25

Online now! EnsembleFlex: Protein structure ensemble analysis made easy dlvr.it/TM6WJl

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Structure@Structure_CP · Jul 24

Online now! Regulatory mechanisms of PP2A complex assembly driven by physicochemical differences in A-subunit isoforms dlvr.it/TM5SfC

Structure_CP's tweet card. Day et al. demonstrate that PP2A scaffold isoforms Aα and Aβ have different physicochemical properties. Cryo-EM analysis reveals Aβ′s more concave structure with disrupted B-subunit interactions....

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Structure@Structure_CP · Jul 22

Online now! Exploiting a rational β-strand insertion strategy and disulfide locking to mechanically manipulate domain-swapped protein structures dlvr.it/TM3KLQ

Structure_CP's tweet card. Ghanbarpour et al. show how an odd versus even number of amino acid insertions in the hinge region alters secondary protein structure by exploiting the basic principle of beta strand periodicity....

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Structure@Structure_CP · Jul 18

Online now! A structure-guided approach to predict MHC-I restriction of T cell receptors for public antigens dlvr.it/TM09N1

Structure_CP's tweet card. Gupta et al. mined structural data to pinpoint the 32 amino acids on human leukocyte antigens most often contacted by T cell receptors and used them to cluster 148 common alleles into 21 functional...

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Structure@Structure_CP · Jul 18

Online now! SeaMoon: From protein language models to continuous structural heterogeneity dlvr.it/TM01qv

Structure_CP's tweet card. Lombard et al. present SeaMoon, a method that predicts how proteins deform using only their amino acid sequences. Through a lightweight neural network on top of a protein language model, SeaMoon...

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Structure@Structure_CP · Jul 17

Online now! Geometry-aware template matching for cryo-electron tomograms in Dynamo dlvr.it/TLz8pC

Structure_CP's tweet card. Coray el al. describes a GPU-enabled module in Dynamo for the detection of repeating structures in a tomogram through template matching. It is built to exploit characteristic distributions of...

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Structure@Structure_CP · Jul 17

Online now! Accurate helical parameter estimation based on cylindrical unrolling dlvr.it/TLz0mV

Structure_CP's tweet card. Huang et al. present HELIS, a method for helical parameter estimation, where the helical structure is treated as a rolled two-dimensional crystal. HELIS enables the precise estimation of helical...

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Structure@Structure_CP · Jul 14

Online now! CryoEM-enabled visual proteomics reveals de novo structures of oligomeric protein complexes dlvr.it/TLvspK

Structure_CP's tweet card. Shen et al. apply and compare visual proteomics pipelines to anaerobically and aerobically prepared samples from the bacterium Azotobacter vinelandii. These pipelines reveal the identities and...

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Structure@Structure_CP · Jul 11

Online now! Structural basis for no retinal binding in flotillin-associated rhodopsins dlvr.it/TLsX0t

Structure_CP's tweet card. Kovalev et al. determined cryo-EM structures of a flotillin-associated rhodopsin (FAR) lacking retinal cofactor and its retinal-binding paralog, a classical light-driven proton pump from the same...

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Structure@Structure_CP · Jul 10

Online now! Structures of USP7 in active and inactive states bound to DNMT1 revealed by cryo-EM dlvr.it/TLrSPD

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Structure@Structure_CP · Jul 8

Online now! Structure of a type II SMC Wadjet complex from Neobacillus vireti dlvr.it/TLpNLP

Structure_CP's tweet card. Wadjet are SMC-based prokaryotic defense systems that cleave plasmid DNA. Roisné-Hamelin et al. reconstitute a type II Wadjet and demonstrate that it exhibits substrate selection and cleavage...

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Structure@Structure_CP · Jul 8

AI-guided cryo-EM analysis untangles uromodulin lattices that safeguard kidneys dlvr.it/TLpDHr

Structure_CP's tweet card. In this issue of Structure, Chang et al. combined deep-learning cryoelectron microscopy (cryo-EM) particle picking and heterogeneous refinement to obtain structures of human uromodulin filament...

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Structure@Structure_CP · Jul 8

Decoding the molecular choreography of colibactin: Structural insights into a genotoxic assembly line dlvr.it/TLp1wW