Sten Helmfrid 🇺🇦

Professor Brian Hughes on Medically Unexplained Symptoms: “It took GPs a median of just 12 seconds to decide that a patient’s symptoms were psychosomatic. In 50% of consultations, GPs had decided that symptoms were psychosomatic before the patients had even started talking.” →

The issue is not whether something is psychological or physical, but whether proposed interventions work. People with #MECFS have said, we don’t accept bad science such as biased trials or anecdotal evidence. We want evidence-based treatments that work! x.com/KH118118/statu…

Vink and Vink-Niese: “CBT and graded exercise therapy studies have proven that ME/CFS and long COVID are physical diseases, yet no one is aware of that.” frontiersin.org/journals/human…

#MECFS is a severe, neurological illness that affects tens of millions of people worldwide. People who want recognition. People who are waiting for help. People who want more and better research to be funded. Most of all: People who want their lives back! #MEAwarenessHour

#MECFS is a severely debilitating illness that leaves about 25% of the patients housebound. Did you know that the illness does not only affect the lives of the patients, but that the quality of life of partners and other family members also is severely impaired? #MEAwarenessHour

Good point! The bar for accepting bad science is much lower for biopsychosocial interventions than for pharmaceutical interventions. If a pharmaceutical company would use an RCT of the same quality as PACE to sell their stuff, there would be an outcry! x.com/sfadigacronica…

The biopsychosocial approach for #MECFS was first introduced in 1988. The best evidence that this paradigm doesn’t work is the so-called evidence they present for it. No single properly conducted RCT for 37 years, but anecdotal evidence, correlations, strongly biased trials etc.

Some researchers perpetuate the belief that #MECFS is psychogenic in nature. Did you know that many leading Universities now pursue biomedical research on ME/CFS and that many researchers accept the biological nature of the illness after reviewing the evidence? #MEAwarenessHour

Beentjes et al., comparison of traits for people with #MECFS and controls in UK Biobank data. Hundreds of traits differed between cases and controls, but single traits couldn’t distinguish case from control. The results cannot be explained by inactivity. embopress.org/doi/full/10.10…

Fluge et al., pilot study on subcutaneous anti-CD38 antibody daratumumab in moderate to severe #MECFS. For six responders of ten patients, mean SF-36 PF increased from 32.2 to 78.3. Low NK-cell count was significantly associated with lack of response. frontiersin.org/journals/medic…

#MECFS is a severe multi-system illness. There is currently no diagnostic test, but did you know that studies have shown abnormalities at a group level in the brain, the central and autonomous nervous system, the immune system, and the cellular energy production? #MEAwarenessHour

Professor Ron Davis, Stanford University: “If you get chronic fatigue syndrome or #MECFS, your life as you know it’s over. That is really sad, because it hits people at the prime of their life.” #MEAwarenessHour

ME is a neurological illness that affects tens of millions of people worldwide. Severe cases may be bedridden, unable to care for their basic needs, and sensitive to sound, light, and touch. Despite its severe nature, patients are often dismissed. #MEAwarenessHour

#MECFS is a severe, neurological illness that affects tens of millions of people worldwide. People who want recognition. People who are waiting for help. People who want more and better research to be funded. Most of all: People who want their lives back! #MEAwarenessHour

Hypothesis: #MECFS is a persistent, inappropriate, ‘neuroimmune hypervigilance’ mediated primarily by T lymphocyte-macrophage interaction but influenced by IgG antibody binding to the gamma interferon-inducible high affinity immunoglobulin receptor FcγRI. meassociation.org.uk/2025/05/prepri…

#MECFS is a severely debilitating multisystem illness that affected 10–30 million people worldwide before the pandemic—a number that likely has increased. A message to people in denial: The problem will not go away by being ignored. We urgently need research. #MEAwarenessHour