Ildus I. Ahmetov
@SportsGenomics
Reader in Genetics and Epigenetics @LJMUSportSci Sports genomics ∙ Talent ID ∙ Behavioural genomics ∙ Muscle ∙ Sarcopenia ∙ Obesity ∙ Nutrition ∙ Longevity
Delighted to see our paper published in @NatureComms! We identified EDA2R as the top gene linked to aging across all human tissues, acting as both a biomarker of inflammaging and a driver of aging. @LJMUSportSci nature.com/articles/s4146…
Multiplex detection of seven transgenes for human gene doping analysis (EPO, FST, GH1, IGF1, MSTN, VEGFA, VEGFD) nature.com/articles/s4159…
A novel method, RIP–qPCR, detects CRISPR–Cas9 gene editing in sport by targeting key genes including MSTN, ACTN3, EPOR, and EPO. link.springer.com/article/10.100…
Excited to share our new paper in Skeletal Muscle! We show that large Maf transcription factors can robustly induce MYH4, normally silent in humans. In human muscle, Mafa and Maf expression correlate with fast fiber content.doi.org/10.1186/s13395… #myotwitter
Building upon our previous study published in Cell Rep (10.1016/j.celrep.2023.112289), which identified large Mafs as essential regulators of type IIb myofiber specification in mice, this work extends our understanding to humans. biorxiv.org/cgi/content/sh… #Myotwitter @MYOTWlTTER
GWAS identifies 70 genetic variants linked to leisure, work, and home-time physical activity nature.com/articles/s4158…
Polygenic prediction of cardiorespiratory fitness: The HUNT Study medrxiv.org/content/10.110…
Uncovering the Molecular Landscape of Physical Activity: Proteomic Insights from the UK Biobank medrxiv.org/content/10.110…
A 1.9–3.3% increase in global muscle mass in humans is associated with a 4.1 ± 5.8% reduction in fat mass in studies lasting from 2 weeks to 3 years. link.springer.com/article/10.100…
Elite rowers have a markedly higher prevalence and incidence of atrial fibrillation (AF), particularly those with a high AF polygenic risk score. academic.oup.com/eurheartj/adva…
Switch-like genes, showing "on" or "off" expression in different people, include 473 linked to cancer, immune, metabolic, and skin diseases. Only 8.5% are universally switch-like across all tissues; 91.5% are tissue-specific. nature.com/articles/s4146…
Over the past 40 years, the gap in physical activity between those with high and low genetic predisposition to be active has doubled, increasing from 10.7 minutes per week in 1984 to 21.4 minutes in 2019. bmjopensem.bmj.com/content/11/2/e…
We are pleased to share that the final version of our latest review, focusing on the role of MyoD in adult skeletal muscle, has now been published in @AJPCellPhys journals.physiology.org/doi/full/10.11…
Biology of Sport has a new Impact Factor: 5.0 (Q1)! Ranked 7th out of 133 journals in its category. Huge congratulations to all authors, editors, and reviewers — your work is invaluable! JCI: 2.33, placing BiolSport 3rd in Sport Science.
Individuals with a lower genetic predisposition to obesity tend to experience greater weight loss when treated with semaglutide medrxiv.org/content/10.110…
Scientists discover 'speed gene' of fastest humans ljmu.ac.uk/about-us/news/… @BiolSport