Christian Speck
@Speck_Lab
Professor at Imperial researching DNA replication & epigenetics using integrative biology approaches. Love collaborative work + interest in drug screening.
To all postdocs. Are you ready to start your semi-independent career? The BBSRC Fellowship call is open. We could host you if you work in the area of DNA replication/chromatin/cancer and like to use protein biochemistry, genomics, cryo-EM, AlphaFold, MD… tinyurl.com/bdd2yv8z
PREPRINT OUT! Cell cycle regulation is not limited to conserved TFs. Select young TFs (29-105myo) 1) regulate cell cycle genes and 2) set the #ReplicationTiming of gene clusters. Brainchild of @ForeyRomain and @PulverCyril. doi.org/10.1101/2024.1…
Great science, fantastic opportunity to learn, and an exciting project. I strongly recommend applying.
I have two PhD positions available in my group next year! These projects are looking at how disordered regions alter protein dynamics. One is through the Yorkshire BBSRC DTP, advertisement to come, but more information can be found here: whiterose-mechanisticbiology-dtp.ac.uk/yorkshire-bios…
I have two PhD positions available in my group next year! These projects are looking at how disordered regions alter protein dynamics. One is through the Yorkshire BBSRC DTP, advertisement to come, but more information can be found here: whiterose-mechanisticbiology-dtp.ac.uk/yorkshire-bios…
Great kickoff for the EMBO EMBL Replication symposium with amazing structural and functional insights into initiation, elongation and histone recycling 🧬♻️ @TyeBik @CostaLabCrick @BleichertLab @Speck_Lab Chistol @Lopes_Lab Méchali @YardimciLab 🙌 #EESReplication @EMBLEvents
One week left to apply for a cryoEM facility manager position @SussexUni If you want to be an integral part of the growing community of researchers imaging the molecules of life in human disease then this is the job for you! jobs.sussex.ac.uk/job/0fc71993-6…
Another chance to join us at Birmingham. This time open also to ECRs and junior independent researchers. Genome biology is one of the priority areas (as is cancer and RNA biology). Have a look 😀. Get in touch 😀
We're delighted to announce the next cycle of recruitment for our 125th Anniversary Fellows and Chairs is now open! If you are an academic with a strong portfolio of global-leading research, we want to hear from you. Check out our vacancies and apply now: fellowsandchairs.birmingham.ac.uk/?utm_campaign=…
BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
Does anyone I know on twitter have any old akta purifiers hanging around I can take some parts off?
Here is the link to the Colab, let us know if you have any problems or you have a hard target our pipeline cannot design against! We want to keep improving it and community feedback is very important 🙏🏻💻 colab.research.google.com/github/martinp…
Then I thank @befcorreia for his awesome guidance! The pipeline is based on and uses components from the fantastic work from @sokrypton ColabDesign, @RosettaCommons PyRosetta, and @JustasDauparas ProteinMPNN.
Closing on the 13th of October is a Postdoctoral Researcher Scientist role in the Development and Transcriptional Control Group headed by @metzisv lms.mrc.ac.uk/vacancies/mrc-…
Interested in how cells make decisions? Want to build new tools and model embryonic development using ESCs? Come join us @MRC_LMS! We have a #postdoc position open in the area of gene regulation, stem cells and mouse development. See how to apply here: lms.mrc.ac.uk/vacancies/mrc-…
Make publication ready figures from your #AlphaFold PAE files. Works on multimer and AlphaFold 3 files. Customize colors and export as an SVG for editing in illustrator! thecodingbiologist.com/tools/pae.html
🧬A new study in @NatureComms by @Speck_Lab @MRC_LMS has shown how DNA helicases are equally distributed across the yeast #genome, ensuring accurate #DNAReplication. This could have implications for cancer & age-related diseases in the future. 👉lms.mrc.ac.uk/discovery-of-f…
I am very happy to share our recent publication @NatureComms about origin licensing in budding yeast. Had a blast working with @Speck_Lab, @morvorenlowen, @KorbinianLiebl et al. at @MRC_LMS and @imperialcollege. Read about it here and 👇 1/3: rdcu.be/dRTAZ