Søren Grubb

🐭🧠 #PrecapillarySphincters (PS) at the #arteriole–#capillary junction rapidly dilate ~30% in seconds during #SensoryStimulation—regulating #capillary #BloodFlow dynamically. Here we investigated whether they protect downstream microvessels during abrupt #BloodPressure surges 🧵

Love seeing how active #SciSky is in sharing knowledge and getting together starter packs, so I put together a collection I have so far...yes they are in alphabetical order and yes I am bit ridiculous 😀add any I missed or repost with yours. Still hoping for a #neuropathology…

We are excited to report: Cerebral blood flow is modulated by astrocytic cAMP elevation independently of IP3R2-mediated Ca2+ signaling in mice Vittani et al. PNAS (2025) pnas.org/doi/10.1073/pn…

📢Breaking: New Open🔓 Access Publication Brain precapillary sphincters modulate myogenic tone in adult and aged mice by Christina L. Fjorbak & Søren Grubb (@SorenGrubb) et al. rdcu.be/esYVm #aging #pericyte #Hypertension #precapillarysphincter #autoregulation…

Where the grass is greener and the sky is bluer, join me on Bluesky (bsky.app/profile/soreng…): nature.com/articles/d4158…

Many #neurovascular #scientists are migrating to #bluesky right now. If you want to kickstart your presence on Bluesky, you can use #starterpacks to selectively follow scientists that share your interests. I have made a thread with starter packs I follow: bsky.app/profile/soreng…

You can find me on Bluesky: @sorengrubb.bsky.social

🧠🔬 Exciting #HotTopic: microglial "plugs" found at blood vessel contacts in the brain! This opens a new path to understand how microglia interact with the vasculature in health and disease. Don't miss it: journals.sagepub.com/doi/full/10.11… #JCBFMhome #ISCBFM #BrainResearch

Awesome!!! This seems like a job for the @AllenInstitute to scale up to a whole mouse brain! 🤩

🔥 Exotic! Wild🦁💓