Simge Kelekçi
@Simgekelekci
Epigenetics, genomics, DNA methylation @DKFZ | Alumni @METU_ODTU-GENE'(BSc)-CHEM'(BSc) | @kocuniversity (MSc) | Posting on @Postdocp
More than happy to share my first first-author review now published in @FrontCellDevBio ! links.email.frontiersin.org/ls/click?upn=D… Big thanks to my PI @Tamer_Onder and my colleagues @CimConan @denizugurlucime
Happy to be part of this work on dual DNMT1 and G9A inhibitor! Check it out our paper on biorxiv: biorxiv.org/cgi/content/sh…
Happy to be part of this amazing work!
I'm excited to share our preprint "Pyjacker identifies enhancer hijacking events in acute myeloid leukemia including MNX1 activation via deletion 7q": doi.org/10.1101/2024.0…. This is my main PhD work and a massive collaborative effort. 🧵👇
I've just uploaded an overview video for figeno: youtube.com/watch?v=h1cBeX…. Check it out if you want to plot sequencing data along genomic coordinates: bigwig, HiC, nanopore (with base modifications), WGS...
Thrilled to introduce epiCHAOS! Another nice work from our division!
I'm excited to share our preprint "Pyjacker identifies enhancer hijacking events in acute myeloid leukemia including MNX1 activation via deletion 7q": doi.org/10.1101/2024.0…. This is my main PhD work and a massive collaborative effort. 🧵👇
✔ Very useful tool developed by my colleague @EtienneSollier ! 👍 Highly recommended if you need to draw excellent plots !
Introducing figeno, my visualization software for (epi)genomics🧬🎨. Supports many data types (bigwig, HiC, @nanopore data with base modifications, WGS...) and is easy to use with a GUI. Can visualize multiple regions (e.g. for breakpoints). github.com/CompEpigen/fig…
Highly recommended opportunity with a perfect supervisor and amazing mentor!
Contact me if interested in this post-doc opportunity in our lab. For more info also see scl.ku.edu.tr
Happy to be a part of the organisation team for this exiciting event! Join us on the 12th of January,2024 to learn more about career opportunities after PhD/Postdoc 😉 linkedin.com/posts/dkfz-car…
Epigenetisch wirkende Medikamente ermöglichen, dass Bereiche des Erbguts abgelesen werden, die vorher blockiert waren. Das führt zur Bildung neuer mRNA und neuer Proteine, die das Immunsystem beim Erkennen von Krebszellen unterstützen könnten. @uktuebingen t1p.de/994hd
Our lab is on fire 🔥 A very nice work about the activation of LTR12C elements upon epigenetic inhibitors treatment! And be ready to hear more work about epigenetic inhibitors and their effect on transcription from our lab ;) @NatureComms @Nature @dkfz nature.com/articles/s4146…
Very happy that this is out! Thanks to the work of many passionate scientists from Academia, Industry and Clinics, to the generosity of #COPDpatients. High-resolution #transcriptomic and #epigenetic profiling ids novel #COPD regulators #Multiomics #humanLungFibroblasts
We completed the first whole genome #DNAmethylation profiles in #copd, revealing potential disease regulators 👇. High‐resolution transcriptomic and epigenetic profiling identifies novel regulators of COPD embopress.org/doi/10.15252/e… #epigenetics, #wgbs 🧵
Delighted to share our story about enhancer hijacking event! First contributing article of my PhD @DKFZ . Many more to come hopefully 😉 @Nature nature.com/articles/s4137…
LOSEV - Earthquake Relief Aid in Turkey on @globalgiving goto.gg/58617 @ustunezer @hulya_unver @losev1998 #earthquake #earthquakeinturkey #cancer
Please reach out to Turkish and Syrian students and co-workers around you. They are not OK. We are not OK.
Hala haber yok. 2 koca deprem oldu, 24 saatten fazla gecti. Butun sehir enkaz icinde, calismalarin basladigi çok az yer var. Bu kadar deprem yasamış bir coğrafyada, milyonlarca kisinin yasadigi sehirlerin merkezine bile 24 saatte ulaşılamıyorsa yazıklar olsun! #hatay #AFADhatay
#Hatay #defne Armutlu mah. Gunduz Cd. Timur Sk. Kaya Apt. yikildi. Teyzem, eniştem ve cocuklar dahil bircok apartman sakini enkaz altında. #AFAD ekipleri yogun enkaz yüzünden mahalleye giremiyor. Yoldaki enkazı bile temizlemek icin destege ihtiyac var. #deprem #Ahbap_Hatay
#Hatay #defne Armutlu mah. Gunduz Cd. Timur Sk. Kaya Apt. yikildi. Teyzem, eniştem ve cocuklar dahil bircok apartman sakini enkaz altında. #AFAD ekipleri yogun enkaz yüzünden mahalleye giremiyor. Yoldaki enkazı bile temizlemek icin destege ihtiyac var. #deprem #Ahbap_Hatay
Last chance to apply as group leader in computational cancer epigenomics, a great position in an extremely motivated Division with great students and colleagues, headed by Prof. Christoph Plass at the DKFZ, check it out, link below jobs.dkfz.de/en/jobs/135078…
More than happy to contribute this work! Happy to see it now online @stemcellreports !!
Happy to share out latest paper, out today @stemcellreports. We discover BRD9 as a chromatin-related barrier to somatic cell reprogramming cell.com/stem-cell-repo…
Happy Pluripotency day! #Oct4 Find a picture of iPSCs-derived HSPCs producing red blood cells😲😲 in our lab.

I've attended 'Spetses Summer School in Cancer Epigenetics'.Wonderful lectures, breath-taking views, and excellent posters!Students are the firsts to ask questions which I think that distinguishes this summer school from others. @intercept_mds #spetses2022



