Sanjeev Sethi
@SethiRenalPath
Professor, Pathology, Mayo Clinic, MN. ๐ฏ clinical. Renal pathology. Use X to teach, clinical info changed=protect confidentiality. Love dogs. Views are my own.
Antigens in membranous nephropathy: discovery and clinical implications nature.com/articles/s4158โฆ
Mayo Clinic Laboratories' new mass spectrometry assay requires just one small tissue sample to identify 13 antigens known to cause membranous nephropathy. Learn more about this one-stop test. @SethiRenalPath bit.ly/4k1loks
๐ฃ๐ข โ๐๐ซ๐ฌ๐ญ ๐๐๐ฒ๐จ ๐๐ฅ๐ข๐ง๐ข๐ - ๐๐๐ฅ๐ฅ ๐โ๐๐๐๐ซ๐จ๐ง ๐๐๐๐๐๐๐๐๐๐ ๐๐๐๐๐๐โ save the dates 5-6 Sep Barcelona 2025. Register to [emailย protected] organized by @MayoClinicNeph @NefrologiaVH @vallhebron @HerrmannMd @OriolBestard @fervenzafernan1
Sorry I accidentally deleted the original post while trying to answer some questions. Iโm still a novice with X ๐ Take home message: small ~3% of PLA2R negative MN cases by routine IF are PLA2R positive by LMD/MS. kidney-international.org/article/S0085-โฆ
๐ ERA Congress 2025 โ Vienna ๐ง Focus: Membranous Nephropathy An inspiring session chaired by Ingeborg Bajema & Michael Rudnicki. Sanjeev Sethi speaking on MGN. From anti-PLA2R to the promise of epitope-specific assays, from pathology to patient: the conversation is evolving.โฆ
Gian Marco- It was wonderful having you train with us. Seven months went by quickly-you were at every renal pathology sign out with me. You never missed my weekend sign out taking every opportunity to learn. Wish you all the best for your future. Safe travels to Bologna ๐ฎ๐น

Many people tried to prevent publication of this data. Puts to rest claims that we donโt have hard-end points in MN treated with RTX! Long-term Outcome of Adult Patients with Membranous Nephropathy treated with Rituximab. - Kidney International Reports kireports.org/article/S2468-โฆ
This Dx often not the mind of nephrologist- always surprised by Dx Fibrillary Glomerulonephritis LM: Membranoproliferative GN IF: IgG 3+, polyclonal=3+ kappa & lambda EM: fibrillary deposits DNAJB9 positive, Congo red negative 65 yr obese lady, hematuria & proteinuria. Cr 2




A lovely sketch made by Dr. Estela Mas Rodenas. Look carefully and you can see the @MayoClinic in the picture. Thank you very much for the beautiful sketch. It was wonderful having you train with us. Safe travels back to Mallorca. @EstelaNefro


