CRISP_SCIENCE

@ScienceCrisp

RIKEN (CODATA, WDCM ...) - NIG (CODATA, DDBJ/CIB, WDCM, OECD BRC, GBIF, JST BIRD, TPRP ...) - FREE

Tokyo (Web site in Japanese)

Joined January 2017

348Following

2KFollowers

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CRISP_SCIENCE@ScienceCrisp · 8 m

REVIEW "CRISPR/Cas9 for achieving postintervention HIV control" Moso MA, Roche M, Coeval PM, Lewin SR. Curr Opin HIV AIDS. 2025-07-16. doi.org/10.1097/COH.00… PROTECT, EXCISE OR MODIFY and ATTACK; delivery modalities

CRISP_SCIENCE@ScienceCrisp · 5 m

"Split crRNA-Mediated Regulation of CRISPR-Cas12a Enables Construction of Biochemical Circuits for Sensitive Molecular Diagnostics" Xu X [..] Li Y. Anal Chem. 2025-07-21. doi.org/10.1021/acs.an… CREST (CRISPR Reactions Elicited by Split en-crRNA Transcription)

ScienceCrisp's tweet card. The clustered regularly interspaced short palindromic repeat (CRISPR) system represents a fundamental tool for biotechnological applications. However, the ability to engineer intrinsic components of...

CRISP_SCIENCE@ScienceCrisp · 5 m

"Identification of a key nucleotide influencing Cas12a crRNA activity for universal photo-controlled CRISPR diagnostics" Tian T [..] Zhou X. Nat Commun. 2025-07-21. doi.org/10.1038/s41467… … a four-nucleotide segment within the Cas12a crRNA direct repeat (DR) region …

ScienceCrisp's tweet image. "Identification of a key nucleotide influencing Cas12a crRNA activity for universal photo-controlled CRISPR diagnostics"
Tian T [..] Zhou X. Nat Commun. 2025-07-21.
doi.org/10.1038/s41467…
… a four-nucleotide segment within the Cas12a crRNA direct repeat (DR) region …

CRISP_SCIENCE@ScienceCrisp · 8 m

“Genome-wide CRISPR/Cas9 screening identifies PTGR2 as a potential therapeutic target for sunitinib resistance in clear cell renal cell carcinoma” Chang W [..] Wang W, Shang P, Sue Z. Sci Rep. 2025-07-19. doi.org/10.1038/s41598…

ScienceCrisp's tweet card. Scientific Reports - Genome-wide CRISPR/Cas9 screening identifies PTGR2 as a potential therapeutic target for sunitinib resistance in clear cell renal cell carcinoma

CRISP_SCIENCE@ScienceCrisp · 23 h

"An unbiased genomewide screen uncovers 7 genes that drive hematopoietic stem cell fate from mouse embryonic stem cells" Palma LG [..] Bigas A. Blood 2025-07-17. doi.org/10.1182/blood.… CRISPRa screen

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CRISP_SCIENCE@ScienceCrisp · 23 h

"Dynamic basis of supercoiling-dependent DNA interrogation by Cas12a via R-loop intermediates" Aris KDP [..] Bryant Z. Nat Commun. 2025-03-26. doi.org/10.1038/s41467… Twist measurement based on gold rotor bead tracking (AuRBT) #CRISPR

ScienceCrisp's tweet image. "Dynamic basis of supercoiling-dependent DNA interrogation by Cas12a via R-loop intermediates"
Aris KDP [..] Bryant Z. Nat Commun. 2025-03-26.
doi.org/10.1038/s41467…
Twist measurement based on gold rotor bead tracking (AuRBT)
#CRISPR

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CRISP_SCIENCE@ScienceCrisp · 23 h

"Identification of Epigenetic Regulators of Vascular Calcification with a CRISPR-Based Screen” Lian Y [..] Huang H. J Am Soc Nephrol. 2025-07-18. doi.org/10.1681/ASN.00…

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CRISP_SCIENCE@ScienceCrisp · 23 h

"Rationally Designed TadA-Derived Cytosine Editors Enable Context-Independent Zebrafish Genome Editing" Qin W [..] Varshney GK. Adv Sci. 2025-07-20. doi.org/10.1002/advs.2… ＃CRISPR (SpRYCas9n); zTadCBE

ScienceCrisp's tweet image. "Rationally Designed TadA-Derived Cytosine Editors Enable Context-Independent Zebrafish Genome Editing"
Qin W [..] Varshney GK. Adv Sci. 2025-07-20.
doi.org/10.1002/advs.2…
＃CRISPR (SpRYCas9n); zTadCBE

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CRISP_SCIENCE@ScienceCrisp · 23 h

"Identification of β4GALNT2 as an anti-hPIV3 factor through genome-wide CRISPR/Cas9 library screening" Wu X [..] de Haan CAM. Emerg Mirobes Infect. 2025-07-16/Dec. doi.org/10.1080/222217…

ScienceCrisp's tweet card. Human respirovirus 3 (also known as human parainfluenza virus 3; hPIV3) is a major cause of severe acute respiratory infections in vulnerable populations. Here we conducted a genome-wide CRISPR/Cas...

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CRISP_SCIENCE@ScienceCrisp · Jul 25

Review "Off-target Effects in CRISPR-Cas Genome Editing for Human Therapeutics: Progress and Challenges" Kalter N, Fuster-García C, Silva A et al. Mol Ther Nucleic Acids. 2025-07-17. doi.org/10.1016/j.omtn…

ScienceCrisp's tweet image. Review "Off-target Effects in CRISPR-Cas Genome Editing for Human Therapeutics: Progress and Challenges"
Kalter N, Fuster-García C, Silva A et al.
Mol Ther Nucleic Acids. 2025-07-17. doi.org/10.1016/j.omtn…

136

CRISP_SCIENCE@ScienceCrisp · Jul 25

"Early Postnatal Expression Mitigates Immune Responses to Cas9 in the Murine Central Nervous System” Duba-Kiss R, Hampson DR. Mol Ther Methods Clin Dev. 2025-07-17. doi.org/10.1016/j.omtm… #CRISPR

ScienceCrisp's tweet image. "Early Postnatal Expression Mitigates Immune Responses to Cas9 in the Murine Central Nervous System”
Duba-Kiss R, Hampson DR.
Mol Ther Methods Clin Dev. 2025-07-17.
doi.org/10.1016/j.omtm…
#CRISPR

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CRISP_SCIENCE@ScienceCrisp · Jul 25

"Engineering an Escherichia coli with Performance-Enhanced Switch Utilizing CRISPR-Cas9 System as Living Quorum Quencher for Biofilm Formation Inhibition" Zhou J [..] Wang C. Environ Res. 2025-07-17. doi.org/10.1016/j.envr…

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