Saarang Deshpande, MD
@SR_DeshpandeMD
Aspiring classical hematologist, fellow @DanaFarber @MassGenBrigham | @Penn @cwrusom @Cornell alum | social medicine & equity | not medical advice
Introducing my classical hematology reading list! docs.google.com/document/d/1wC… Over the past few years, I’ve noticed that the best physicians I’ve worked with have a keen understanding of how key papers from this era of proliferating research apply to complex clinical cases.
Our review out today on immune TTP
Immune thrombotic thrombocytopenic purpura (iTTP) is an immune-mediated disorder characterized by thrombocytopenia and microangiopathic hemolytic anemia. Learn more in this Review. ja.ma/3ZsypvR
Great work to @isabellemahe1 and the team! The findings appear to remain true on my (napkin math) meta-analysis of the randomized trials on this topic, including EVE and the cancer subgroups of EINSTEIN CHOICE and RENOVE
Prof. @isabellemahe1 presents API-CAT at #ACC2025, published in @NEJM Extended anticoagulation with reduced-dose apixaban is noninferior to full-dose for preventing recurrent VTE, with less clinically relevant bleeding 🩸in patients with cancer. nejm.org/doi/full/10.10…
In this BJH In a Nutshell article, Drs. Song and Al-Samkari bring you up to date on the status of research in chemotherapy-induced thrombocytopenia and how to treat this common problem with TPO-RAs. buff.ly/H4QU0fo @HannyAlSamkari @andrewbsong
Another great episode of the foremost hematology journal club podcast, Don't Just Read the Abstract, on TPE-free TTP management: open.spotify.com/episode/1CipC7… A brief thread on this topic from a few months ago: x.com/SR_DeshpandeMD…
**NEW EPISODE** Pleased to release the latest episode of Don't Just Read the Abstract with @PipNicolson. We discuss Kuhne et al.'s study in @BloodJournal on the treatment of TTP without the use of plasma exchange. There will be a follow-up episode with an author interview.