Statistical Physics of Cells and Genomes
@SPCGgroup
Twitter page of the scientific group Statistical Physics of Cells and Genomes (SPCG), Principal Investigator (PI) Marco Cosentino Lagomarsino (MCL).
This is officially our X social network. We moved to @spcggroup.bsky.social. So long, and thanks for all the fish🐬!
🚨 Could treating less and resting more be the key to smarter #cancer therapies? 💡💊 Our latest preprint shows how math models can shape intermittent therapies to exploit cancer #persisters and achieve better outcomes. 🔗 read here: biorxiv.org/content/10.110… @SPCGgroup @Simopompei
We are grateful to @AIRC_it for funding our project! In the next 5 years we will work on growth inhibition, arrested cells and cancer persisters.
Lots of fun and lots of science with @LucaCiandrini lab @micalilab and our guests @AshleyLNord @biancaSclavi @mlaenoc @pcicuta @GabrielNeurohr
Very proud of our students at the first IICII Summer School in Quantitative Biology. ifom.eu/events/2024-su… 6/6 student groups performed successful Luria-Delbrück fluctuation tests with excellent data. Presentations tomorrow! @ictpnews @ICGEB @IFOMresearch @institut_curie
New KITP Program! #MICROECO26 Coarse-graining Microbial Ecology: from Genes to Physiological Strategies to Communities across Environments Dates: 5/18/26-6/18/26 kitp.ucsb.edu/activities/mic…
Apply!
New KITP Program! #MICROECO26 Coarse-graining Microbial Ecology: from Genes to Physiological Strategies to Communities across Environments Dates: 5/18/26-6/18/26 kitp.ucsb.edu/activities/mic…
📢Two postdoc positions open📢 ictp.it/opportunity/po… Deadline Aug 16 Happy to chat if you have questions -- Thread about Trieste/@ictpnews here x.com/jacrickets/sta…
Trieste is a beautiful coastal city in northern Italy at the crossroads of cultures 🇮🇹🇸🇮🇭🇷🇦🇹 with a very high quality of life. Info about the city of Trieste discover-trieste.it intrieste.com 2/5
We can't wait for the next chapter! science.org/doi/10.1126/sc…
Direct single-cell observation of a key Escherichia coli cell-cycle oscillator | Science Advances Our paper on the coupling of the oscillations in DnaA activity and expression with cell size is now published ! A great ongoing collaboration with @SPCGgroup.
Now out on @ScienceAdvances science.org/doi/10.1126/sc…
@SPCGgroup preprint: we follow for the first time the DnaA cell-cycle oscillator in single E. coli cells, and find that activity+dosage oscillations do not behave as initiations- with @IlariaIuliani @biancaSclavi , bioRxiv: biorxiv.org/content/10.110…
Recorded talks are here youtube.com/playlist?list=…
It was fun to listen to great science, discuss with top scientists, see old friends (and also not bad to eat great food, and enjoy great sights) @polstnet @ictpnews @jacrickets
It was fun to listen to great science, discuss with top scientists, see old friends (and also not bad to eat great food, and enjoy great sights) @polstnet @ictpnews @jacrickets
@SPCGgroup paper, now out on PNAS pnas.org/doi/10.1073/pn… Total messenger levels affect cell growth by modulating free ribosomes. work by @LCalabreBiophys in collaboration with @LucaCiandrini
Now out on @softmatter : a miraculously simple mean-field theory of single-polymer collapse by crowders, thanks to work from Quentin Chaboche @VittoreScolari, Marjolein Dijkstra and her group. pubs.rsc.org/en/content/art…
Great work (and great cover) by our friends @marcogherardi and @OsellaMatteo
Our paper on the non-monotonic training dynamics of representations in deep learning is on the cover of Nature Machine Intelligence! @NatMachIntell nature.com/natmachintell/…
Two PhD positions are available in our institute for interdisciplinary projects. See link below to see the project proposed by myself and @LucaCiandrini on quantitative biology and math. modeling of bacteria's adaptation. If interested don't hesitate to contact us. #PhDposition
The i-Bio international PhD Program 2024 is opening 2 PhD positions in co-supervision to work at the interface between biology and other scientific disciplines. Application are open until April 15, 2024 ibio.sorbonne-universite.fr/2024-phd-progr…
In the Spotlight: Cancer Clones Cooperate to Alleviate Growth Barriers in Critical #CancerProgression Transitions— @cmaley discusses a recent @ScienceAdvances paper from @KM_Havas et al. bit.ly/3sgXuwA #OnlineFirst
Congratulations *Dr* Ludo, @LCalabreBiophys for a great PhD defense! xkcd.com/1403
New @SPCGgroup preprint, a growth model that links nutrient sensing to ribosomal allocation predicts damped oscillatory response to environment changes. @rossana88191832 , with @jacrickets and @LCalabreBiophys biorxiv.org/content/10.110…
New @SPCGgroup paper on @PLOSCompBiol: Metacommunity structure preserves genome diversity in the presence of gene-specific selective sweeps. @Simopompei @jacrickets @joshuasweitz journals.plos.org/ploscompbiol/a…