Sumanth Prabhu, MD
@SDPrabhuMD
Cardiologist and physician-scientist. Heart failure and cardio-immunology researcher. Husband and father. Guitar music enthusiast. All tweets my own.
Thoughtful editorial perspective by Ebin Johny and @ParthaDuttaLab on the importance of the spleen in healing the heart after myocardial infarction. #cardiosplenic axis! Circulation ahajournals.org/doi/full/10.11…
Thank you @StavrosStavrak1 and the entire the cardiology group at OU for the invitation and the honor of presenting the Lazzara lecture. Appreciated the great conversations!
🫀Second Annual Ralph Lazzara Lecture at OU today 🫀Featured speaker Dr. Sumanth Prabhu, Chief Cardiology Division at Wash U 🫀Outstanding discussion on “Inflammation & HF Revisited” @OUCollegeofMed @DrDave01 @ubcardio @StavrosStavrak1 @JasonKatzMD @ShashankSinhaMD…
At @BarnesJewish time was of the essence when a patient under the care of WashU Medicine doctors Amit Pawale, MD, and Joel Schilling, MD, PhD, @WashUCardiology was admitted with heart failure. The patient needed a heart transplant — and soon. Read more > l8r.it/XdTj
@CircRes Interorgan Crosstalk in #HF & #Cardiometabolic Diseases Compendium CV, #Kidney, #Liver, & Metabolic Interactions in #HF: Breaking Down Silos ahajrnls.org/3ZtHfJQ by @rsyf2 @josephahill @FaiezZANNAD @ShahzebKhanMD @JenHoCardiology @leahkosyakovsky et al
Very glad to see our recent work in press at @CircAHA . Alternatively activated macrophages driven by IL-4 signaling sustain a parainflammatory response in the failing heart. Kudos to @QiongxinWang for her tireless work on this study
CD206⁺IL-4Rα⁺ macrophages proliferate and drive adverse LV remodeling via FIZZ1-mediated fibrosis. IL-4Rα deletion or silencing reverses remodeling and improves function. A novel therapeutic target in ischemic cardiomyopathy ahajournals.org/doi/full/10.11…
Thrilled to have our work characterizing the cardiosplenic axis after MI in press @MAIwustl @WashUCardiology @WashUDeptMed
A specialized spleen macrophage population—expressing the markers CD169 and Tim4—mobilizes after MI to drive repair, clear neutrophils & reduce HF risk. A new frontier in cardioprotection via the cardiosplenic axis. @ssbansal_pshvi @SDPrabhuMD ahajournals.org/doi/full/10.11…
What constitutes the parainflammatory response in heart failure? Our latest work shows the importance of alternatively activated macrophages in driving heart failure ahajournals.org/doi/10.1161/CI… #cardioimmunology @QiongxinWang
Excited to share our latest published work showing that marginal metallophilic macrophages from the spleen traffic to the heart and are required for cardiac repair after myocardial infarction. ahajournals.org/doi/pdf/10.116… This raises the possibility of therapeutic splenic…
A pleasure to host @pnatarajanmd as the 2025 Guller Family Lecturer at @WashUCardiology @WashUDeptMed!Outstanding overview of preventive cardiology, and the power of genome wide approaches to uncover new CV risk predictors. @GullerKeith
Smith-Oliver reception at #AHA2024 for @WashUCardiology ! Catching up with old friends. And new ones.
That’s a wrap on #BCVS24! Thanks to everyone who helped take this meeting to a whole new level. Let’s meet again at #BCVS25.
Closing Remarks for an amazing #BCVS24! Huge thanks to @FarahSheikhLab and @SDPrabhuMD See you all at #BCVS25
Congratulations to cardio-oncologist Dr. Jesus Jimenez of @WashUCardiology on winning the Outstanding Early Career Investigator Award at #BCVS24! Superb work on the effects of newer pathways for checkpoint inhibition on the heart. @LavineLab @AHAScience @FarahSheikhLab…
#BCVS2024 in full swing. Outstanding talks and posters with cutting edge science, collaboration and collegiality. A personal honor to recognize @IntMedAbel as the 2024 Keynote Speaker - he has been an inspiration to many! @FarahSheikhLab @AHAScience @JonPHeart @WashUCardiology…
So proud of our graduating @WUCardioFellows ! We can’t wait to see what you accomplish going forward. And with great appreciation for @akates1 dedication and superb leadership of the @WashUCardiology fellowship training program for the last 16 years. @WUDeptMedicine
@WUCardioFellows Farewell Celebration! My final graduating class! Such a wonderful group. Could not be prouder! @k_wongMD @RajaZaghlol @nicholasrarnold @SDPrabhuMD @prathakker @WashUCardiology
Honored to work on this focused review on the #cardioimmunology of #heartfailure with @PilarAlcaidePhD, @kallikourdis, and @RamonaE_91. Take a look!
@CircRes The Interface Between #Cardioimmunology, #Myocardial Health, and #Disease Compendium Alert! Myocardial #Inflammation in #HeartFailure with Reduced & Preserved #EF ahajrnls.org/4ecEiDc Authored by Drs. @PilarAlcaidePhD @kallikourdis @RamonaE_9 & @SDPrabhuMD
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Check this out-many great articles on cardiac immunology - quest editors - @ImmunoCardioLab,@DrCihakovaD,@ChristophMaack and Sumanth D. Prabhu. Interface Between Cardioimmunology, Myocardial Health, and Disease: A Compendium | Circulation Research (ahajournals.org)
Congratulations to Sam Jordan @RentschlerLab @WashUCardiology on a terrific scientific presentation @SarnoffCardio meeting!
Congratulations to Sam Jordan for a truly fantastic talk at the Sarnoff meeting in SF demonstrating epigenetic changes in myocytes after cardiac radiotherapy. It has been a true pleasure to have Sam in the lab, he is a star!!!