Rakyan Lab
@Rakyan_lab
Lab at the Blizard Institute, QMUL, working on gene-environment interactions and their impact on health and disease in humans and other model organisms.
New research in @CellGenomics led by @Rakyan_lab, @evans1_d and collaborator @evans1_d suggests that people with more copies of ribosomal DNA have higher risks of developing disease. Research funded by @Barts_Charity, @RosetreesT and @BBSRC. Find out more: qmul.ac.uk/media/news/202…
A new study, led by Vardhman Rakyan and Francisco Rodriguez-Algarra from @blizard_inst in collaboration with David Evans from @UQ_News, suggests genetic disposition to disease can be found in previously understudied areas of the #genome.
Research led by @QMUL suggests that people with more copies of #rDNA have higher risks of developing inflammation and diseases during their lifetimes. qmul.ac.uk/media/news/202…
Analysis of previously unstudied areas of the human genome suggests people with more copies of ribosomal DNA have higher risks of developing disease. 🔗 Read more: bit.ly/3QJSkCa @evans1_d
Just in case anyone is interested, we won't be using X anymore. You can find us on B*u*S*y! Several new paper alerts from the lab!
Check out this study in @ScienceAdvances by @deMendoza_Alex team, they discovered "Genomic incorporation of giant viruses is regulated by DNA methylation in unicellular eukaryotes. This bridges epigenetic regulation with deep eukaryotic evolution" science.org/doi/10.1126/sc…
Congratulations to Eleonora Adami @Ele_Adami (brushandpipette.com) for winning £250 Amazon voucher for our new logo design competition for our new centre. Also, thank you, everyone, for sending their logo designs.
You are pleased to announce that Philipp Voigt (Babraham Institute) will speak at the @QMULepigenetics seminar series. Title "Decoding Bivalency: Mechanisms of Poising at Bivalent Gene Promoters" 28th June, 15:30 BST in person at @blizard_inst or online qmulepigenetics.com/webinars
🧵Excited to share our latest work, where we investigated how plants use DNA methylation to adapt to naturally fluctuating light regimes. Work led by the amazing @RobynAEmm and co-lead with @DrTracyLawson. great collab with @bechtis. biorxiv.org/content/10.110… @ResearchEssex 1/n
I´m thrilled to see our #LRGASP paper published in @naturemethods today. This is the work of many to benchmark long-read methods for transcriptomics, and a must-read paper for those using lrRNA-seq. Special thnks to @FJPardoPalacios and @TheBrooksLab (1/6) rdcu.be/dJ9ev
Looks like interesting work, but unfortunately completely neglected work by @PradeepMadapura's team, who last year demonstrated that LINE-1s act as distal regulatory elements: nature.com/articles/s4159…
This position is now re-advertised until June 16th. Please share or apply!
We have a 2y postdoc position open in my group. The profile is quite broad, from bioinformatics to molecular biology. If you are interested in giant virus endogenization, EvoDevo, epigenetics and evolution, do apply and gent in touch. Please RT. Details: qmul.ac.uk/jobs/vacancies…
This Sunday, June 2nd, I'll be at #eshg2024 in Berlin presenting poster about this. If you're around and want to have a chat, come see me at poster P17.072.A! Feedback extremely welcome ☺️☺️
New paper alert! The RNA ribosomal components are so essential that they appear as tons of back to back copies in the genome, which makes them really hard to analyse, so have been mostly ignored. But does it matter how many copies one has? A thread (1/9) cell.com/cell-genomics/…
QMUL Epigenetics 'Design a Logo' competition! We are relaunching as the QMUL Centre for Epigenetics. Design a new logo for us & win a £250 prize! All details 👉qmulepigenetics.com/logocomp Deadline is 6pm GMT, June 6, 2024 and the competition is open to all. please RT
Quantifying stochasticity in the ageing DNA methylome - comment on the 3 recent @NatureAging papers nature.com/articles/s4358… Viewable link here - rdcu.be/dH6Nv @qmulepigenetics #epigenetics #DNAmethylation #ageing #aging
Forgot to say I'll be at the @Londonomics_net symposium this next Monday (May, 20th) giving a short talk about this work, in case you want to chat about it :)
New paper alert! The RNA ribosomal components are so essential that they appear as tons of back to back copies in the genome, which makes them really hard to analyse, so have been mostly ignored. But does it matter how many copies one has? A thread (1/9) cell.com/cell-genomics/…
Ribosomal DNA Copy Number Levels Linked to Kidney Function, Inflammation in UK Biobank genomeweb.com/sequencing/rib…