🔬 R-loop

Genome-wide mapping of native co-localized G4s and R-loops in living cells dlvr.it/T7qmbh

Head trauma impairs HPA-axis functions by increased R-loop structure and shortens telomeres dlvr.it/T7xWMp

Functional conservation and divergence of Arabidopsis VENOSA4 and human SAMHD1 in DNA repair dlvr.it/T7gWjW

Machine learning-inferred and energy landscape-guided analyses reveal kinetic determinants of CRISPR/Cas9 gene editing dlvr.it/T6KqTy

NSUN2 Facilitates DICER Cleavage of DNA Damage-Associated R-Loops to Promote Repair dlvr.it/T6Gkvt

p53 restores the silencing of activated L1 Transposons dlvr.it/T5YTr0

ANP32E drives vulnerability to ATR inhibitors by inducing R-loops-dependent Transcription Replication Conflicts in Triple Negative Breast Cancer dlvr.it/T4lKsJ

G-quadruplex formation in GCK and TM6SF2 are targets for differential DNA methylation in metabolic dysfunction-associated fatty liver disease and type II diabetes mellitus patients dlvr.it/T4fVFT

Structural insight into bacterial co-transcriptional translation initiation dlvr.it/T4SWfL

YTHDC1 cooperates with the THO complex to prevent RNA damage-induced DNA breaks dlvr.it/T45HhB

Human immunodeficiency virus-1 induces and targets host genomic R-loops for viral genome integration dlvr.it/T3lWD3

Senataxin modulates resistance to cisplatin through an R-loop mediated mechanism in HPV-associated Head and Neck Squamous Cell Carcinoma dlvr.it/T367v9

GATAD2B containing NuRD complex drives R-loop dependent chromatin boundary formation at double strand breaks dlvr.it/T31Kzr

Tetrameric INTS6-SOSS1 complex facilitates DNA:RNA hybrid autoregulation at double-strand breaks dlvr.it/T30pMX

R-Loop Functions in Brca1-Associated Mammary Tumorigenesis dlvr.it/T2sMj6

The Impact of Mismatches Within the RNA: DNA Hybrid in the Transposon-Encoded Type I-F CRISPR-Cas System dlvr.it/T2DGjy

Engineered minimal type I CRISPR-Cas system for transcriptional activation and base editing in human cells dlvr.it/T1yBfL

Ewing Sarcoma Related protein 1 recognizes R-loops by binding DNA forks dlvr.it/T1gnzG

PSIP1/LEDGF reduces R-loops at transcription sites to maintain genome integrity dlvr.it/T18h3Q

TDP-43 chronic deficiency leads to dysregulation of transposable elements and gene expression by affecting R-loop and 5hmC crosstalk dlvr.it/T14xXr