Mehdi Jafarnejad
@RNAnomad
Principal Investigator @QubPGJCCR & @QUBelfast Everything RNA, little bit of other things....
We have a new preprint, led by PhD student Patric & (former) postdoc @PariN39103649, reporting a chordate-specific mechanism linking codon usage to mRNA translation/stability, mediated by 2 prologue RBPs ZC3H7A/B. Huge thanks to amazing collaborators! biorxiv.org/content/10.110…
We are very proud of our new preprint revealing #alphaviruses induces cellular #RNA #degradation via XRN1 and the decapping complex to feed viral #replication with nucleotides. Thanks to the whole team and collaborators for the fantastic work. biorxiv.org/content/10.110…
Excited to share the story of protein synthesis linked with drug resistance. See you tomorrow. :) Thanks @BiochemSoc @QubPGJCCR @RNAnomad
Register for our next webinar on 26 June! Deep dive into the exciting use of native mass spectrometry to uncover BiP molecular chaperone function and how Ribosome Quality Control can be a hidden ally of cancer cells against chemotherapy. Sign up today: ow.ly/jiKB50WeseR
We have a competitive PhD studentship in my lab to study the role of mRNA translation and quality control mechanisms in cellular response to anti-cancer treatments in AML. Please share with your network and if interested apply through the link below. findaphd.com/phds/project/i…
very much looking forward to this exciting seminar.
Join us for a PGJCCR Seminar with Prof Reuven Agami from @NKI_nl on “Causes and consequences of amino acid ‘Substitutants’ in cancer”. Hosted by @RNAnomad, everyone welcome & free to attend! Thu 13 March, 1pm, in MBC Lecture Theatre 2.
Only a few days left to apply to the PGJCCR #SummerResearchProgramme! Find out more here: qub.ac.uk/research-centr…
The Newton International Fellowships for this year are now open for applications! If you're a non-UK scientist & interested in RNA biology, feel free to reach out to discuss the possibility of joining my lab. Check the link below for more details. royalsociety.org/grants/newton-…
Just over two weeks left to apply for the PGJCCR #SummerResearchProgramme! Learn more about how you could spend your summer alongside researchers working at the cutting edge of #CancerResearch: qub.ac.uk/research-centr…
10 days left to submit your abstract for the #Epigenetics2025 conference, organized by @GenSocUK We’ve put together a fantastic scientific program, and Northern Ireland is a wonderful destination to explore.
Are you an undergraduate student wondering how to spend your summer in an exciting and career-enhancing way? Consider joining our summer research program! If you’re not an undergraduate student but know someone who is, please share this opportunity with them.
Applications for the PGJCCR #SummerResearchProgramme are now open! Learn more about what we offer and how you can join us this summer here: qub.ac.uk/research-centr…
How do DNA viruses co-opt the host cell translation machinery to repress the cGAS/STING response? I am glad you asked and I think we have at least part of the answer. Check out our brand new paper @PNASNews. Grateful to the funders, specially @BBSRC. @QubPGJCCR, @QUBelfast .
Congrats to our PhD student @Reesej786 on his exciting new work in @PNASnews. Reese and team show that 4EHP manipulates the antiviral response against DNA viruses by affecting translation of the DNA sensor protein cGAS. pnas.org/doi/abs/10.107…
The HBOF facility now offers standardized assays for molecular, cellular and in early 2025 physiological analysis of human stem cell-derived brain organoids. Fill in the submission form to find out more and to work with us. gkogkaslab.com/brain-organoids
Mark your calendar: we are excited to open registration for the Epigenetics-2025 International Conference, taking place in Belfast April 2025. We have an exceptional lineup of speakers and many opportunities for oral and poster presentations. @GenSocUK my.genetics.org.uk/item.php?event…
Elated to share our new discovery that explores how cancer cells escapes from anti-cancer drug 5-FU-induced toxicity. How cancer cell responds to survive? 1/n
Can 5-FU induce ribosome collisions? Could RQC mitigates the 5-FU cytotoxicity? Find the answers in our latest paper in @NAR_Open, led by @The_Chaturjey. Grateful to @acmedsci @royalsociety & our collaborators for their support. @QubPGJCCR, @QUBelfast academic.oup.com/nar/article/do…
Can 5-FU induce ribosome collisions? Could RQC mitigates the 5-FU cytotoxicity? Find the answers in our latest paper in @NAR_Open, led by @The_Chaturjey. Grateful to @acmedsci @royalsociety & our collaborators for their support. @QubPGJCCR, @QUBelfast academic.oup.com/nar/article/do…
Don't miss this folks.
Delighted to announce the next (hybrid) event of the All-Ireland RNA club: December 6th, organised by @QUBelfast members. Free registration and all welcome. Abstract submission by PhD students encouraged! @RNASociety @lexogen go.qub.ac.uk/RNAclubAutumn2…
🚨 Check out our new preprint “An intrinsically disordered RNA-binding region provides local target selectivity and is essential for LARP6 function”, out now on bioRxiv: biorxiv.org/content/10.110… A fun joint project with Conte’s lab @KingsCollegeLon. @QMBCI @BiochemOxford (1/10)
FOUR-YEAR INTERNATIONAL PhD PROGRAMME (International Students): Find the research project that you think is most relevant to you, and apply now: Deadline: 31 August 2024 qub.ac.uk/Study/postgrad…
FOUR-YEAR INTERNATIONAL PhD PROGRAMME (International Students): Take a look at our list of available research projects, and apply now. Deadline: 31 August 2024 qub.ac.uk/Study/postgrad…
After taking the coveted first place at the PGJCCR Summer Research Programme Poster Presentation, Daniel Hunter took a moment to share his experiences of working with us these past 8 weeks. Congrats again!