William Harvey Research Institute
@QMULWHRI
Multidisciplinary research institute devoted to therapeutic innovation in cardiovascular, inflammatory, and endocrine diseases. Part of @QMUL @QMULBartsTheLon
Our new paper is now published in @NatureMedicine ! This study presents a new multi-ancestry polygenic score developed using genetic data from over 5 million individuals. #genetics #obesity #sciencenews @QMUL
@QMULWHRI @CCPMG_TEAM @CCMN_London Physiological Significance of Endothelial M3 Muscarinic Receptors During Exercise | Circulation Research ahajournals.org/doi/10.1161/CI…
What a day - @uk_biobank now scanned 100,000 - when we dreamed about this back in 2009 I was not sure this was really possible. Grateful for the opportunity to co-lead the heart MRI part. @QMULBartsTheLon @HDR_UK #WHYCMR bbc.co.uk/news/articles/…
Huge congratulations to Dunja Aksentijevic, Professor of Cardiovascular Physiology and Metabolism @QMUL, on delivering a brilliant inaugural lecture last night: ‘Fuelling the heart: A metabolic tale of risk, resilience and repair’. @dunjaaks @QMULBartsTheLon


Thrilled to see Prof. Mike Murphy @Mito_Redox recognized at the @QMULWHRI Research Day! His groundbreaking work in mitochondrial biology has shaped the field & inspired so many. Grateful for his mentorship over the years. And what a moment seeing these two scientific giants meet!
A team finds that the #chemokine CXCL12 can support the production of #RedBloodCells in mice, suggesting that this pathway could be investigated for the treatment of disorders related to red blood cells. @stevenduke @GutjahrJulia @QMULWHRI scim.ag/446wONU
Although chemokines are known for their role in cell migration, new work in mice shows that CXCL12 also promotes the differentiation of #erythroblasts by promoting CXCR4 signaling and activity in the nucleus. @stevenduke @GutjahrJulia @QMULWHRI scim.ag/446wONU
New Paper🚨 @NatRevCardiol "Mechano-energetic uncoupling in heart failure"explores how disrupted interactions between cardiac mechanics and mitochondrial energetics drive #HF @EU_METAHEART 🙌🏻 @QMULWHRI nature.com/articles/s4156…
science.org/doi/10.1126/sc… We describe the hitherto overlooked expression of CXCR4 in erythroblasts, which do not migrate in response to CXCR4 ligation by CXCL12. Instead, CXCR4 localises to the nucleus and mediates alternative responses in erythroblast maturation and enucleation
🚨 We're hiring a #Postdoc!🚨 Exciting opportunity to work on inflammation, macrophage biology, & atherosclerosis in central London. Join our dynamic team @QMULWHRI! 🌍 🔗 Details: shorturl.at/pU1Rb 📩 [email protected] #AcademicTwitter #PostdocJobs
Exciting news! 📢 QMUL is hosting an area at the Tower Hamlets Family Hubs Fun Day and at the Centre of the Cell Science Fun Day! Join us by hosting your own stall or activity. Engage with local families, make a difference, and have fun! Find out more 👉 qmul.ac.uk/publicengageme…
Registration & abstract submissions are OPEN for @BSCResearch #BSCR2025 at William Harvey Research Institute, @QMULBartsTheLon QMUL! @QMULWHRI @TheBHF Programme & info: bscr.org/meetings/bscr2…
We are delighted to be hosting the 2025 @BSCResearch Autumn Meeting at William Harvey Research Institute @QMUL @QMULBartsTheLon 🗓️3-4 September 2025 Registration and abstract submissions are now open! 🔗lnkd.in/e2x5qtRr #BSCR2025

Are you a doctor with 3+ years' experience ready to advance your academic career? Join our DClin programme with flexible study, NHS placements & research skills training. 📅Webinar: 17 July, 9am UK 🔗Register: events.teams.microsoft.com/event/26d68ddb…

🚨T2D in 🚺 worsens STEMI outcomes beyond door-to-balloon delays & mirrors the HFpEF cardiometabolic phenotype in female db/db mice. Sex-specific strategies are urgently needed! Congrats to study co-leads @1blueivy @megan_e_young @BioMedCentral @QMULWHRI doi.org/10.1186/s12933…
It was a pleasure to contribute to this elegant study decipehring new metabolic mechanism in #diabetic 🫀. Huge congrats @Heatherlab_ox @CircRes 🥂@TheBHF @QMULWHRI
🚨New from our group in @CircRes We identify a FoxO1-zDHHC4-CD36 S-acylation axis driving metabolic + contractile dysfunction in the diabetic heart. Blocking this pathway reprograms FA metabolism and improves heart function. Read more: 🔗 ahajournals.org/doi/full/10.11…