Princeton Neuroscience Institute

This groundbreaking research was co-led by @PrincetonNeuro’s @SebastianSeung: bit.ly/3RLXKfW

Excited to share a connectomics dataset of hippocampus CA3. Explore the dataset: pyr.ai Paper introducing the dataset and some of our discoveries: biorxiv.org/content/10.110…

Music is an incredibly powerful retrieval cue. What is the neural basis of music-evoked memory reactivation? And how does this reactivation relate to later memory? In our new study, we used Eternal Sunshine of the Spotless Mind to find out. biorxiv.org/content/10.110…

New paper led by @jay_neuro: Repetition of musical themes in Eternal Sunshine of the Spotless Mind reactivates memories of earlier scenes, and this neural reactivation correlates with subsequent memory for those scenes! Check out Jamal's thread below 👇

I’m very excited to share that I will join the University of Utah Department of Neurobiology as an Assistant Professor in Jan 2026!! 🎉🏔️🏜️ My lab will focus on body–brain interactions in learning & memory — how do signals from our internal organs remodel the brain & behavior?

Out today in @Nature: we show that individual neurons have diverse tuning to a decision variable computed by the entire population, revealing a unifying geometric principle for the encoding of sensory and dynamic cognitive variables. nature.com/articles/s4158…

When faced with the same evidence, people can arrive at different outcomes, especially when the decision is difficult. For instance, two different drivers in rush hour traffic see the same congested road, yet one might speed up to merge while another cautiously brakes. How the…

“Like a group of skiers descending a mountain, each [neuron] prefers a slightly different path, but all are shaped by the same slope,” says @Princeton’s @EngelTatiana on her lab’s new @Nature study of how the brain makes decisions. 📰: pni.princeton.edu/news/2025/all-…

🎓 Congratulations to the Neuroscience Class of 2025! At PNI’s Class Day, seniors received their certificates, shared their research, and celebrated with family, friends, and faculty 🧠 pni.princeton.edu/news/2025/grad…

For her senior thesis, Kajal Schiller '25 designed a computer simulation game to measure whether socioeconomic status might determine how likely people are to take advantage of resources that can help them solve problems. bit.ly/4kSPWGu

1/ Excited to share our recent work in #ICML2025, “A multi-region brain model to elucidate the role of hippocampus in spatially embedded decision-making”. 🎉 🔗 minzsiure.github.io/multiregion-br… Joint w/ @FieteGroup @jaedong_hwang, @brody_lab, @PrincetonNeuro ⬇️ 🧵 for key takeaways…

In our latest edition of “This paper changed my life,” Bradley Dickerson discusses how a 1940s fly neuroanatomy paper taught him how to think about circuits and behavior being greater than the sum of their parts. thetransmitter.org/this-paper-cha…

Nice story today in the @princetonian on the Chris Chang Lab and their work on “Metals, molecules, and medicine: chemical biology’s influence on health and sustainability.” Read it here: bit.ly/4miZzPw

A team of researchers has developed a precise map of the vision centers of a mouse brain, which promises to accelerate the study of normal brain function: seeing, storing and processing memories, and navigating complex environments. bit.ly/4jS63TX

New op-ed in @Nature: The Trump administration's assault on freedoms and the rule of law is an existential threat to US science. We urge scientists to speak out in defense of freedoms, not just funding. With Andrea Liu @Penn and Sidney Nagel of @UChicago nature.com/articles/d4158…

🎉Congrats to NEU undergraduate Jeffery Chen '25 and PNI grad student Serene Dhawan, who were both recognized for their outstanding ability to communicate complex science at @princetonideas 10th annual Princeton Research Day! pni.princeton.edu/news/2025/neur…

In 1981, @Princeton's @HopfieldJohn received an NSF grant (~$300K) for the, then, obscure field of artificial neural networks. Today, that research powers a multibillion dollar AI economy and earned him a Nobel Prize. npr.org/2025/05/08/nx-…

🎉 Congrats to PNI’s Jonathan Cohen, Tom Griffiths (@cocosci_lab), and Ken Norman (@ptoncompmemlab) for being awarded Princeton Engineering Innovation Grants! Their projects bridge neuroscience, AI, and quantum modeling to understand how the brain learns, perceives, and decides.

Sign up to join a community of Princeton alumni, students, faculty, staff and friends who are committed to making the case for America’s colleges and universities: bit.ly/3YArv7t

It took more than a decade to trace the 130,000 connections in a fruit fly's brain. With the map in hand, researchers are turning to the next step in connectomics: building simulations. By @LauraLauraDat thetransmitter.org/connectome/con…