popo
@PopoMicro
Bacterial transposons; Tn7-like elements; CRISPR; 🇹🇼
Eukaryotes have linear DNA and their telomeres are hotspots for transposons. Many bacteria are also known to have linear genomes. We identified several families of independently evolved telomeric transposons. 1/7 biorxiv.org/content/10.110…
Excited to share our recent findings on Tn7 and its fascinating targeting mechanism, now published in Molecular Cell! 🧬🔬Check it out sciencedirect.com/science/articl…
Happy to share that our last story on Tn7 is finally out. Another example of @shen_yao10 talent and a great collaboration with @JoePetersLab @MikePetassi Assembly of the Tn7 targeting complex by a regulated stepwise process sciencedirect.com/science/articl…
Disclaimer: Photo was digitally edited to include @PopoMicro and @MachadoChacon who couldn't make the photo shot
It was a pleasure working with @PopoMicro on this review of CRISPR-Cas associated transposons (CAST). Hopefully it gives a sense for the diversity of Tn7-like transposons and CRISPR systems that independently combined.go.shr.lc/444PwFh
Hats off to the brilliant minds at Feng lab and Gootenberg lab for their awe-inspiring research achievement! (What a competitive field, people always have manuscripts ready at about the same time) biorxiv.org/content/10.110…
Since the discovery of CRISPR-Cas systems, people have wondered if a similar type of system exists in eukaryotes. Today, we report in @Nature the characterization of Fanzor, a eukaryotic RNA-guided system that can be reprogrammed for human genome editing. nature.com/articles/s4158…
Look what I found! Compliments of the talented @christinerbeck
Happy CSHL transposable meeting! #cshlTE22 @shsternberg @JoePetersLab @ShreyaKrishnan3 @MarcinNowotny @kellogg_liz @Nancy_Craig777 @alba_guarne @PhoebeARice @BarabasGroup @Christinahong9 Dyda lab
CRISPR 2022~ Popo happy~
CRISPR 2022 conference was a blast, with lots of exciting new transposon biology! Fitting, to come just before #TransposonDay2022. We didn’t catch everyone for the pic but some key players @JoePetersLab @kellogg_liz @fthoffmann @MikePetassi …