Pharmacotherapy

The revised scale is recommended as a replacement for the original Anticholinergic Drug Scale (ADS) since it includes ratings for more drugs and was significantly, albeit weakly, associated with cell-based serum anticholinergic activity. OPEN ACCESS: buff.ly/VkBOX3z

Current preferred treatment options in clear cell renal cell carcinoma (RCC), the pharmacology of belzutifan, clinical trial data for belzutifan in RCC, our experience with belzutifan & managing associated anemia & hypoxia, & future uses of belzutifan. buff.ly/SjbOHtv

These results suggest that concomitant PPI use may reduce oxaliplatin discontinuation due to Oxaliplatin-induced peripheral neuropathy in patients receiving oxaliplatin. OPEN ACCESS: buff.ly/6nsv28i

Dr. Aditi Shendre shares her team's analysis of pharmacology knowledge gaps in opioids in the maternal and pediatric populations. Learn valuable lessons for practice from their analysis of this data set. buff.ly/cGrnnjz @OhioStateMed

These two population PK models and all sampling scenarios demonstrated acceptable prediction of cefepime PK parameters and pharmacodynamic exposures; therefore, they demonstrated suitability for utilizing model-informed precision dosing for cefepime TDM. buff.ly/S6qJjAA

Although CrM had no effect on motor function as measured by the Motor Function Measure for Neuromuscular Disease compared with placebo, there were trends toward improvement in the 6-minute walk distance and other secondary outcome measures. OPEN ACCESS: buff.ly/ZXCwLYU

🆕💫 Review article @PharmacoJournal Cefepime-taniborbactam: Ushering in the era of metallo-β-lactamase inhibition #IDXposts accpjournals.onlinelibrary.wiley.com/doi/10.1002/ph…

Congratulations to ACCP member Sean N. Avedissian and co-authors on the recent publication of their article in Pharmacotherapy! Access the abstract and/or article here: ow.ly/HksN50VXjt6 #MakingAnImpact #ACCP @PharmacoJournal

Congratulations to ACCP member Alyssa Christensen and co-authors on the recent publication of their article in Pharmacotherapy! Access the abstract and/or article here: ow.ly/YZNJ50VXjv5 #MakingAnImpact #ACCP @PharmacoJournal

Congratulations to ACCP member Matthew L. Brown on the recent publication of his article in Pharmacotherapy! Access the abstract and/or article here: ow.ly/Kyrx50Wgf97 @PharmacoJournal #MakingAnImpact #OpenAccess #ACCP

The aim of this review was to map the pharmacotherapy research landscape of pharmacokinetic and pharmacoepidemiologic/clinical trials studies on opioids in maternal and pediatric populations. OPEN ACCESS: buff.ly/AkosEGP

Sulbactam-durlobactam monotherapy at 2g Q4h (3-h infusion) in CVVH achieved PD targets for this CRAB isolate with MIC of 4/4 mcg/ml. Monotherapy resulted in initial microbiological clearance but recurrence occurred & the patient ultimately died. buff.ly/jRuysgd

The chloride dipstick rapidly and accurately assessed urine chloride almost 2 h faster than traditional laboratory output in patients undergoing diuresis for acute decompensated heart failure. OPEN ACCESS: buff.ly/pLyTUBQ

The authors evaluate the efficacy and safety of emerging therapeutic strategies for CKD management, including sodium-glucose cotransporter 2 inhibitors, glucagon-like peptide-1 receptor agonists, finerenone, sacubitril/valsartan, and potassium binders. buff.ly/HGKnlw2

Use of mixed-oil lipid injectable emulsion compared to other formulations demonstrated a non-statistically significant increase in 30-day mortality and/or infection persistence in pediatric patients receiving parenteral nutrition. buff.ly/6p7PVrR

This case underscores the feasibility of cautiously escalating stimulant therapy in a breastfeeding mother with ADHD, showing improved functioning in the mother without immediate effects on development in the infant. buff.ly/HxNa7rZ

In older adults with T2D, SGLT2i use was associated with a lower risk of nephrolithiasis compared to DPP4i, particularly among men, non-Hispanic Black individuals, and those without baseline nephrolithiasis. buff.ly/Qmhl2EX

This case supports growing evidence suggesting that rivastigmine may serve as a safe and effective alternative when physostigmine is not accessible. buff.ly/ckG83hf

In this podcast episode, Dr. Michael Rybak hosts authors of the 2025 Update on Antibiotic Safety in Pregnancy. Listen in for a comprehensive review of changes and new drugs that are now available: ow.ly/xv3M50VTkH8 @PharmacoJournal

Congratulations to ACCP member Nicolette Centanni and co-authors on the recent publication of their article in Pharmacotherapy! Access the abstract and/or article here: ow.ly/2B3B50VEWqQ #MakingAnImpact #ACCP @PharmacoJournal