@PennMedBenchmarks

Check out the monthly Benchmarks newsletter, featuring highlights from Penn Medicine’s advancements in preclinical and discovery science. Subscribe to receive new issues as they're released here: pennmedicine.org/news/publicati…

It seems like the nose is key to keeping cold viruses severity in check pnas.org/doi/10.1073/pn… @PNASNews

A pair of new biomarkers could be useful in tracking the effectiveness of therapies for multiple sclerosis, @PennMedicine scientists found @JAMANeuro jamanetwork.com/journals/jaman…

Researchers using the cryo-EM facility @PennMedicine unveiled the inner workings of formins—proteins involved in functions from cytokinesis to mechanotransduction. Formin's atomic structures reveal crucial insights into their functions and role in diseases nature.com/articles/s4158…

Mechanical hyperalgesia is pain from things that should feel like a gentle touch, such as clothes against the skin, but @PennMedicine researchers uncovered clues about what causes this condition to happen nature.com/articles/s4146… @NatureComms

The latest sequencing of centromeres provides even more clues of how interconnected we are without primate cousins, including chimps and orangutans nature.com/articles/s4158…

STINGing CAR Ts, our centromeres and our primate cousins, and how the nose limits how mean viruses can be: Check out our new edition of Benchmarks mailchi.mp/uphs/penn-medi…

An experimental #mRNA vaccine could potentially help manage the outbreak of the avian influenza virus #H5N1 currently circulating in birds and cattle in the U.S., and prevent human infections, according to research led by @SCOTTeHENSLEY and @WeissmanLab. spr.ly/6014e8XAI

ICYMI: @PennMedicine researchers explored why liver inflammation is so critical to cancer's invasions nature.com/articles/s4159…

“I’m still in shock with this discovery. People keep asking me about it, and it’s been a while, but I’m just excited. I’m thrilled.” pennmedicine.org/news/news-blog…

Cancers can manipulate telomeres, which cap DNA, to help their own spread. @PennMedicine scientists just figured out how they do it @MolecularCell cell.com/molecular-cell…

A @PennOrtho team wore gyroscopic sensors around their ankles for this year’s Broad Street Run to collect data on how healthy Achilles tendons work. Dr. Casey Jo Humbyrd and Josh R. Baxter, PhD, outlined their plans for the data. spr.ly/6019jWAgF

Researchers from @PennMedicine and @ChildrensPhila convened for an #autism research symposium. Interim Dean @jonepstein1 celebrated the "quantum advances" in medicine brought about by this collaboration and expressed confidence in future breakthroughs.

A germ-free environment was key to passing along heritable traits that didn't have to do with Darwinian-style gene mutation, a new study shows cell.com/cell-reports/f…

Tatiana Blanchard recently earned her PhD and has begun her career training with the renowned Carl June. She shared her story and detailed work on Ewing's sarcoma biotechtv.com/post/tatiana-b…

Liver inflammation linked to cancer is linked to worse outcomes, but the reason has been unclear. Now, @PennMedicine researchers believe they may have an idea of why nature.com/articles/s4159… @NatImmunol

Non-genetic inheritance, a secret of liver inflammation's role in cancer spread, and a medical school curriculum for climate change. A lot to read in the latest Benchmarks: mailchi.mp/uphs/penn-medi…

Research can often leave out important voices, like people from underrepresented racial and ethnic backgrounds, those who speak languages other than English, or those with limited literacy. A @PennMedicine team is looking to change that. pennmedicine.org/news/news-blog…

Congratulations to @carlhjune, awarded the @brkthroughprize in Life Sciences for the development of #CARTcelltherapy, a revolutionary cancer treatment in which a patient’s own T cells are modified to target and kill their cancer cells.

One study says yes, another says no. So what should clinicians do? Researchers from @PennMedicine received a @PCORI to build a system to help them reconcile situations like these pennmedicine.org/news/news-blog…

Sara Cherry, PhD, and Maayan Levy, PhD, commented on the current state of #longCOVID research and what's needed to better understand the disease, including identifying biomarkers. @PennPathLabMed @PennMicro spr.ly/6011b8t5h