Dominik Paquet
@PaquetLab
#iPSC models and #CRISPR to investigate mechanisms of neuropsychiatric and -vascular disorders, Professor of Neurobiology @ISD_Research @LMU_Muenchen
Open Postdoc position where we still accept applications for a few more days. Please RT and apply!
Open #Postdoc position @isd_research @LMU_Muenchen to develop an #iPSC-derived #BBB model. Fully funded and embedded in our international @FondationLeducq Network of Excellence brenda-leducq.de. Experience in vascular biology or related field required. Please RT and apply!
Open #Postdoc position @isd_research @LMU_Muenchen to develop an #iPSC-derived #BBB model. Fully funded and embedded in our international @FondationLeducq Network of Excellence brenda-leducq.de. Experience in vascular biology or related field required. Please RT and apply!

We @PaquetLab are now also present on Bluesky. Please follow us: bsky.app/profile/paquet…
Congratulations Matthias Tschöp and @LMU_Muenchen !
Herzlichen Glückwunsch, Matthias Tschöp. Der derzeitige CEO des @HelmholtzMunich wurde heute zum neuen Präsidenten der LMU gewählt. Seine sechsjährige Amtszeit beginnt am 1. Oktober 2025. lmu.de/de/newsroom/ne…
Fantastic work, big congrats to the entire @ArthurLiesz lab!
Super exited to share that my postdoc work in @ArthurLiesz lab is finally published in @CellCellPress today!! 🥳 We have identified immune memory after stroke, leading to chronic inflammatory cardiac dysfunction. cell.com/cell/fulltext/…
Big thank you again to our fantastic guest speaker Moritz @mhelmstaedter @mh_lab from @MpiBrain for a really inspiring talk about #connectomics!
ISD teams gathered for annual scientific retreat to present their projects and discuss work. There were presentations from Ph.D. students, a poster session, invited speaker talks, and an amazing three minute thesis competition. @PaquetLab @JekyllSarah @mgeorgakis1
Interested in translational science? 🧪 Our team at #DZNE Munich is seeking a technician for the GA-VAX project. Your work could directly contribute to clinical trials with #C9orf72 #ALS patients. Apply now and join our team! #Jobs #Research jobs.dzne.de/de/jobs/101347…
Don't miss Stephanie Fesser from BioNTech, discussing "Design and Production of mRNA Therapeutics." Join us for a deep dive into the future of medicine! ➡️Lynen Lecture Hall 🕐June 10 at 1:15 pm
Correct link to University news about our recent study: lmu.de/en/newsroom/ne…
#LMU researchers have developed a promising #genetic treatment #method for #frontotemporal #dementia and successfully tested it on mouse models and human neurons in the lab. @LMU_BMC #medicine #treatment #research lmu.de/en/newsroom/ne…
Excited to share a new paper from a close collaboration between @Haass_Lab, Denali and our lab, led by shared grad student @marvinreich93 and Matt Simon. Overview below and full paper here: science.org/doi/10.1126/sc…. Big congrats Matt and Marvin and many thanks to all involved!
Can we achieve protein replacement in the brain using a single dose gene therapy approach, without infecting the brain? Yes we can! Read it here in our latest paper by @marvin_reich in collaboration with Denali Therapeutics science.org/doi/10.1126/sc… (1/8)
📜📸 Some quick snapshots from yesterday's evening at EMBL Barcelona: a poster session and dinner to finish Day 2 of the EMBO Workshop 'Building networks 2024: engineering in vascular biology' #EMBOBuildNetworks
Great to be at #EMBOBuildNetworks and present a talk about our fully #iPSC derived model of the #bloodbrainbarrier! Please contact me in person or via email for further questions. 🙂@EMBLEvents
☀️🤓 The weather outside may be lovely but we've all gathered at EMBL Barcelona to present latest research and listen to excellent talks which our programme is packed full of! #EMBOBuildNetworks A poster session followed by dinner still ahead of us today 📜🍽️
Many thanks Nuria Almiñana @VHIR_ for the talk invitation and great discussions with the research community about the potential of #iPSC models for investigating mechanisms of brain diseases!
At the next #VallHebronTalks by #VHIR, Dr. Dominik Paquet @PaquetLab (@ISD_Research - @LMU_Muenchen) will present 'iPSC- and CRISPR-based 3D brain tissue models recapitulate key features of neurodegenerative and neurovascular diseases'. 🗓️ 2/5 - 3 p.m. ℹ️ vallhebron.social/talk-paquet
For all Array Tomography enthusiasts: Apply now for our AT workshop in Munich, Germany: arraytomography.org/workshop-2024.… #volumeEM #CZI #arraytomography #CLEM #electronmicroscopy
Excited to share this review on one of my favorite biological problems: Selective vulnerability in neurodegenerative disease, and how recent technologies are yielding new insights into the underlying mechanisms. Out in @NatRevNeurosci today! nature.com/articles/s4158…
Big congrats to Carolina Gonçalves from the lab for winning the best poster prize at #StemCellTuebingen meeting 2024!



Cool work, big congrats Tabitha and Angelika!!
Could not be more proud to share the story one of my first PhD students in the lab. Shout out to Tabitha! For more info and links see below.
Imaging Structure & Function in the Nervous System Course @ Cold Spring Harbor. Application deadline 31st March! In-vivo microscopy, optogenetics, behavior, -omics, data analysis… lectures, hands-on labs, builds, projects, guest speakers, TAs, vendors... July 23-Aug 13 2024
Congrats to all organizers for another fantastic #StemCellTuebingen meeting! Great overview of #iPSC based neuroscience in Germany, Europe and beyond! And congrats to all awardees including our own Carolina Gonçalves!
Could not be more proud to share the story one of my first PhD students in the lab. Shout out to Tabitha! For more info and links see below.
Many thanks Zoltan - was really nice to collaborate and have so many fruitful discussion on the #iPSC side of the project!
Did you know Alzheimer's disease might be linked to 3D genome folding? Our new preprint explores the connection! biorxiv.org/content/10.110… #Alzheimer #3Dgenome, #chromatin