Pasquale Paolisso

Our State-of-the-Art Review on Multimodality Imaging in the Diagnostic Work-Up of Patients With Cardiac Masses is now out on @JACCCardioOncology @JACCJournals 👇 sciencedirect.com/science/articl… Role of current multimodality imaging and future directions for their applications: 👥For…

🎯 Meta-analysis to provide the NNT and efficacy of GLP-1RA in reducing risk of myocardial infarction (MI). 👥109,846 pts from 25 studies. Risk-reduction effect of GLP-1RA were pooled using pairwise meta-analysis with a random-effects model. The primary outcome was MI, and…

🫀 Cardiometabolic HFpEF phenotype (cmHFpEF) is rising fast, linked to obesity, hypertension, and chronic inflammation. 🔬 New insights reveal how metabolic stress, immune shifts, and epigenetic changes drive this condition. 🧬 Targeting metabolism, inflammation & chromatin…

Delayed GDMT up-titration in HFrEF? This new study selected by @IzaUchmanowicz in the European Heart Journal combines a standardized 8-week protocol with home-based monitoring to overcome inertia & improve real-world outcomes. 🩺 A practical model for better heart failure care.…

🎯To evaluate the relationship between CMR-imaging and pro-fibrotic/inflammatory serum biomarkers, to discriminate HFpEF from associated comorbid conditions. 👥Prospective cohort study of 35 obese participants (mean age 64 ± 8 yrs, 23% females), including: - 16 with T2DM - 13…

Prevention of #AFib with SGLT2-I across the spectrum of cardiovascular disorders: a meta-analysis of RCTs 📊 🔗 academic.oup.com/ehjcvp/advance… #EHJPharmacotherapy 💊 @EditorEHJCVP 👔 @escardio @ESC_Journals 📚

🚫Therapeutic impasse? Not anymore. Refractory heart failure is becoming a catalyst for change — in strategy, in collaboration, and in outcomes. 🔍 @EmanueleBarba13 & @AlexMebazaa dive into the power of combining pharmacological advances with device-based therapies in a…

🔥Proud to share that #CardiovascularDiabetology has achieved a new Impact Factor of 10.6 - its highest since 2009 - reinforcing its position among the leading journals in the Cardiovascular and Endocrinology & Metabolism fields. 🎯The journal now ranks 14th out of 230 in the…

💊#SGLT2i have emerged as potential cardioprotective agents, reducing cardiovascular mortality and improving #HF outcomes. 🎯Recent evidence suggests that SGLT2i exert anti-inflammatory effects, particularly through modulating the #inflammasome pathway. 🔥This review explores…

🎯To evaluate the impact of #SGLT2i on the risk of acute kidney injury (AKI) in #T2DM pts w/ severe #AS undergoing #TAVI. 👥 Multicenter Registry of consecutive pts stratified by the presence of CKD and anti-diabetic therapy (2021-2024). 🔥Our main findings were: - SGLT2i…

GDMT and LVEF: from static measure to trajectories of change Journal Club review📷 shorturl.at/NVQeQ The clinical paradigm that relies on a static measurement of #LVEF to categorize and manage heart failure is increasingly recognized as reductive. There is a growing need…

🚨We're thrilled to launch Cardiovascular Diabetology’s #KnowTheAuthors project - giving visibility to the brilliant minds behind the science! 🎥 First up: Maria Barranco-Altirriba presents key insights from her study on lipidomics and subclinical carotid atherosclerosis in T2D…

Proud of the amazing Teamwork by the entire Cardiology Team at #AziendaOspedalieraSantAndrea for the two Live Cases broadcast globally during #EuroPCR2025. This is a significant recognition of the teamwork, expertise, and innovation we bring to patient care every day!! 🔥🔥🔥…

🥳Welcome to our New Associate Editors for #CardiovascularDiabetology - @BioMedCentral ⭐️Dr. Idit Goldfracht, PhD Columbia University, New York City, USA Expertise: Tissue engineering, stem cells, cardiovascular disease, 3D printing, biomaterials, vascularized 3D tissues,…

🎥Key insights from the #ImprovingHeartFunction session on refractory #heartfailure at #EuroPCR with Jozef Bartunek and @belmontemarta1

🎤Coming out of the #ImprovingHeartFunction session "Decompensated heart failure: indication and management of mechanical circulatory support" at #EuroPCR, @EGallinoro asked @AlexMebazaa to comment on this very interactive session!

👉Pts with both AS and DM face challenges arising from the interaction between the 2 conditions. 🎯To investigate the effects of DM on the LV remodelling in AS patients, specifically focusing on the inflammatory response and oxidative stress. 👥 LV myocardial biopsies were…

Emerging data suggests that one-size-fits-all troponin thresholds may miss the mark, especially in older adults. Read more in #EHJ. doi.org/10.1093/eurhea… #troponin #ischemic #cardiotwitter @ESC_Journals @escardio