Nima Sharifi
@NimaSharifiMD
Prostate Cancer Medical Oncologist & Scientific Director, Desai Sethi Urology Institute, Sylvester Cancer Center, University of Miami Miller School of Medicine
1/1 I’m excited to share our lab is moving! After 10 years working with incredible colleagues at Cleveland Clinic we are joining @DSUI_Miami_Uro & @SylvesterCancer at @UMiamiHealth! I’ll be Scientific Director of @DSUI_Miami_Uro & we are recruiting! Reach out to me if interested!
Incredibly proud of @Charlie_S_Dai who was previously a fellow in our group and just landed a @DamonRunyon physician scientist grant! Keep an eye on him as he is a next-level thinker and poised to be leading physician-scientist in steroid-dependent cancers! @MGHCancerCenter
Thank you for supporting our work! Hoping it leads to improved understandings in the perturbed epigenome of cancer and new ways to therapeutically target it.
Our last paper in @Annals_Oncology: BRCA and HRR muts have similar prevalence in low and high volume mHSPC, but greater impact in low volume😯. Doublets with ARPi or docetaxel result in comparable poor outcomes for BRCA pts annalsofoncology.org/article/S0923-…
Rana McKay is one of the best there is! Congratulations and well deserved! @DrRanaMcKay @UCSDCancer
We’re proud to present the KidneyCAN Catalyst Award to Dr. Rana McKay of UC San Diego. Dr. McKay is a leader whose work has helped move the field of kidney cancer forward through groundbreaking research, clinical collaboration, and a deep commitment to patients and advocacy. Her…
An Editor's Pick paper at @jbiolchem! Don't forget to read the profile about the first author @li_xiuxiu_ at the end of our paper on HSD3B1 and breast cancer! Dr. Li recently moved from @dsui_miami_uro and @SylvesterCancer to @ONealCancerUAB sciencedirect.com/science/articl…
The 2025 Desai Sethi Urology Institute Pilot Grant Awardees - InventUM @dsui_miami_uro @KatherineAminMD @ZhipengA @AmerUrological news.med.miami.edu/the-2025-desai…
Amazing news ! @brady_urology is so proud of our alumni leaders. @gonzomdphd is among the best there is!! Congratulations
Join us in celebrating @gonzomdphd, M.D., Ph.D., M.B.A., as he steps into his new role as Chair of the Department of Urology @dsui_miami_uro and @umiamimedicine! 🩺 A nationally recognized leader in urologic care, research, and education, Dr. Gonzalgo will oversee and lead…
🧬 New player in ARPI-resistant prostate cancer! HEAL-116, a next-gen 3βHSD1 inhibitor, shows potent tumor suppression, synergy with abiraterone/enzalutamide, and high oral bioavailability. Structure-guided. Clinically promising. #ProstateCancer #DrugDiscovery #Oncology…
Congrats Zhenfei Li and his team on his story @PNASNews on fine structural design of 3βHSD1 inhibitors for prostate cancer therapy! His work builds on many years of work on HSD3B1 genetics and metabolism in prostate cancer! @PCFnews @AACR @ASCO pnas.org/doi/10.1073/pn…
Do you have a primary interest in fundamental mechanisms of human biology, biochemistry, metabolism, genetics, or medicinal and analytical chemistry and looking for a postdoctoral fellowship? @thepostdoctoral @NatureCareers @ASBMB nature.com/naturecareers/…
The kickoff of the @dsui_miami_uro commencement with @dipenjparekh and @gonzomdphd
Excited to share our latest study in JBC! We reveal how SIRT6 adapts to diverse histone acylations through structural and enzymatic plasticity, supported by a new cryo-EM structure of SIRT6 bound to H3K27-modified nucleosomes. jbc.org/article/S0021-…
Congrats @li_xiuxiu_ on her story just out @jbiolchem @ASBMB! HSD3B1 Upregulation via LRH1 Sustains Estrogen Receptor Signaling and Promotes Endocrine Resistance in Breast Cancer - Journal of Biological Chemistry @dsui_miami_uro @SylvesterCancer jbc.org/article/S0021-…
Congratulations @FrancescaBZNY and team! I’m so glad we could contribute to your amazing story at @CD_AACR!
Favorite study! Germline-somatic tandems dictate cancer subtypes, provide clinical insights, and fuel molecularly informed studies. Kudos: Blerta Stringa, @Paola_Gasperini, Alessandro Alaimo, and @LunardiLabCIBIO (co-last a!) @NimaSharifiMD doi.org/10.1158/2159-8… @UniTrento
Favorite study! Germline-somatic tandems dictate cancer subtypes, provide clinical insights, and fuel molecularly informed studies. Kudos: Blerta Stringa, @Paola_Gasperini, Alessandro Alaimo, and @LunardiLabCIBIO (co-last a!) @NimaSharifiMD doi.org/10.1158/2159-8… @UniTrento
Incredible news! Warmest congratulations to @dipenjparekh!!! Looking forward to the next stage of your leadership and even better things to come in the near future! @dsui_miami_uro @AmerUrological
We’re proud to share that the University of Miami Board of Trustees has unanimously endorsed Dr. Dipen J. Parekh (@dipenjparekh) as the next Chief Executive Officer of UHealth and Executive Vice President for Health Affairs at the University of Miami (@univmiami). UHealth and…
Congratulations @Charlie_S_Dai! #ASCO25
🎉 Congratulations to @Charlie_S_Dai @MGHCancerCenter and @maxwellRlloyd @BIDMC_IM on receiving a Young Investigator Award during #ASCO25!
How do #ketones impart their effects? Congrats @ZhipengA on his story elucidating a new mechanism just out in @biorxivpreprint! In his exciting story he shows acetoacetate via #metabolism modifies mitochondrial cysteines! @dsui_miami_uro @SylvesterCancer biorxiv.org/content/10.110…
3rd Annual Maria Becerra Oncology VP @dsui_miami_uro. It was an honor to host Dr Rob Uzzo @FoxChaseCancer @FCUroOnc who shared tremendous knowledge and insight into the evolution of #kidneycancer along with pearls of wisdom on leadership and mentoring
Thrilled to share our @um_svilab work published today in @jclinicalinvest focused on harnessing viral mimicry to activate immunotherapy for #GBM. Thanks to all of my @SylvesterCancer @UMneurosurgery colleagues for their invaluable contributions! jci.org/articles/view/…
Please save the @DeptofDefense Prostate Cancer Research Program! We need continued funding to keep fighting #ProstateCancer @SenAlexPadilla @SenAdamSchiff @RepMikeLevin @urotoday @PCF_Science @soulehoward1 @AndreaMiyahira @Uromigos