Neural Cell News
@NeuralCell
An online resource for the neuroscience research community. Part of the @STEMCELLTech Science News service.
The @MalladiLab reviews the adaptive metabolic reprogramming that facilitates brain metastases and discusses emerging strategies to tailor interventions aimed at preventing and treating overt brain metastases. 📍 Now in @NatureRevCancer: go.nature.com/3TUvAkj

More on mast cells and the brain-dura axis! @DrRishengXu, Dr. Xinzhong Dong, and team show that the mast-cell-specific receptor Mrgprb2 regulates post-stroke brain inflammation from the #meninges. Congratulations! 👏 @CellCellPress | bit.ly/3TYvoR4


Let's hear it for the Kipnis (@jonykipnis) Lab! 🥳 They revealed dural mast cells as central players in modulating CSF flow and meningeal immunity. 🆕 Find their article in @CellCellPress: bit.ly/3H2kE0Y

Have you used @STEMCELLTech products in your #organoid research? Inspire others with your research by sharing your experience with #organoids & get featured on their website: bit.ly/3f9JWfR 🛒 Receive an offer on a future order of organoid media as a thank-you.

Check out this new review from the Deneen lab! 🆕 The authors discuss existing research on astrocyte diversity and examine the developmental origins of these populations and how their interactions with neurons contribute to their functional heterogeneity.…

Discover new biomarkers for #ALS! Dr. Patrick Oeckl and team applied mass-spectrometry-based peptidomic analysis in CSF samples of ALS and non-neurodegenerative control patients for biomarker discovery. 🔎 @EmboMolMed | bit.ly/45egrk2

Dr. @FrigerioIrene and team show that phosphorylated α-synuclein is enriched in putaminal dopaminergic synapses already in early disease stages, and associates with dopaminergic terminal loss. 👉 go.nature.com/3GQ7STm

Dr. @briandanielsli's team used mouse models to investigate RIPK3's role in #astrocytes. Their study, published in @scisignal, suggests that astrocytic RIPK3 promotes host protection during CNS viral infections. 🦠 bit.ly/45com1a

Drs. Linda Partridge and Nazif Alic led this research showing that loss of Pol III repressor Maf1 in neurons promotes longevity by preventing the age-related decline in 5S rRNA and translation. @PLOSBiology | bit.ly/4o0wsla


🖨️ Today in @NatureNeuro! Drs. @TSpiresJones, Claire Durrant, and team conclude that tau pathology could spread at least in part via synapses in progressive supranuclear palsy. 🧠 go.nature.com/4kO82Zl


Are you interested in the Rab3 family proteins (Rab3s)? 😃 Check out this article to know how Rab3s dysregulation disrupts neuronal homeostasis! 🧠 🔄 go.nature.com/3TJ4bSb

📢 New in @NatureComms! This study reveals pathogenic mechanisms underlying early neuropathological features of #AlzheimersDisease and identifies the blood ApoM-S1P complex as a potential diagnostic and therapeutic target. 🔗 go.nature.com/4kzxXE0

⏱️ Final week to enter! Subscribe to one of our 20 immunology or cell biology newsletters before July 18 for a chance to win a personalized lab coat. bit.ly/3YYyzuM

📢 New in @NatureComms! Researchers identify microglial Cx43 hemichannels as a regulator of microglial reactivity in #AlzheimersDisease, positioning them as a promising therapeutic target. 🔗 go.nature.com/406Ygdm

#Myopia is a serious public health issue worldwide. 👁️ Using single-cell #RNASequencing, researchers have revealed anterograde trans-synaptic degeneration and exacerbated synaptic remodeling in myopia. Read the study: go.nature.com/4eJGhj6

Register now for On Demand Access to @KeystoneSymp #Neurodegeneration : Linking #CellularPathways to Therapeutic Strategies, this June to explore emerging research! hubs.la/Q02-rZVb0 #KSNeuroDegen25

Register now for On Demand Access to @KeystoneSymp #NeuroImmune Interactions : A Systems Wide Perspective, this June to explore emerging research! hubs.la/Q02-rZFh0 #KSNeuroImmune25

📢 New in @cddpress! Researchers show that #homocysteine interferes with Ndufa1 leading to mitochondrial dysfunction through repression of the NAD+/Sirt1 pathway in the brain. This suggests a possible link between hyperhomocysteinemia and #neurodegeneration. 🔗…

Interested in the autonomic nervous system? 🤔 A new @NatRevNeurosci #review from the lab of Dr. Yuki Oka at @Caltech discusses the molecular, anatomical, and functional diversity of autonomic motor neurons. 🔗 go.nature.com/3GaYh9q

📖 In their recent @NatureComms study, @LabPascoal showed that #astrocyte reactivity is closely associated with pre- and post-synaptic dysfunction in patients across the aging and #AlzheimersDisease continuum. go.nature.com/40xx9rS
