INEM NECKER

And that’s a wrap! 🎉 The INEM 10-YR Anniversary Symposium was filled with inspiring talks, dynamic Flash Talks by young researchers, and engaging discussions. Thank you to everyone who joined us to celebrate science and collaboration! #INEM10YEARS #INEM2024

[PUBLICATION] The @MEMBRAMICS_lab shows how Influenza A virus rewires ER lipid metabolism to promote viral ribonucleoproteins egress. 🦠 📖 journals.plos.org/plosbiology/ar… Carla Alemany @JulianeDaGraca sharing the first authorship 👏🏼 w/ @institutpasteur & IPNP @PLOSBiology

[PUBLICATION] NEW in @CellReports @JulianeDaGraca et al. show that ER-endosome contacts act as hubs for phagophore formation during starvation. 📖 cell.com/cell-reports/f… @MEMBRAMICS_lab

👏🏼 Proud to see @JulianeDaGraca, former PhD student at INEM, honored with the 2025 Beth Levine Thesis Prize for her outstanding work on autophagy, supervised by Etienne Morel @MEMBRAMICS_lab.

🎉 Congratulations to @JulianeDaGraca, recipient of the 2025 Beth Levine #ThesisPrize! Her outstanding research @MEMBRAMICS_lab on the role of ER/Endosome contact sites in the regulation of #autophagy captures the award's spirit of excellence and innovation. 👏

#France2030 | Félicitations à Guillaume Canaud @CanaudLab, lauréat d’une Chaire d’excellence en Biologie/Santé pour son projet sur les malformations vasculaires liées à KRAS. 🎯Objectif : développer des thérapies ciblées pour une médecine ultra personnalisée. 👏🏼

[CAREER] A 3-year PhD position is open in Paris to explore how air pollution contributes to CKD. The project combines experimental and environmental science and is hosted by INEM & LISA. 📨 Apply by Sept 1. 🟢 Start Nov–Dec 2025. institut-necker-enfants-malades.fr/offre-demploi/…

🚨 We're hiring! INEM is recruiting a Group Leader in #Immunology. Join a vibrant biomedical research institute with strong clinical & academic links. 🗓 Apply by Sept 20, 2025 🔗 More info: institut-necker-enfants-malades.fr/careers

[PUBLICATION] New study with the Bharat lab @CellBiol_MRCLMB reveals the structure of the Neisseria meningitidis filamentous phage MDAΦ. Cryo-EM/ET show how phage bundling supports biofilm formation & pathogenesis. @MathieuCoureuil @PNASNews pnas.org/doi/10.1073/pn…

[PUBLICATION] PIK3CA mutations in Schwann cells trigger neuropathy by disrupting nearby healthy tissues. This non-cell autonomous effect shifts local metabolism toward aerobic glycolysis. Early alpelisib treatment is key | @PNASNews 🔗pnas.org/doi/10.1073/pn… @CanaudLab

🗓️ Join us on July 4, for a #seminar with David Sabatini, group leader at @IOCBPrague. Dr. Sabatini will explore nutrient sensing by the mTOR pathway. Don’t miss it! @MarioPende

[PUBLICATION] mTORC1 governs multiciliated cell differentiation by favoring progression through a cell cycle variant without DNA replication and by acting on cytolinker proteins for centriole disjunction. 📖Read more: embopress.org/doi/full/10.10… @MarioPende

[PUBLICATION] First report of successful pregnancies after treatment with alpelisib for PIK3CA-related overgrowth spectrum. ➡️Fertility preserved ➡️No embryotoxicity ➡️Disease remained responsive after treatment pause 📖Details here: nature.com/articles/s4143…

🗓️ Join us on June 20, for a #seminar with Jean-Emmanuel Sarry @jeansarry, team leader at @crctoncopole. Dr. Sarry will explore Mitohormesis and metabolic adaptations in response to therapeutic stress in acute myeloid leukemia. Don’t miss it!

🚨 We're hiring at INEM! The Immunity in Health and Disease team, led by @FillatreauSimon, is recruiting: 🔬 Assistant Engineer 🧑‍💼 Horizon Europe Project Manager (ARTiDe project) More info & how to apply: 🔗 institut-necker-enfants-malades.fr/offre-demploi/… 🔗 institut-necker-enfants-malades.fr/offre-demploi/… @Inserm

🗓️ Join us on June 13, for a #seminar with Han Li, Principal Investigator and leader of the cellular plasticity in age-related pathologies group at Institut Pasteur. Prof. Li will explore senescence induced-cellular plasticity in health & disease. Don’t miss it! @MarioPende

🗓️ Join us on Friday, June 6, for a #seminar with Elvira Mass, Head of the Department of Developmental Biology of the Immune System at @LIMES_Bonn. Prof. Mass will explore the developmental programming of tissue-resident macrophages. Don’t miss it! @VenteclefNicol1 @ImmediabL

🚨 We're hiring! The @ImmediabL team is looking for: 🧪 1 Postdoc 🧬 1 Research Assistant / Bioinfo/ Tech 📍 Paris | Start Sept 2025 📄 Full details + apply: institut-necker-enfants-malades.fr/careers @DrFAlzaid

[PUBLICATION] Treating patients with somatic PIK3R1 mutations using alpelisib leads to clinical and radiological improvement. A promising step toward targeted therapy in PIK3R1-related disorders. 📄Read more: embopress.org/doi/full/10.10… @CanaudLab @morin_gbrl @EmboMolMed