Ajay Nadig
@NadigAjay
md-phd student @harvardmed @mit in @elisebrobinson and @luke0connor labs/ interested in statistical and functional genomics, developmental neuro, heist movies
Our paper has been published @NatureGenet! Through new statistical methods, we shed light on fundamental questions about cellular response to genetic perturbations. Our work is a substantial advance towards rigorous characterization and comparison of massive perturbation atlases.
How do genetic perturbations change cells? How are these effects shaped by cell type and dosage? How do we best extract insight from modern massive perturbation atlases? Im pleased to share a new preprint where we develop a suite of statistical approaches to these Qs (link below)
New preprint with Guy Sella on the question: what is polygenicity? biorxiv.org/content/10.110…
this take is overstated, but it’s a virtue of a field to respond to critics generously. unfortunately biologists usually respond by ratio’ing the critic.
Peter Thiel said that the lack of progress in biology is partially due to a lack of talent. I think this makes sense. Something about biology's non-technical nature + people's inability to tinker w/biology outside of a lab/PhD make the smartest people select other fields.