Nucleic Acids Chemical Biology Lab, IIT Bombay
@NACB_IITB
Research group of Prof. Pradeepkumar P.I. at @IITBombay. We specialize in the synthesis, biophysical, cellular and molecular dynamics studies of nucleic acids.
Work carried out in collaboration with @SGSrivatsan1 Lab. Probing juxtaposed G-quadruplex and hairpin motifs using a responsive nucleoside probe: a unique scaffold for chemotherapy - now published in Chemical Science pubs.rsc.org/en/content/art…
Sruthi has successfully defended her Ph.D. thesis. Congratulations Dr. Sruthi Sudhakar.
Siddharam has successfully defended his Ph.D. thesis. Congratulations Dr. Siddharam Bagale!
JRF Position in Molecular Modeling Dynamics Studies of Nucleic Acid- Protein Complexes in our group at IIT Bombay bit.ly/4aAlxbf
Annyesha Biswas has successfully defended her Ph.D. thesis. Congratulations Dr. Annyesha!
#SAMURI is a new #ribozyme for RNA-catalyzed labeling of RNA. It uses a new cell-permeable SAM analogue and generates a novel propargylated nucleotide in RNA. Check out the full story doi.org/10.1038/s41557… rclcu.be/dlcxN
New #ribozyme #SAMURI uses a new synthetic cofactor to make #RNA in living cells accessible for #ClickChemistry: Congrats on this publication @NatureChemistry to @HoebartnerLab @JoergLab @Helmholtz_HIRI! ➡️ go.uniwue.de/ribozyme-samuri
Our new work in collaboration with the group of Prof. Kiran Kondabagil at IIT Bombay @KiranKondabagil Human Translesion Synthesis Polymerases polκ and polη Perform Error-Free Replication across N2-dG Methyleugenol and Estragole DNA Adducts pubs.acs.org/doi/10.1021/ac…
Priyanka Deshmukh has successfully defended her Ph.D. thesis. Congratulations Dr. Priyanka!
Our new paper published in @jbiolchem A collaborative effort with Gagnon Lab and @DamhaLab Binding to the conserved and stably folded guide RNA pseudoknot induce... sciencedirect.com/science/articl…
Satendra Kumar has successfully defended his doctoral thesis. Congratulations Dr. Satendra Kumar
Translesion Synthesis across the N2-Ethyl-deoxyguanosine Adduct by Human PrimPol pubs.acs.org/doi/10.1021/ac…
Our work on G-quadruplex have been published in @BiochemistryACS Targeting Parallel Topology of G-Quadruplex Structures by Indole- Fused Quindoline Scaffolds pubs.acs.org/doi/10.1021/ac…
Bisindolylmaleimide Ligands Stabilize c-MYC G-Quadruplex DNA Structure and Downregulate Gene Expression @BiochemistryACS pubs.acs.org/doi/10.1021/ac…
Stabilization and fluorescence light-up of G-quadruplex nucleic acids using indolyl-quinolinium based probes - now published in Physical Chemistry Chemical Physics pubs.rsc.org/en/content/art…
Nucleoside Analogues with a Seven-Membered Sugar Ring: Synthesis and Structural Compatibility in DNA–RNA Hybrids pubs.acs.org/doi/10.1021/ac…
