Mya Tran
@MyaPrecisionG
Precision Genomics Oncology Pharmacist, PharmD, BCOP, Indiana University Health - Simon Comprehensive Cancer Center
50 years.. and countless lives saved! Dr. Einhorn - we’re so grateful for you ♥️ #TesticularCancerCure #ResearchCureCancer @IUCancerCenter




What are "omics"? A good schematic cell.com/neuron/fulltex… could add epigenomics, immunomics, microbiomics, glycomics, exposomics, etc
#PrecisionMed 2025- Dr. Schneider discussed Clinical Utility at IU ASCO25 Review #ASCO25 ✅ Many targets w real activity ➡️ enroll pts on trials! (KRAS, MTAP etc) ✅AI assisted path (TROP2 NMR) ❌ctDNA MRD/dynamics: ?OS ❌MCED: suboptimal LOD for agnostic approach More 2 come!




A friendly, funny, and fierce debate on the timing of IO for resectable NSCLC: ⭐️neoadj @gdurm vs ⭐️periop @RManiarMD vs ⭐️adjuvant @drshieldsmd Never a dull moment at a IU @ASCO Debate! 🏀 @IUCancerCenter #ASCO25 @Pacers @dallasmavs @nyknicks
Fantastic keynote fireside chat with 2024-2025 ASCO President Dr. Robin Zon (@ASCO) & @nabiladra at the @IUCancerCenter #ASCOReview25 on access, knowledge, and support to drive knowledge to action to build a better future for our patients and their families facing cancer.
Fidelity of Next-Generation Sequencing to Predict Human Epidermal Growth Factor 2 Overexpression Across Solid Tumors. Co-authored by @MyaPrecisionG. Read full article. brnw.ch/21wU4vg
Analysis of MARIPOSA @JTOonline comparing 1L lazertinib and osimertinib in #EGFR NSCLC. PFS 18.5m with lazertinib vs 16.6m with osimertinib (HR 0.98), RR 83% vs 85%, DOR 16.6m vs 16.8m, OS HR 1.00 - similar tox (laz more rash, osi more diarrhea). jto.org/article/S1556-…
A first-in-class EGFR-directed KRAS G12V selective inhibitor cell.com/cancer-cell/fu…
The role of whole-genome sequencing for guiding systemic therapy in patients with soft tissue sarcoma in @ESMO_Open. Actionable targets in 46% of STS, specific subgroups with higher prevalence. WGS-informed therapy in 14% of cases. esmoopen.com/article/S2059-…
Why are there intronic reads in your bulk RNA-seq data? You're not alone—it's common, and the reasons are more layered than you think. Let’s break it down. 🧵
WGS strikes again! enable MRD detection at ultra sensitive level, overcoming LoD ~100ppm of WES ➡️ ctDNA clearance during NAC 👉🏻 pCR Many❓remain: tissue requirement? how to account for tumor evolution? role of incorporating other markers? #ctDNA #ASCO2025




Thrilled to share this exciting study @NatureMedicine. Largest integrative analysis of #sotorasib efficacy biomarkers to date. Grateful to all co- investigators and the Amgen team for their hard work and most of all to our patients. @MDAndersonNews #KRAS #NSCLC
Incredibly honored to be a recipient of a @ConquerCancerFd Career Development Award for our biomarker research in #SCLC. Forever grateful to mentors @hannawants2ELCN @christine_lovly & fierce pt advocate @jillfeldman4 for your guidance & support! @IUCancerCenter @SclcSMASHERS
Congratulations to this year’s class of Conquer Cancer grant and award recipients! Are you one of them? Tell us in the comments! We can't wait to celebrate with you at #ASCO25. Full list of recipients: brnw.ch/21wSR0A @ASCO
Good luck Katie!!!! You got this ♥️🔥@ktgminton #smartie 🔬👩⚕️ 🏥
There are no words to express how incredibly PROUD I am of our @TheShieldsLab expert level tech, Katie Minton @ktgminton. Katie has been instrumental 🔑 as a leader in our lab’s 🥼 research on #SCLC from day 1️⃣! We wish Katie ALL THE BEST as she begins her MD PhD @IUMedSchool!
Early data on lazertinib in uncommon #EGFR mutant NSCLC @JTOonline. In 36 pts, RR 50% with mPFS 10.8m, mDOR 15.1m. By mutation, G719X RR 61%, S768I RR 60%, L861Q RR 58%. jto.org/article/S1556-…
Precision oncology in biliary tract cancer: the emerging role of liquid biopsy in @ESMO_Open. Complete review on liquid biopsy in BTC: from different sources and techniques to specific clinical scenarios towards personalized medicine. esmoopen.com/action/showPdf…
Now lets compare Zongertinib with one more Oral TKI in Same space. ( BAY2927088 ) We are in era of Exciting new drugs. Hopefully they will keep their promises in larger data sets also. @OncBrothers @OncoAlert @AACR
New HER2 Targeted Therapy Alert! 🧬 Zongertinib (BI 1810631) = Game-changer? ✅ 71% ORR ✅ 12.4 mo PFS ✅ Active in brain metastases ✅ No ILD ❌ ✅ EGFR-sparing ➔ Less rash, diarrhea! ⚡ Direct comparison vs trastuzumab deruxtecan! ⚡ Clinical MoA snapshot included! Swipe ➡️…
#AACR25 will feature breakthroughs in cancer science & medicine. It's a perfect time to peruse recent work examining 2024 treatment advances in small-cell lung cancer. See @drshieldsmd's video summary below & access the commentary acsjournals.onlinelibrary.wiley.com/doi/10.1002/cn… @OncoAlert @LUNGevity
Congratulations to lung cancer advocate @chrisdraft who will receive the 2025 Marv Levy Impact Award on May 30 at the 2025 @Gridiron_Greats Hall of Fame in Chicago, IL! One of the most positive people I have ever met and deserving of every accolade. gridirongreats.org/halloffame