Alex Morehead (何聪)
@MoreheadAlex
Hopper Postdoctoral Fellow @BerkeleyLab. Prev: #MachineLearning & #CompBio PhD @Mizzou; Research Intern @ Profluent & Absci. #DeepLearning & #GenerativeModels.
I'm excited to announce that GCDM for 3D molecule diffusion generation and optimization is now published in Nature @CommsChem! Paper: nature.com/articles/s4200… Code: github.com/BioinfoMachine…
🔬Interested in training AlphaFold3 faster, at scale, and beyond NVIDIA GPU? Now you can. AlphaFold3 is a major leap in biomolecular modeling, but behind the scenes, it introduces severe system bottlenecks: 🧠 2D EvoAttention spikes memory usage 📉 Retrieval-augmented training…
Delighted to announce that FlowDock has been accepted to ISMB 2025. See you all in Liverpool! Paper: arxiv.org/abs/2412.10966 Code: github.com/BioinfoMachine…
v0.6.0 of PoseBench is now available, featuring (1) results for AlphaFold 3, the new PLIF-WM metric, and (3) the new DockGen-E dataset of challenging docking targets. See the GitHub release below for more details. Paper: arxiv.org/abs/2405.14108 Code: github.com/BioinfoMachine…
Excited to release FlowDock, an all-atom flow matching model for generative protein-ligand docking and affinity prediction (ranked as a top method in CASP16)! Paper: arxiv.org/abs/2412.10966 Code: github.com/BioinfoMachine…
PoseBench v0.5.0 is now released, featuring (1) docking results with AlphaFold 3's predicted protein structures, (2) Chai-1's benchmarking results, and (3) support for running exhaustive HPC benchmarking sweeps. 🧪 Paper: arxiv.org/abs/2405.14108 Code: github.com/BioinfoMachine…
At @icmlconf this week where I'm presenting PoseBench at the AI4Science workshop as a spotlight. I'll also give an oral presentation on RNA-FrameFlow at the SPIGM workshop (AI4Science spotlight as well!) on behalf of many amazing collaborators including @rishabh16_ and @chaitjo.
Introducing PoseBench, the first deep learning (DL) benchmark for practical protein-ligand docking, which provides actionable insights for the development of future docking methods. 🧵 Paper: arxiv.org/abs/2405.14108 Code: github.com/BioinfoMachine…
Unfortunately can't join in-person @icmlconf 🇦🇹 but our awesome co-author @MoreheadAlex will be there!!! Check out our Oral presentation @ SPIGM Workshop on 26 July and Spotlight poster @AI_for_Science Workshop on 27 July ✨🥳 See our poster + schedule below 👀👇🏻
🧬🤖 Introducing RNA-FrameFlow –– an unconditional generative model for 3D RNA backbone design! 📑: arxiv.org/abs/2406.13839 🧰: github.com/rish-16/rna-ba… Our method generates ≥ 40% self-consistent *all-atom* RNA backbones that are globally and locally realistic 💪🏻 1/9
LoG Conference 2024 is back !!!👉 We are looking for more reviewers! We have a special emphasis on review quality via monetary rewards, a more focused conference topic, and low reviewer load (max 3 papers). But for this we need your help! Sign up here: forms.gle/Nuff4ndVZDFTis…!