Sumeet Mirgh MD, DM
@MirghSumeet
Assistant Professor Adult hematolymphoid/BMT, Tata Memorial Hospital, ACTREC, Mumbai. "Crave for excellence in whatever you do"
1/ Our call to action is out in @BloodAdvances! Title speaks for itself. Given concerningly high infection risk with bsAbs in myeloma #MMsm, IVIG/SCIG should be started regardless of any IgG threshold. Global authors & global audience, including insurance & healthcare funders.
One of the issues with "first generation" bispecific TCE in MM is that doses and schedules were developed on the assumption that levels have to be > EC90 all the time. Empirically we are learning that is not the case, less is actually safer and may be better.
That’s what I personally do as SOC, although MASTER-2 and TEC-4 have used 3.0 mg/kg per month at this juncture based on PK data. My humble take - as long as the uninvolved light chains are undetectable, whatever dose frequency you use is working!
Does the dose of Dexamethasone matter in the management of MM? Tune into the @IndMyAcGp Journal club on 22 May at 1730h IST for a better understanding of the long-considered backbone of MM therapy. Also, hear about the MM care in Sri Lanka. @RahulBanerjeeMD @buddhikaprabat3
Outcomes of patients with multiple myeloma undergoing autoSCT with suboptimal pretransplant response. N=1109 with <VGPR to induction. Median PFS/OS: 38.6/103.8 months @BilalAbidMD #mmsm #bmtsm onlinelibrary.wiley.com/doi/10.1111/bj…
Happy to have presented our data on Melphalan dosing and outcomes as oral presentation today at EBMT. Nice to have met seniors and colleagues at Florence #EBMT2025 #EBMT25 @Satyayadav__ @nihardesai89 @Shreyas_H @DrUrmiheme @GJaishetwar @NicoGagelmann @ACTREC_TMC @TheEBMT
Please enroll for the exciting DM/ DrNB quiz for the Hematology and Oncology fellows from the Indian Subcontinent in the upcoming Indian Myeloma Congress 2025. @DrPMPGI @HariMenon68 @reenanair1 @DrNikitaMehra @DrGPrakash @Prasshmehta @PrashantTembha1 @IndMyAcGp
All's well that ends well.. Nice debate on Myeloma MRD today with dear colleague @nikhil91sjmc @Haematocon2024 @DrNikitaMehra @QuantumOnc @vishvdeepkhush @Nehaemat @MkulAggar @drvandanapuri @Jasmita_Dass
Incredible!!! Courage - determination - Focus !!!
Impossible is nothing.
In other news, a woman resident doctor was assaulted by a few drunk men in Sion Hospital. No biggie 🤷🏻 #MedTwitter ndtv.com/india-news/wom…