DNA Methylation
@MethylDetect
Methylation detection kits, controls and services.
🚨Just published in Clinical Epigenetics! 1 in 3 women ≤30 with triple-negative breast cancer (TNBC) carry a hidden BRCA1 epimutation — missed by genetic tests. 🧬 Detected with MethylDetect™ MS-HRM. 👉 doi.org/10.1186/s13148… #BRCA1 #Epigenetics #TNBC #MethylDetect
A new protocol featuring our assays published: High-sensitivity Epimutations Testing with MS-HRM #cancer #BRCA1 #prevention #epigenetics #breastcancer #detection #epimutation #epimelt #prediposition pubmed.ncbi.nlm.nih.gov/39928292/
Constitutional BRCA1 Epimutations: A Key for Understanding Basal‐Like Breast and High‐Grade Serous Ovarian Cancer - Lønning - 2024 - Human Mutation - Wiley Online Library onlinelibrary.wiley.com/doi/10.1155/20…
The evidence for the significance of detectable in blood constitutional #BRCA1 #epimutation in #breastcancer #pathology 📑 🧾 in mounting Our MS-HRM assay can detect this epimutation in single PCR run 🧪 🥼 #epigenetics #cancer #cancerresearch #TNBC genomemedicine.biomedcentral.com/articles/10.11…
This landmark publication confirms that #EPImutation of #BRCA1 #gene is a risk factor for #breastcancer and #ovariancancer, but far more frequent than BRCA1 germline (!) #epigenetics #DNAmethylation #Oncology #mutation.jamanetwork.com/journals/jamao…
Superior performance of our #BRCA1 MS-HRM assay in detection of low level #constitutional #methylation in blood, over #methylation #microarrays for details see publication: #epigenetics #BreastCancer #CancerResearch nature.com/articles/s4159…
We have today updated our website with new products for methylation research, visit: methyldetect.com for details :-) #MSHRM #epigenetics #DNAmethylation #bisulfitemodyfication
We are happy to announce publication of our application note in collaboration with Enzo Life Sciences, Inc. @EnzoLifeSci #epigenetics #biomarkers #epimelt #dnamethylation enzolifesciences.com/about-us/colla…
#brca1 #methylation detectable in blood is a potential breast and ovarian cancer risk factor, see also: #EpiMelthBRCA1 kit methyldetect.com/product/epimel… pubmed.ncbi.nlm.nih.gov/36074460/
Epigenetics and Epigenomics in Health and Disease PMF Brussels 2020 precisionmedicineforum.com/our-conference…
Silencing of the MGMT gene by promoter methylation results in decreased MGMT protein expression and thereby reduced DNA repair activity. This will potentially increase the sensitivity of the tumor cell to chemotherapy.
Epigenetics and Epigenomics in Health and Disease PMF Brussels 2020 precisionmedicineforum.com/our-conference…
Just published a method for automated analysis of #methylation #epigenetics data #PCR #diagnostics Methylation levels assessment with Methylation-Sensitive High-Resolution Melting (MS-HRM) pubmed.ncbi.nlm.nih.gov/36067175/
We can design #methylation #EpiMelt Assay to your region of interest for more info ask [email protected] , #methyldetect #epigenetics #cro #diagnostics #molecularbiology #moleculardiagnostics
Meet our EpiMelt MLH1 methylation testing assay #methylation #epigenetics #diagnostics #cancer #lynchsyndrome #ivd
We have now partnered with bocascientific.com to distribute our products in USA and Canada #methylation #epigenetics #IVD #biomarker #PCR
It was a fantastic meeting with MethylDetect sponsored talk, see you next year at CLEPIC 2023! #methlation , #epigenetics , #IVD , #cancer , #szczecin
Half way through a fantastic meeting - CLEPIC - Szczecin
Our new website is now on-line! check it out 😎😉 methyldetect.com