Mesenchymal Cell News

Scientists including Dr. Franck Dequiedt and Bartimée Galvan reported that independently to its canonical roles in transcription, EWSR1::FLI1 also functions as an mRNA decay factor, reshaping mRNA stability in #EwingSarcoma. 💡 go.nature.com/4lY8Wnz

Taking the tooth as a model organ, scientists employ ssRNA-seq to dissect the cellular composition and heterogeneity of human dental follicle and dental papilla, revealing a distinct #MSC population with remarkable odontogenic potential. 🦷 Give it a read:…

#MesenchymalStemCells have emerged as pivotal tools in biomedical engineering. 🔬 Read about current advancements in #photobiomodulation technology and its application in research below. 👇 bit.ly/4lJNHFT

Findings from this research out of @Tongji_Uni indicate that #MSC-derived apoptotic bodies have the potential to be a promising and effective acellular therapeutic option for treating #MyocardialInfarction. 🔎 Take a closer look: bit.ly/4o3BA85

This study provides insight into the mechanism of action of #BPA and elucidates its impact on the functionality of MSCs isolated from the amniotic membrane of the human term placenta. 💡More in @cddpress: go.nature.com/4o1ocBn

Learn with Dr. Guilin Tang from the MD Anderson Cancer Center (@MDAndersonNews) as she takes you through her lab workflow, from plasma #CellIsolation to FISH assays, when performing cytogenetic analysis of plasma cell neoplasms. @STEMCELLTech bit.ly/4f0w4yR

This media-independent method may open a new avenue for directing MSC differentiation in regenerative medicine. Scientists introduce interfacial silicification, which induces #MSC osteogenic differentiation without the need for BMP-2 and dexamethasone. bit.ly/4kJByze

A team from @Penn investigated the effect of mechanotransduction on human #MSCs attached to structural elements of an implant, specifically a titanium truss element. 🔎 See what they discovered: bit.ly/4lRhmwq

New in @cddpress! 🔎 Jining Medical University researchers suggest that GLUL plays an important role in regulating osteogenic differentiation and bone development, which may have implications for senile #osteoporosis treatment. 🦴 🔓 go.nature.com/4eZMlnW

Researchers applied reversible shearing DNA-based tension probes to assess MSCs’ integrin tension during spreading after biochemical induction to #osteogenesis and chondrogenesis. 👉 More in @acsnano | bit.ly/3GBbRTD

This study validates that the efficacy of #MSCs in the treatment of edematous acute lung injury is associated with keratinocyte growth factor. Learn more from Drs. Hongguang Nie, Yong Cui, and collaborators. 🥼 bit.ly/3It0mhw

Researchers at @EwhaWomansUniv have developed an alternative approach to respiratory #EpithelialRegeneration using human #tonsil-derived MSCs to induce epithelial cell differentiation through a stepwise process. 📑 Read the @JSCTHERAPY study: bit.ly/4kw4k6k

Researchers have introduced a gelated microvesicle–based delivery system to deliver active MSC #mitochondria to injured cells, rescuing mitochondrial dysfunction and thereby treating #MyocardialInfarction. 📝 Read the @PNASNews study: bit.ly/40K4yj6

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related mortality. A #review from the lab of Dr. Asim Duttaroy at @UniOslo focuses on the intricate interactions within the tumor microenvironment and MSCs and their secretome in HCC. 🔗…

The lab of Dr. Verónica Palma at @udechile has developed a safe and effective sponge treatment for #PsoriasisVulgaris, using the secretome from Wharton Jelly-derived mesenchymal stem cells, biologically stabilized and enhanced with hyaluronic acid. Learn more:…

Researchers led by Dr. Bithiah Grace Jaganathan at @IITGuwahati have investigated the cellular effects of PIEZO1, a mechanically activated #IonChannel protein, on proliferation, differentiation, migration, and leukemia support of human bone marrow-derived #MSCs. 📑 Read the…

Just released in @NatureComms! 🤩 Dr. Hongwei Ouyang and co-authors advocate an approach akin to “divide-and-conquer” utilizing engineered OC-like organoids for prompt regeneration of large-sized bone defects. 🦴 go.nature.com/3Ib2ZVf

The authors explore the in vitro biological behaviour of human #MSCs grown on acrylate-based substrates functionalized with biomolecules that play a significant role in the ECM, specifically gelatin and heparin. 🧫 🤩 Give it a read: go.nature.com/44gzhXv

Findings from this recent @NatureComms release reported that #MSC subtypes differentially regulate the development and survival of IL-15-dependent immune cell lineages in the bone marrow. 🔗 go.nature.com/3G9oViW

Stay ahead in stem cell science with Mesenchymal Cell News. 🏃 📥 Subscribe now and get free newsletters delivered straight to you inbox: bit.ly/4kkWMEu