Mashreghi_Lab
@Mashreghi_Lab
http://mashreghilab.bsky.social
Our latest study in @nature reveals how #TGFβ drives Epstein-Barr Virus (#EBV) reactivation in multisystem inflammatory syndrome in #children (#MISC, #PIMS) following #COVID19. @DRFZ_Berlin @Mashreghi_Lab #SARSCoV2 @ChariteBerlin 🔗 Read here: nature.com/articles/s4158…
Big thanks to all my co-authors for their dedication and hard work, especially Roodline Cineus and Yanjiang Luo for their tireless efforts! Special thanks to Nathan West and everyone involved in shaping this story. Truly a team effort!
Excited to share our new study published in @NatImmunol today! We reveal how IL-22 licenses epithelial cells to respond to OSM, driving intestinal inflammation and colitis-associated cancer. #Immunology #IBD #CancerResearch nature.com/articles/s4159…
Top-tier talks on immunology of COVID-19 at the symposium of the European Federation of Immunological Societies (EFIS) ... m.youtube.com/playlist?list=…
D-Lactate drives cytotoxicity in Th1 cells by limiting mitochondrial ROS production through enhanced glyoxalase system activity biorxiv.org/content/10.110… #biorxiv_immuno
New content online: A role for TGFβ and EBV in MIS-C pathogenesis bit.ly/3DUz4yO
Excited to share our latest study by @felix_behrens & J. Holle et al., where we explore how #extracellularvesicles (#EVs) contribute to #cardiovasculardisease disease in children with #chronickidneydisease (#CKD). 📖 Read in JEV: isevjournals.onlinelibrary.wiley.com/doi/full/10.10…
Circulating Extracellular Vesicles as Putative Mediators of Cardiovascular Disease in Paediatric Chronic Kidney Disease - @BiginOsaka Journal of Extracellular Vesicles - Wiley Online Library isevjournals.onlinelibrary.wiley.com/doi/10.1002/je…
Nature research paper: TGFβ links EBV to multisystem inflammatory syndrome in children go.nature.com/3Fmf1cL
Just published @Nature How does #SARSCoV2 lead to the multi-system inflammatory syndrome in children, a rare, potentially fatal condition? High levels of TGFβ interfere with the child's response to control Epstein Barr virus, leading to its reactivation and severe inflammation…
‼️ Cause of post-#COVID inflammatory shock in children identified: Reactivation of the Epstein-Barr virus appears to cause the rare condition #MISC. The findings, uncovered by a team from #CharitéBerlin & @DRFZ_Berlin, have now been published in @Nature. 👉…
‼️ Ursache für Entzündungsschock bei Kindern nach #Corona aufgeklärt: Die als #PIMS bekannte seltene Erkrankung wird offenbar durch eine Reaktivierung des Epstein-Barr-Virus ausgelöst. Das zeigt ein Team von #CharitéBerlin & @DRFZ_Berlin jetzt @Nature. 👉 charite.de/service/presse…