Oxford MND Research

Hello twitter! In light of #GlobalMNDAwarenessDay we have set up a new account to showcase the exciting research from our #MND and #ALS research groups here at the University of Oxford. Give us a follow! 👋👍

New paper out from Jiali and team. Using @uk_biobank data, we quantified how #ALS and #dementia incidence increase with age in carriers of #C9orf72 expansion, and demonstrated that a common #UNC13A variant nearly doubles disease risk. #ALS #MND #FTD. academic.oup.com/brain/article/…

Beatrix from the team is attending #MNDEnCouRage this week, getting to know some of the community and sharing her work #MND #ALS #ECR @mndresearch

Here, Dr Ruxandra Dafinca who is funded by the Foundation through our 2024 Catalyst Award, gives an insight on her research and its potential impact for identifying new therapeutic targets for MND 🔬

Severe weight loss is a major problem for people living with #ALS. New research led by David helps predict who is at highest risk. Check it out below: onlinelibrary.wiley.com/doi/10.1002/ac…

Ahead of #GlobalMNDAwarenessDay tomorrow, we're pleased to announce that The Alan Davidson Foundation has renewed its generous commitment to motor neuron disease (MND) research at Oxford by supporting the ACORN study for a further three years: tinyurl.com/4x5jnb5v @MNDOxford

Great talk by Beatrix from the group on targeted long-read sequencing of the C9orf72 HRE at the ARUK Thames Valley Network Research Day in Oxford today #ALS #FTD

New review led by Lizzie @LizzieDellar from the group on the role of extracellular vesicles in the pathogenesis of TDP-43 proteinopathies and their potential as biomarkers. Check it out below: …arneurodegeneration.biomedcentral.com/articles/10.11…

Thoughts and reflections from Andrew Douglas on the complexity of #ATXN2 in #ALS in a commentary on a recent article about penetrance and pleiotropy in ATXN2-related ALS nature.com/articles/s4143…

Congratulations to Björn @BVahsen for winning the Young Investigator Award at #ENCALS2025 for his work on #microglia in #ALS/#MND!🌟

Congratulations to Michael for winning a rapid fire presentation award at #ENCALS2025 last week for his talk on "Divergence of cortical neurophysiology in ALS and other neurodegenerative disorders from healthy ageing". 🌟

Final day at #ENCALS2025: watch out for Björn's @BVahsen talk this afternoon!

Also watch out for Michael’s rapid fire talk in the morning session!

Looking forward to day 2 of #ENCALS2025. Check below for posters from our team this evening!

Join the Hallegger Lab in Oxford. A post-doc position available to develop neuronal cell models to characterise how TDP-43 aggregation leads to its dysfunction in MND. Highly collaborative project funded by My Name'5 Doddie Foundation @MNDoddie5 Please repost and share widely!

And one more poster at #ENCALS2025 - make sure to check out Alicia's poster later today!

We are excited to be here in Turin for #ENCALS2025! Come and check out our posters later today - see below for our presenters and poster numbers #MND #ALS

Excellent talk by Lizzie @LizzieDellar on UCHL1 in asymptomatic C9orf72 HRE carriers at the FTD UK meeting in Edinburgh last week #ALS #FTD

New analysis on #PLS led by David. Diagnosis of #PLS shown to be compatible with near-normal life expectancy. Research to find better treatments is increasing globally. jnnp.bmj.com/content/early/…

🚨Come and join us! Postdoc position here at @MNDOxford @NDCNOxford, working on local subcellular dysfunction in synapses of neurons from #ALS/#FTD patients using multi-omics with @RDafinca. Check out the details below: jobs.ac.uk/job/DMV265/pos…

New review from Katie and the team assessing the clinical, neuroimaging and histological evidence for asymmetry in #ALS. Check it out below: academic.oup.com/brain/advance-…