Matteo Castrichini, MD
@MCastrichiniMD
FACC🇺🇸, FESC🇪🇺| Cardiology Fellow @MayoCVFellows @MayoCITProgram @MayoMN_IMRES | PhD student @MayoGradSchool | MD @unipr 🇮🇹 |🧬🫀⚡️
Excited to share our new multicenter study published in @JACCJournals highlighting the need for deep phenotyping (#WhyCMR) in dilated and arrhythmogenic cardiomyopathies. @MayoCVFellows @MayoClinicCV @MJAckermanMDPhD @JohnGiudicessi @nl_pereira authors.elsevier.com/a/1j2Rl2d9GH%7…

Cardiology Fellowship applicants- I am looking for a new clinical research fellow for sports cardio to start July 2026! 2 yrs research, then gen cards! Apply to @EmoryMedicine Cardiology if interested! @austinjrim @JasonTsoMD #sportscards
Big thanks to @JohnGiudicessi for the outstanding mentorship! LMNA IgD variants (p.Arg471, p.Arg541) = distinct apical variant w transmural LGE + elevated arrhythmic/stroke risk. Genotype–phenotype drives precision! 🔗 ahajournals.org/doi/epub/10.11… #CardioTwitter #LMNA #ACM
Not all LMNA missense variants are lower risk. Variants involving p.Arg471 and p.Arg541 in the IgD domain result in a distinct LGE pattern and increased risk of VA/stroke. Big shootout to @MayoClinicCV CI fellow @MCastrichiniMD! ahajournals.org/doi/epub/10.11…
New online! Gene therapy for cardiac arrhythmias nature.com/articles/s4156…
This paper shows what we always suspected: any cut offs values for endocardial voltages for diagnosing scar correlate poorly with histology, at least in non ischemic CMP. The same is likely true for atrium too?
Very important study. This is a paradigm shift. #openaccess MYL4 Identifies Intramural Anatomy of Purkinje Fibers in Human Hearts | JACC: Clinical Electrophysiology jacc.org/doi/abs/10.101…
🔴Restrictive cardiomyopathy: definition and diagnosis⤵️State of the Art #Review #OpenAccess 🔹academic.oup.com/eurheartj/arti… #Cardiology #FOAMed #MedEd #medstudent #paramedic #Cardiology #CardioEd #medtwitter #meded #CardioTwitter #cardiotwiteros #MedX #cardiovascular #MedTwitter
Cardiac conduction system involvement in STEMI Now we know why AV blocks in inferior STEMI are more common than SA blocks.
3 generations of @MayoMN_IMRES residents re-uniting @HRSonline #HRS2025 🫀⚡️ @iShadrinMDPhD @MCastrichiniMD #OmarLatif @CaThompsonMD @MayoClinicCV @DukeCardFellows @OhioState
Sicklinger & colleagues developed a new #ultrasound-guided method to induce #HeartAttacks in mice, allowing precise control & real-time monitoring without the need for invasive surgery. Learn more at ahajrnls.org/42R7ZGs @volkersmirko @junedh_amrute @rkramann
AHA/ACC Class I 2025 ACS Recommendations In one slide: Always remember what to do!
Dear colleagues and friends, We are pleased to share with you our recent work. @JACCJournals #JACCEP “Left Bundle Branch Pacing: Histology, the Key to Understand Different Responses” kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2… “A picture is worth a thousand words.”👇
Great session! Thanks @VizentinVanessa for the picture and thanks @JohnGiudicessi @MJAckermanMDPhD for the great mentorship! #HRS2025 @MayoEPFellows @MayoCVFellows @MayoClinicCV
Great presentation by my lab colleague @MCastrichiniMD on stress test in PKP2 arrhythmogenic cardiomyopathy at second day of #HRS2025
Cardiac Electrophysiology Society 2025: Frequent peripartum ventricular ectopy—a potential sex-specific feature of CDH2-related arrhythmogenic cardiomyopathy. Grateful for Dr. Giudicessi’s mentorship! #HRS2025 #geneticACM @JohnGiudicessi @MCastrichiniMD @MayoCVFellows
📣 📣 Don’t miss our oral presentation at #HeartRhythm2025 in San Diego! “Prognostic Significance of Exercise Stress Testing in Desmosomal ACM” April 25 | Hub 5 | Sails Pavilion @JohnGiudicessi @MJAckermanMDPhD @MayoEPFellows @MayoCVFellows #EPeeps #HRS2025 Let’s talk rhythm!🫀🎶

Great time at #ACC25 sharing exciting new findings in the fascinating world of genetic cardiomyopathies. Grateful for the chance to connect, learn, and contribute to the future of heart care. @ACCinTouch @MayoClinicCV




Not all apical hypertrophy is the same. We know this from practice. Nice to have data reflecting on this. ahajournals.org/doi/full/10.11… #CardioTwitter
It s an honor to be part of it! ECAS Concise Guidelines on Atrial Fibrillation Catheter Ablation doi.org/10.1111/jce.16… #Afib #WomeninEp #ECAS #ablation