Shixian Lin
@Linlab_ZJU
Chemical Biologist and Synthetic Biologist; Associate Professor at Life Sciences Institute Zhejiang University
Thank you🥰. Having the opportunity to publish in @ACSCentSci is a wonderful and very memorable experience.
The Lin lab (@Linlab_ZJU) developed a virtual noncanonical amino acid (ncAA) screener that allows evaluation of the genetic encodability of designed ncAAs prior to chemical synthesis. NEW #ASAP #ZhejiangUniversity Read: go.acs.org/c8T
Check out our work in @ACSCentSci. We have developed a virtual noncanonical amino acid (ncAA) screener that allows evaluation of the genetic encodability of designed ncAAs prior to chemical synthesis. pubs.acs.org/doi/10.1021/ac…
It's great to see this review online @ACSChemRev. Many thanks to the collaborators, reviewers, and organizers of this synthetic biology review @syntheticbiology. We hope that this review will be useful for researchers interested in protein lipidation. pubs.acs.org/doi/10.1021/ac…
Thank you for covering our study.🥰 @TheScientistLLC @KLNahas
The 20 amino acids that make up proteins produce an incalculable variety of these biomolecules, but synthetic biologists looking to push the limits of protein diversity have developed a technique to incorporate unusual amino acids into proteins. bit.ly/46BnfqW
Terrific idea that can activate different reactive probes with tunable radical half-lives corresponding to different distance scales.
Thrilled to share our MultiMap paper is now published online on Science. @ScienceMagazine With @realJimWells, we present a multiscale photocatalytic proximity labeling platform for interactome profiling. science.org/doi/10.1126/sc…
Well Deserved! Huge Congratulations!
Congratulations to Prof. Ashraf Birk for winning the “European Peptide Society's LEONIDAS ZERVAS AWARD 2024”! @AshrafBrik
Genetically encoding negatively charged lysine PTMs succinylation/glutarylation and studying their funcional roles! Great team effort by first authors @ML_Jokisch and @Maria_Weyh! Congrats @Maria_Weyh @ML_Jokisch @MaxFottner and Anh! 🥳🤩🙌👨🔬🧑🔬 @klanglab nature.com/articles/s4155…
Phenomenal new reactions, new oxaziridine reagents, and their application in the discovery of functional tryptophan interactions. 👍👍👏👏 @christhechang @Toste_Group nature.com/articles/s4158…
This chemical activation of a genetically encoded caged-tryptophan (Trp-CAGE) strategy enables precise activation of the Trp of interest underlying diverse important molecular interactions, such as hydrophobic interactions, polar interactions, and π interactions. @NatureChemistry
Thrilled to share our collaboration work with Peng and @fanxy03 on @NatureChemistry. With a new bioorthogonal reaction, the chimeric translation system, and a new computer algorithm, we can cage and decage Trp on virtually any protein in living cells. nature.com/articles/s4155…
Happy to share that I have been promoted to Associate Professor with tenure. My sincere thanks to all the amazing colleagues, trainees, mentors, and friends over the years.❤️
We got a story, and it’s electric! 🔌⚡️ rdcu.be/dth70 Can electrocatalysis be used to precisely modify a protein? Yes! Happy to finally share this work led by @conor_loynd and @SinghaSoumya. A 🧵 #ProteinElectrochemistry #NSFfunded
🎁Interested in reading more about the study? Here is the N&Vs article written by Jennifer J. Kohler and Mary W. N. Burns: 👉🏻rdcu.be/drQk0 nature.com/articles/s4155…
Our first study of the biological function of protein #OGlcNAcylation #PhaseSeparation, with more interesting findings coming soon. 🤞🤞
💫NEW: Chen et al. report that the #YTHDF #m6A-RNA-binding protein family can be differentially regulated by #OGlcNAcylation, leading to differential regulation of the YTHDF proteins on translation and #PhaseSeparation. 👉🏿rdcu.be/drQi8 nature.com/articles/s4155…
It is our great pleasure to announce that Christopher Chang @ChristheChang has joined @PrincetonChem as the Edward and Virginia Taylor Professor of Bioorganic Chemistry. Welcome, Chris, we are thrilled to have you! Read here: bit.ly/49JJsV4
It is our great pleasure to announce that Michelle Chang has joined @PrincetonChem as the A. Barton Hepburn Professor of Chemistry. Welcome, Michelle, we are thrilled to have you. Read here: bit.ly/3R69meh
Congrats to Chris Chang on being name the next ACS Editor-In-Chief of Accounts of Chemical Research! axial.acs.org/cross-discipli… @christhechang @AmerChemSociety