Lingjun Li Research Group
@LiResearch
Student-run account for the @LingjunLi2 Research Group @UWMadisonChem and @UWMadPharmacy. #TeamMassSpec
Exciting paper in @naturemethods that pushes the boundaries of MSI and spatially-resolved omics🥳TEMI reaches single-cell spatial resolution and enables the profiling of hundreds of lipids, metabolites, peptides, and N-glycans in complex tissue. Check out: rdcu.be/eiIWy

Wrapping up #ASMS2025 strong! @tito_chemistry will be presenting an oral on sialic acid isomer characterization using permethylation & ion mobility-MS/MS 🥳 Don't forget to check out our 3 last posters on crustacean metabolomics and proteomics, and carboxylate enantiomer analysis

Join us on the first day at #ASMS2025! Dr. Wei (Wilson) Li will be presenting an exciting oral on a novel chemoproteomic platform for reliable citrullination mapping in Alzheimer’s disease 🤓 Plus, don’t miss out 5 posters covering proteomics, MS Imaging, and ion mobility 🎉

Li Lab spent a fun summer Sunday night with a cozy fire pit hangout at Picnic Point🔥 Delicious s’mores, sausages, snacks and furry friends🌽🍫🧀 🐶The highlight? A surprise birthday celebration for our amazing PI🎂🎉 Thank you for always supporting us in everything we do💜




Check out this interview by @UWMadPharmacy, featuring our recent work on TEMI, where we're pushing the boundaries of MSI and spatially resolved omics 🥳🥳 Congrats to @Huazhang88 and coauthors! Read here: news.wisc.edu/uw-madison-sci…
Excited to share our latest review on @molcellprot, highlighting recent and emerging MS advancements for investigating post-translational modifications in Alzheimer’s disease 🥳🥳 Congrats to @Feixuan_Wu, Wilson, and @Happysmilexyz68 🎉🎉 Link: doi.org/10.1016/j.mcpr…

Huge congratulations to Li Lab Ph.D.s #70 and #71 — Dr. Wenxin Wu and Dr. Zicong Wang 🥳🥳🥳 Your dedication, brilliance, and mentorship have left an unforgettable mark on the lab. Wishing you both all the best in your next chapters 🌟🥂🍰🍕




Check out our latest review, featuring recent advances in chemical labeling strategies, including activity-based protein profiling (ABPP), proximity labeling (PL), and proteolysis-targeting chimeras (PROTACs) 🥳🥳🥳 Congrats @PK_Liu_ and Zicong 🎉🎉 Link: doi.org/10.1016/j.cbpa…

Congrats to @Feixuan_Wu and co-authors for having their work featured on the cover of @molcellprot May 2025 Issue 🥳🥳 Special thanks to @UWMadPharmacy Sally Griffith-Oh for drawing this beautiful cover 🎨🎨 Check out the paper: doi.org/10.1016/j.mcpr…
Researchers developed a global quantification strategy enabling fractionation of hydroxyproline peptides labeled w/12-plex DiLeu isobaric tags & applied this pipeline to investigating proline hydroxylation alterations in various types of PDAC. mcponline.org/article/S1535-… #asbmbMCP
Congratulations to all of the @uwmadison faculty honored with @WARF_News named professorships, Romnes Fellowships, and Kellett Awards — including School of Pharmacy Professor Lingjun Li (@LiResearch), honored with a Kellett Mid-Career Award! research.wisc.edu/faculty-receiv…
Check out our latest review on @rsc_chembio, featuring quantitative MS-based strategies for neuropeptide analysis and highlights their applications on revealing neuropeptide roles in biological systems 🤓 Congrats to @tito_chemistry, Wenxin and Haoran 🥳 pubs.rsc.org/en/content/art…
Why is cocaine so addictive? A new study from Professor Lingjun Li (@LiResearch) reveals that it’s not just about dopamine — neuropeptides across the brain play a key role. These insights could lead to better addiction treatments. Learn how: pharmacy.wisc.edu/2025/03/22/unl…
Warmest congratulations to Dr. Hannah Miles @HNMiles, the 69th Ph.D. from the Li Lab 🥳🥳🥳Your support for fellow lab members, triathlon training inspiration, and fruitful collabs with @LabRicke have truly left a lasting impact. Wishing you the best on your next adventure 🍾🍰




Li Lab had a great time at #ASMS2025 in Baltimore, MD ☀️🌊🐟🦀🦞 22 posters, 4 orals, 2 awards, and a plenary talk by our PI @LingjunLi2 🤓 A fun Li Lab Reunion Dinner, closing event at the National Aquarium, and IonOpticks cruise trip with great views, drink, and DJ set 🛥️⚓️




#ASMS2025 was a wonderful #TeamMassSpec experience. Our session chaired by @LiResearch was awesome with great talks. Having the shuttle buses arranged was an incredibly thoughtful touch. My personal version of Faces of MS this year:
A busy Day 3 at #ASMS2025 for the Li lab! We’ve got 10 posters covering a wide range of exciting topics. Stop by, check them out, and feel free to ask us any questions 🤓🤓

Good morning #ASMS2025! Today @Shuling_Xu_ presents on characterizing ganglioside isomers via high-res ion mobility-MS/MS, and @Feixuan_Wu on high-throughput quantification of O-glycosylation in diabetes 🥳 Plus, 4 posters in multiomics, DIA, TEMI, and glycopeptide enrichment 🤓

Happy Li Lab Dinner Reunion😍#ASMS2025 allows us to have a delicious meal at a local restaurant. We're all fueled to learn and share cool science over the next few days. Also, kudos to our PI @LingjunLi2 for delivering a fantastic talk at the @bsi_peaks User Meeting 🥳




#ASMS2025 🥳 We're ready 🔥🔥🔥 Madison ✈️✈️✈️ Baltimore, MD!

A warmhearted congrats to Li Lab 67th and 68th PhDs, Dr. Malik Ebbini and Dr. Olga Riusech 🥳🥳🥳 Your kindness and smile will be missed! Best wishes to your future endeavors 🍾🍾🍰🍰




#ASMS2025 is around the corner and we can't wait to share our latest MS research with you 🥳🥳🥳 Check out the special presentation of our PI @LingjunLi2 at the @bsi_peaks User Meeting, 4 exciting orals and 22 informative posters from our lab this year 🤓🤓🤓



