Leon Hilgers
@LeonHilgers
Moved: @leonhilgers.bsky.social Postdoc @LOEWE_TBG @Senckenberg. Comparative genomics, gene expression, novelty, global change, climate, turtles & eels! He/him
‼️These #PSMC #peaks are #artifacts‼️ Seen #PSMC results like this🤔? They are caused by ill-set parameters, #very #common, and #easy #to #solve! For details see 🧵& biorxiv.org/content/10.110… Thank you @kguschan @hillermich @RegevSchweiger @trevorcousins_ @axel_jensen ! 🙂

You link #phenotype 🦜 to #genotype 🧬 using #comparative #genomics 💻? This #review is for you 📜: authors.elsevier.com/sd/article/S... We review new #methods, remaining #challenges and #future directions and highlight recent key studies. Thanks @hillermich ! Please share! 🙂

How to remove false peaks from your PSMC/MSMC2...now out in @CurrentBiology 🙂🐢🧬🎉! See the OA paper or thread below🧵 cell.com/current-biolog… Thanks to a fantastic team: Shenglin Liu @hillermich @kguschan Tom Brown @axel_jensen @RegevSchweiger and @trevorcousins_ 🙂 !!!
‼️These #PSMC #peaks are #artifacts‼️ Seen #PSMC results like this🤔? They are caused by ill-set parameters, #very #common, and #easy #to #solve! For details see 🧵& biorxiv.org/content/10.110… Thank you @kguschan @hillermich @RegevSchweiger @trevorcousins_ @axel_jensen ! 🙂
Join us at the Gordon Research Seminar on Ecological and Evolutionary Genomics in Tuscany, co-chaired by Joaquin C. B. Nunez and me. If you’d like to present your research and be considered for a talk, make sure to submit your application before April 6th! grc.org/ecological-and…
Bats 🦇really are special, and so is their immune system🦠🧬!! Very happy to see this work on #bat 🦇immune system adaptations out in @Nature 🙂! Congratulations to everyone involved, especially @_AriadnaMorales & @hillermich 🎉!
Happy to report that our work on immune system adaptations in #bats is now out in @Nature 🦇🧬nature.com/articles/s4158… @_AriadnaMorales @BatResearch @sci_questions @bat1kgenomes @Senckenberg @LOEWE_TBG Read more ...
Thanks so much to everyone @popgroup for one of the best conference experiences I have ever had #Popgroup58 🎉🎊. People, research and general vibe were all just fantastic🙂! See you soon and avoid the turtle peak😉!

Check out Dimitrios Kontopoulos @DGKontopoulos paper on the evolution of torpor & associated traits. We find a low prob for hibernation in ancestral mammal. besjournals.onlinelibrary.wiley.com/doi/full/10.11… DGKontopoulos.ecoevo.social.ap.brid.gy @LOEWE_TBG @Senckenberg @EMBO
Please RT: we have @snsf_ch -funded #Postdoc and #PhD positions in our lab, to investigate the gene regulatory dynamics during vertebrate skeletogenesis in a comparative setting (see doi.org/10.1101/2024.0… and doi.org/10.1101/2024.1… ) - apply by 31.12.24, start date by 1.2.25!
Snails 🐚 are slow, but they can evolve fast! Our new paper shows how one ecotype evolved into another on a tiny island 🏝️ within 30 years - and that we could predict changes at the phenotypic, but also at the genetic 🧬 level. 1/3 #Evolution #Genomics science.org/doi/10.1126/sc…
Call for Papers! Special Issue: Functional and Adaptive Effects of Genomic Structural Variation in Heredity 📅 Submission Deadline: 1st March 2025 Guest Editors: @ellenleffler, @meganydennis, Omer Gokcumen, and myself Please check the link for details: nature.com/collections/de…
📢 A fully funded 4y PhD contract at the @mncn @DPE_CSIC Madrid under my supervision, starting in early 2025. DM/Email if interested. Pls retweet 🙏
Muchas gracias a todos @ #SMBE2024 @OfficialSMBE! It was absolutely fantastic and I hope to be back soon! 🙂🇲🇽

I am very happy to be at #SMBE2024 to receive the amazing news that we are bringing #SMBE2026 to Copenhagen!! Thanks for the vote of trust @OfficialSMBE
📣📣📣 Velkommen to #SMBE2026 in Copenhagen, Denmark. Congratulations to the Copenhagen Team on a very convincing presentation and the successful bid.
Important findings on artifacts in PSMC curves arising from time segmentation/windowing choices, and advice on how to avoid these.
Avoidable false PSMC population size peaks occur across numerous studies biorxiv.org/cgi/content/sh… #biorxiv_evobio