LechtenbergLab
@LechtenbergLab
News and updates from the Lechtenberg Lab at WEHI in Melbourne. Interested in Ubiquitin ligases, protein structures, and drug discovery. Views my own.
Excited to share our latest preprint on @biorxivpreprint: "The RBR E3 ubiquitin ligase HOIL-1 can ubiquitinate diverse non-protein substrates in vitro". biorxiv.org/content/10.110…
World-first: researchers have discovered what protein #PINK1 looks like in humans and how it is activated, solving a decades-long mystery in the fight against #Parkinsonsdisease. The team hope to use the knowledge to find a drug to stop #Parkinsons. wehi.edu.au/news/scientist…
Online Now: Combinatorial mapping of E3 ubiquitin ligases to their target substrates dlvr.it/THqW1q
📣📣 Lorne Ubiquitin – The Australian Ubiquitin Summit 📣📣 20-23 Nov 2025 in Lorne, Australia Join us this Nov for the first ubiquitin meeting in Australia. Submit your abstract by 18 July 2025 for oral and poster presentations: lorneubiquitin.org Please share and repost.

Australia’s First Ubiquitin Summit is here! 🥳 📍Lorne, Victoria | 🗓️ 20–23 November 2025 Join us on the scenic coastline of Lorne for 4 days of cutting-edge ubiquitin science, featuring a fantastic lineup of international speakers covering all corners of the ubiquitin world
Join us in Lorne for the 11th ISA. We have a fantastic line up of speakers at a beautiful coastal location in Australia. Hope to see you there!
Michael Lazarou and I will be chairing the 11th International Symposium on Autophagy (ISA) in Australia from 16-20 Nov 2025! 📍 Location: Lorne, Victoria, Australia 🌐 Register now: isa11.org Join us for five inspiring days of cutting-edge autophagy research!
Super excited to be joining @RACInational for #MCCB2025 in Darwin #NT this April!! #chembiol #drugdiscovery #peptides #ozchem
Join keynote speakers Dr Pat Sharp, Dr Chiara Maniaci, Prof. Xin Zhang & Dr Madeline Kavanagh in Darwin (13-16 April) for insights into medicinal chemistry & chemical biology. 🔗 bit.ly/3PNkUl6 #MCCB2025 #MedChem #ChemBio #DrugDiscovery #NT
For those wanting to try to ubiquitinating sugars themselves: our plasmid for bacterial expression of the constitutive HOIL-1 variant is now available via Addgene: addgene.org/229539/
Excited to share our latest preprint on @biorxivpreprint: "The RBR E3 ubiquitin ligase HOIL-1 can ubiquitinate diverse non-protein substrates in vitro". biorxiv.org/content/10.110…
I am looking for a research assistant to join my new lab in Melbourne, Australia at WEHI. Please apply at the link below! tinyurl.com/4wkt2jve
Just announced by WEHI, Sir Gus and the Nossal family: the Sir Gustav Nossal Professor of Immunology. This prestigious new position will lead pivotal research to advance human immunology. Made possible by a generous gift from the Nossal family. Read more: wehi.edu.au/news/sir-gusta…
Sarah is rocking the stage at #EMBOubiquitin24 presenting her PhD work.

Interested in Honours, Masters, or PhD studies in medical research? We have over 70 student research projects starting in 2025, across the breadth of research areas at WEHI. Explore the opportunities here: wehi.edu.au/education/stud… #WEHIStudents #StudyInMelbourne #UniMelb
Discover your opportunities for biomedical research training at WEHI’s Student Open Day – 5 September. 🔹Honours, Masters and PhD application and scholarship info 🔹Discuss research projects with supervisors 🔹Meet our students Learn more 👉wehi.edu.au/education/stud…