Keith Ligon
@KeithLigon5
pathologist - scientist - director of center for patient derived models @CancerModels - co-founder Travera
Great review from friends and former @BWHNeuropath @BWHPath colleagues Rebecca Folkerth and Barbara Sampson on Forensic Pathology | New England Journal of Medicine nejm.org/doi/full/10.10…

Heterogeneity only now coming in view through large scale efforts - this clearly demonstrates how in #gbm and other heterogeneous cancers if we don’t study 100+ patients then we are not going to solve the problem. Thx to all for opp to contribute to this effort.
1/ Thrilled to share our TWO back-to-back papers published in Nature Genetics today! nature.com/articles/s4158… , nature.com/articles/s4158…
Check out poster Today 9am at #AACR25 by amazing postdoc and future pathologist Georges Ayoub and friends on pathologist-oriented AI automated and quantitative digital pathology approaches defining pathological response in #gbm @DanaFarberNews @break_cancer @MGBpathology

Check out #AACR25 presentation of the @theNCI Human Cancer Models Initiative update by postdoc @DElharouni at 3pm today! 600+ organoid and NextGen patient models of cancer. Great collaboration with whole HCMI team @DFCI @broadinstitute LigonLab and Cancer Cell Line Factory…

Great story from Burns lab highlighting some of the exciting things happening in @DanaFarber Pathology
Happening Monday at #AACR25: @DanaFarber's @KathleenHBurns is an invited speaker in an early detection and interception session exploring cutting-edge blood-based cancer detection technologies. ➡️ bit.ly/3YgMNad
We’re on our way to #AACR25! Whether you'll be in Chicago April 25-30 or attending virtually, follow @DanaFarberNews for important research findings by @DanaFarber faculty across a spectrum of cancers. Complete list of DFCI oral abstracts: bit.ly/42Q5F1a
Breaking News: Court Throws Out LDT Rule. “The FDA’s LDT rulemaking was burdensome, and the court rightly struck it down,” said CAP President @DonKarcherMD. “The CAP and its members are relieved that the court agreed with our arguments.” brnw.ch/21wRHqD
Great opportunity to help develop and translate @DanaFarber diagnostics for patients. careers.dana-farber.org/job/11134/busi…
Explainable artificial intelligence of DNA methylation-based brain tumor diagnostics - Nice work from friends in the @hovestadt lab and in Heidelberg on deeper understanding of drivers of classification nature.com/articles/s4146…
CAP urges HHS to revoke lab developed test rule, citing Trump order medtechdive.com/news/cap-hhs-l… via @MedTechDive
Check out our latest work on MDM2 as a validated target in #gbm. Super collaboration with @veronica_rendo Kalem Lee @SantagataMDPhD @RameenBeroukhim Patrick Wen and team @KartosThera and the patients who contributed science.org/doi/10.1126/sc…
CAR T cells, CAR NK cells, and CAR macrophages exhibit distinct traits in glioma models but are similarly enhanced when combined with cytokines: Cell Reports Medicine cell.com/cell-reports-m…
Congrats David! Wonderful to see your groundbreaking work @MGBpathology @BWHPath @DanaFarber receiving accolades and having you as a colleague. #PrecisionMedicine
Congratulations to David Walt, PhD, a Brigham pathologist, on receiving the National Medal of Technology and Innovation from President Joe Biden (@POTUS) today. This award is the nation’s highest honor for technological achievement. Learn more: spklr.io/6014LNgq
Congrats Azra!
The American Board of Medical Genetics and Genomics Board of Directors is pleased to announce the appointment of Azra Ligon, PhD, FACMG, as its new Chief Executive Officer, effective January 1, 2025. Read more on her background here: bit.ly/4goBqDV
Spatial and functional visualization of tau from the Hyman lab! In situ seeding assay: A novel technique for direct tissue localization of bioactive tau academic.oup.com/jnen/article-a…
Team Pathology is walking Now in the @TheJimmyFund Walk!! Donate now to help fund cancer research!



PCV benefit vs TMZ in #oligodendroglioma from POLA Network and @MTouatMD lab on Survival Outcomes Associated With First-Line Procarbazine, CCNU, and Vincristine or Temozolomide in Combination With Radiotherapy in IDH-Mutant 1p/19q-Codeleted Grade 3 Oligodendroglioma | Journal of…
Impressive work in @NatureMedicine using functional precision medicine to find new therapy approaches in #gbm patients. Congrats to friends in Weller and Snijder labs! #fpm rdcu.be/dU95p