Janira Navarro

Histology of Breast at Various Ages Dr. Hoda. Histology Bootcamp-Breast #USCAP25 #PathX #pathology

Breast-Histology Bootcamp Radiation changes: Does not affect all the cells uniformily Post-chemo atrophy: Breasts of young women can resemble those of 80-year-olds Dr. Hoda #USCAP25 #PathX #pathology

Breast- Benign multinucleated stromal giant cells can be seen in: -In unremarkable breast tissue or fibroepithelial lesions -Cytokeratin negative -Low proliferation rate -Uncertain etiology and significance Dr. Hoda, Breast Histology Bootcamp #USCAP25 #PathX #pathology

Choroid Plexus Tumors -Papilloma, Ki67 <5% -Atypical papilloma, Ki67~10% -Carcinoma, Ki67~20% Dr. Ballester #USCAP25 #PathX #pathology

CAR-T associated GI injury -Reduced plasma cells in lamina propria -Architectural distortion -Intraepithelial lymphocytosis -Mucin-depleted regenerative glands -Apoptotic debris -Severity of epithelial injury is disproportionate to the amount of lamina propria inflammation…

Metastasis to the thyroid Most often renal, breast and lung For secondary squamous cell carcinoma involving thyroid most often from direct extension from larynx and esophagus Dr. Viswanathan #USCAP25 #PathX #pathology

Differential diagnosis of carcinoma with squamous differentiation in the Thyroid Gland -Not every squamous cell carcinoma in the thyroid is anaplastic carcinoma Dr. Wiswanathan #USCAP25 #PathX #pathology

Adrenocortical carcinomas-Scoring system No single system has been shown to be completely sensitive or specific in all settings. The Reticulin Algorithm has a more simplified approach (see pic 2) Dr. Mete #USCAP25 #PathX #pathology

Reconsider a classic pure Mucinous Carcinoma diagnosis if you see red flag/atypical features (pic 1) -It should not be High grade -It should be pure (classified on excision specimen) -It should be HER2 negative and ER positive Breast Evening Specialty Conference-Dr. Allison…

Not all mucin-producing lesions in the breast are Mucinous Carcinoma Dr. Allison #USCAP25 #pathology #PathX

I hope to see you at the Fall Residents Forum Meeting on Saturday, September 13th at #CAP25 in Orlando, FL! @Pathologists Register and learn more here: events.cap.org/event/cap25/ho…

Daily approach to Prostate Cancer-Dr. Hirsch Use IHC when clinically relevant Low grade carcinoma -First time diagnosis, do not settle on ASAP ➡️stain High grade carcinoma -Invasive vs intraductal carcinoma: only stain if changes grade -Do not stain with keratin to determine…

beautifully juxtaposed ductal pattern prostatic adenocarcinoma (left) + acinar pattern prostatic adenocarcinoma (right) #GUpath radical prostatectomy

Prostate-Active Surveillance-Pathology Criteria - Gleason score 6/Grade group 1 - 4 or fewer (1/3) cores involved by carcinoma - <50% volumen of carcinoma in any given core Practical approach to signing out GU pathology cases-Dr.Hirsch #USCAP25 #PathX #pathology

Practical approach to signing out GU pathology cases-Dr.Hirsch Low grade, low volume carcinoma: Active surveillance Intermediate grade, increased volume: Radical prostatectomy (RP), radiation + androgen deprivation therapy (ADT) High grade, variable volume: RP, Radiation +ADT,…

A Day in the Sign Out- GU Path Gleason pattern 3: Doughnut-like structures Gleason pattern 4: Cinnamon roll like structures and poorly formed glands. Lot of subjetivity in this pattern, there is more than one correct answer most of the time Gleason pattern 5: Doughnut holes…

Prostate cancer diagnosis Lack of basal cells (most sensitive); they have a triangular shape (Hershey kiss) Practical approach to signing out GU pathology cases-Dr. Hirsch #USCAP25 #PathX #pathology

Biliary tract biopsy-10 tips to recognize cancer when conventional criteria fail you 1. Dysplasia does not produce a stricture, this finding almost always represent carcinoma 2. Most adenocarcinomas do not elicit desmoplasia when invading the mucosa 3. Abrupt transitions between…