Jurgen Claassen
@J_C_MD_PhD
Geriatrician, scientist, Radboudumc, Alzheimer,Hypertension-Brainbloodflow, Donders Institute. Author ‘Wat kun je doen aan dementie?’
Congrats for your paper and thanks for choosing @_JCBFM! #StrokeResearch #Neuroscience #Ischemia #Neuroprotection #DrugDiscovery #TranslationalMedicine #serRS #ScienceCollaboration
🚨 We identified serRS as a novel drug target with potent anti-ischemic effects, both in vitro and in vivo. This highlights the feasibility of developing serRS inhibitors as prospective #stroke #therapeutics. Check it out @_JCBFM 👉 journals.sagepub.com/share/5GWQIIZD… #DrugDiscovery
Useful diagnostic imaging tips for acute onset neurological symptoms suggestive of autoimmune encephalitis:T1-Weighted Spin Echo Sequence and Encephalitis jamanetwork.com/journals/jaman…
ScienceGuardians - defending your right for fraudulent science. All this woke stuff where you get harassed if you publish creatively made-up data. What’s the world coming to.
📢🚨 IMPORTANT ANNOUNCEMENT Retraction Watch is an institutional‑level predatory arm of the PubPeer Network Mob, designed to smear targeted researchers’ reputations. They recycle compromised journalists to advance their agenda. ⚠️⚠️ We, at ScienceGuardians™, strongly advise…
Interested in discovering the must-read 2025 articles from Journal of Cerebral Blood Flow & Metabolism? Check out the editor’s choice collection now: ow.ly/yu7G50Wq9M0 #NeurovascularResearch @_JCBFM
In a new #ScienceReview, researchers provide a critical evaluation of research linking glymphatic dysfunction with Alzheimer’s disease. scim.ag/44Hh18I
🚨 Curious how ketone bodies shield the brain from metabolic stress? 🛡️ This new #HotTopic shows β-hydroxybutyrate (BHB) reduces stroke infarct size in vivo. 🔗 Uncover the neuroprotective power of BHB: journals.sagepub.com/doi/full/10.11… #JCBFMhome #ISCBFM #NeuroTwitter #Stroke
From political unrest to toxic air and social stress, the world around us can accelerate the aging process. Out today in @NatureMedicine: our work on how the environment seeps into health and makes us older 1/6🧵 doi.org/10.1038/s41591… @EricTopol @jayvanbavel @GBHI_Fellows…
A new study from the lab @NatureMedicine Over 6,000 proteins, more than 10,500 individuals. #Alzheimers, #Parkinsons, and #FTD. @Ali_bioinformtx maps the shared and disease-specific plasma proteomic landscape of neurodegeneration @WashUNeurology nature.com/articles/s4159…
Researchers have been sneaking secret messages into their papers in an effort to trick AI tools into giving them a positive peer-review report Read the full story: go.nature.com/4eVTIwC
100 procent vegan: 'Van plant naar mens is veel logischer dan via koe'. oost.nl/nieuws/3541745…
On the potential risk of gabapentin (Neurontin) for mild cognitive impairment and dementia rapm.bmj.com/content/early/…
Researchers have been sneaking secret messages into their papers in an effort to trick AI tools into giving them a positive peer-review report go.nature.com/3TCHqPM
“My sister was killed by my ‘nurse’ mum’s twisted conspiracy theories: nobody else should go through this” cosmopolitan.com/uk/reports/a65…
📌I saw a Japanese commentator this morning—a learned scholar specializing in American government and politics—who noted that the level of writing in the letters, along with the fact that they were almost all carbon copies sent to various nations without..
This. Blood-based biomarkers for Alzheimer's disease should only be used in the context of a specialist dementia diagnosis assessment. Their use in primary care can only cause problems.
The Limited Role of Alzheimer Disease Blood-Based Biomarkers in Primary Care jamanetwork.com/journals/jamai… via @EWidera & @geri_doc @ProfRobHoward @dr_shibley @lucypgeridoc @ajlees
Great show by @Finkmusic yesterday night in #Nijmegen #doornroosje at Goffertpark.
Interesting study; I’m mostly intrigued by the 10% of centenarians who have no AD pathology, and by the 5 centenarians with high amyloid load yet normal cognition.
Amyloid-beta accumulation in centenarians is associated with reduced cognitive performance and is not a benign aspect of aging. ja.ma/4lskuhU
‘As I get older I want to be seen in terms of doors that might still open for me, not ones that have already closed.’ This is something I hope I’m doing in my outpatient clinic. For example in patients with dementia: ‘focus on what you can stil do well’. bmj.com/content/389/bm…
Don’t miss the new @_JCBFM editor’s choice collection! Browse articles on blood transit time, cerebral perfusion, and hemiplegic migraines now: ow.ly/kp1050W7RvF #CerebralBloodFlow #EditorsChoice
Here is the latest work from @LawrenceLabrecq (PhD paper #4) related to cerebral pressure-flow relationship directional sensitivity ! Ahead of print in @ExpPhysiol (open access) @jonathan_smirl @MarcAntoineRoy_ @mahmoudrezatagh @Shahrza22488635 physoc.onlinelibrary.wiley.com/doi/10.1113/EP…